| GPCR-G protein-β-arrestin super-complex mediates sustained G protein signaling ARB Thomsen, B Plouffe, TJ Cahill, AK Shukla, JT Tarrasch, AM Dosey, ... Cell 166 (4), 907-919, 2016 | 475 | 2016 |
| Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region AJ Venkatakrishnan, X Deupi, G Lebon, FM Heydenreich, T Flock, ... Nature 536 (7617), 484-487, 2016 | 295 | 2016 |
| Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor S Isogai, X Deupi, C Opitz, FM Heydenreich, CJ Tsai, F Brueckner, ... Nature 530 (7589), 237-241, 2016 | 190 | 2016 |
| A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling A Beautrait, JS Paradis, B Zimmerman, J Giubilaro, L Nikolajev, ... Nature communications 8 (1), 15054, 2017 | 123 | 2017 |
| Stabilization of G protein-coupled receptors by point mutations FM Heydenreich, Z Vuckovic, M Matkovic, DB Veprintsev Frontiers in pharmacology 6, 82, 2015 | 89 | 2015 |
| How GPCR phosphorylation patterns orchestrate arrestin-mediated signaling NR Latorraca, M Masureel, SA Hollingsworth, FM Heydenreich, ... Cell 183 (7), 1813-1825. e18, 2020 | 78 | 2020 |
| Nitrogen and Carbon Status Are Integrated at the Transcriptional Level by the Nitrogen Regulator NtrC In Vivo J Schumacher, V Behrends, Z Pan, DR Brown, F Heydenreich, MR Lewis, ... MBio 4 (6), e00881-13, 2013 | 61 | 2013 |
| GPCR activation mechanisms across classes and macro/microscales AS Hauser, AJ Kooistra, C Munk, FM Heydenreich, DB Veprintsev, ... Nature structural & molecular biology 28 (11), 879-888, 2021 | 55 | 2021 |
| Activity of the mycobacterial proteasomal ATPase Mpa is reversibly regulated by pupylation CL Delley, F Striebel, FM Heydenreich, D Özcelik, E Weber-Ban Journal of Biological Chemistry 287 (11), 7907-7914, 2012 | 44 | 2012 |
| AAscan, PCRdesign and MutantChecker: a suite of programs for primer design and sequence analysis for high-throughput scanning mutagenesis D Sun, MK Ostermaier, FM Heydenreich, D Mayer, R Jaussi, J Standfuss, ... PLoS One 8 (10), e78878, 2013 | 41 | 2013 |
| High-throughput mutagenesis using a two-fragment PCR approach FM Heydenreich, T Miljuš, R Jaussi, R Benoit, D Milić, DB Veprintsev Scientific reports 7 (1), 1-11, 2017 | 40 | 2017 |
| GlnK facilitates the dynamic regulation of bacterial nitrogen assimilation A Gosztolai, J Schumacher, V Behrends, JG Bundy, F Heydenreich, ... Biophysical journal 112 (10), 2219-2230, 2017 | 21 | 2017 |
| The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites JB Hedderich, M Persechino, K Becker, FM Heydenreich, T Gutermuth, ... Nature Communications 13 (1), 2567, 2022 | 17 | 2022 |
| Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics J Janetzko, R Kise, B Barsi-Rhyne, DH Siepe, FM Heydenreich, ... Cell 185 (24), 4560-4573. e19, 2022 | 10 | 2022 |
| Functional solubilisation of the β2-adrenoceptor (β2AR) using Diisobutylene maleic acid (DIBMA) CR Harwood, DA Sykes, B Hoare, FM Heydenreich, R Uddin, DR Poyner, ... bioRxiv, 2020.06. 29.171512, 2020 | 10* | 2020 |
| Membrane phosphoinositides stabilize GPCR-arrestin complexes and offer temporal control of complex assembly and dynamics J Janetzko, R Kise, B Barsi-Ryne, DH Siepe, FM Heydenreich, ... Biorxiv, 2021.10. 09.463790, 2021 | 7 | 2021 |
| Medical relevance of common protein-altering variants in GPCR genes across 337,205 individuals in the UK Biobank study C DeBoever, AJ Venkatakrishnan, JM Paggi, FM Heydenreich, SA Laurin, ... bioRxiv, 2019.12. 13.876250, 2019 | 3 | 2019 |
| Computationally designed GPCR quaternary structures bias signaling pathway activation JS Paradis, X Feng, B Murat, RE Jefferson, B Sokrat, M Szpakowska, ... Nature Communications 13 (1), 6826, 2022 | 2 | 2022 |
| Dissecting the allosteric networks governing agonist efficacy and potency in G protein-coupled receptors FM Heydenreich, M Marti-Solano, M Sandhu, BK Kobilka, M Bouvier, ... bioRxiv, 2021.09. 14.460253, 2021 | 2 | 2021 |
| Vasopressin V2 is a promiscuous G protein-coupled receptor that is biased by its peptide ligands FM Heydenreich, B Plouffe, A Rizk, D Milić, J Zhou, B Breton, C Le Gouill, ... bioRxiv, 2021.01. 28.427950, 2021 | 2 | 2021 |
Michel BouvierProfessor of Biochem. and Mol. Med., IRIC, Univ. de MontréalVerified email at umontreal.ca
