| Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors GM Alexander, SC Rogan, AI Abbas, BN Armbruster, Y Pei, JA Allen, ... Neuron 63 (1), 27-39, 2009 | 1018 | 2009 |
| Lipid raft microdomains and neurotransmitter signalling JA Allen, RA Halverson-Tamboli, MM Rasenick Nature Reviews Neuroscience 8 (2), 128-140, 2007 | 1015 | 2007 |
| Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons HS Huang, JA Allen, AM Mabb, IF King, J Miriyala, B Taylor-Blake, ... Nature, 2011 | 388 | 2011 |
| Reactive oxygen disrupts mitochondria in MA-10 tumor Leydig cells and inhibits steroidogenic acute regulatory (StAR) protein and steroidogenesis T Diemer, JA Allen, KH Hales, DB Hales Endocrinology 144 (7), 2882-2891, 2003 | 383 | 2003 |
| Discovery of β-arrestin–biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy JA Allen, JM Yost, V Setola, X Chen, MF Sassano, M Chen, S Peterson, ... Proceedings of the National Academy of Sciences 108 (45), 18488-18493, 2011 | 378 | 2011 |
| Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings GS Dichter, CA Damiano, JA Allen Journal of neurodevelopmental disorders 4 (1), 1-43, 2012 | 366 | 2012 |
| Strategies to discover unexpected targets for drugs active at G protein-coupled receptors JA Allen, BL Roth Annual review of pharmacology and toxicology 51, 117-144, 2011 | 240 | 2011 |
| Rapid modulation of spine morphology by the 5-HT2A serotonin receptor through kalirin-7 signaling KA Jones, DP Srivastava, JA Allen, RT Strachan, BL Roth, P Penzes Proceedings of the National Academy of Sciences 106 (46), 19575-19580, 2009 | 225 | 2009 |
| Mitochondrial function in Leydig cell steroidogenesis DB HALES, JA ALLEN, T SHANKARA, P JANUS, S BUCK, T DIEMER, ... Annals of the New York Academy of Sciences 1061 (1), 120-134, 2005 | 176 | 2005 |
| Energized, polarized, and actively respiring mitochondria are required for acute Leydig cell steroidogenesis JA Allen, T Shankara, P Janus, S Buck, T Diemer, K Held Hales, DB Hales Endocrinology 147 (8), 3924-3935, 2006 | 163 | 2006 |
| Bacterial endotoxin lipopolysaccharide and reactive oxygen species inhibit Leydig cell steroidogenesis via perturbation of mitochondria JA Allen, T Diemer, P Janus, KH Hales, DB Hales Endocrine 25 (3), 265-275, 2004 | 155 | 2004 |
| Parallel functional activity profiling reveals valvulopathogens are potent 5-hydroxytryptamine2B receptor agonists: implications for drug safety assessment XP Huang, V Setola, PN Yadav, JA Allen, SC Rogan, BJ Hanson, ... Molecular pharmacology 76 (4), 710-722, 2009 | 136 | 2009 |
| β-Adrenergic receptor stimulation promotes Gαs internalization through lipid rafts: a study in living cells JA Allen, ZY Jiang, RJ Donati, MM Rasenick Molecular pharmacology 67 (5), 1493-1504, 2005 | 136 | 2005 |
| Caveolin-1 and lipid microdomains regulate Gs trafficking and attenuate Gs/adenylyl cyclase signaling JA Allen, ZY Jiang, RH Dave, A Bhatnagar, BL Roth, MM Rasenick Molecular pharmacology 76 (5), 1082-1093, 2009 | 102 | 2009 |
| Impaired β-arrestin recruitment and reduced desensitization by non-catechol agonists of the D1 dopamine receptor DL Gray, JA Allen, S Mente, RE O’Connor, GJ DeMarco, I Efremov, ... Nature communications 9 (1), 674, 2018 | 85 | 2018 |
| Structure-based design, synthesis, and biochemical and pharmacological characterization of novel salvinorin A analogues as active state probes of the κ-opioid receptor F Yan, RV Bikbulatov, V Mocanu, N Dicheva, CE Parker, WC Wetsel, ... Biochemistry 48 (29), 6898-6908, 2009 | 79 | 2009 |
| A chemical-genetic approach for precise spatio-temporal control of cellular signaling S Dong, JA Allen, M Farrell, BL Roth Mol. BioSyst. 6 (8), 1376-1380, 2010 | 72 | 2010 |
| Insights into the regulation of 5-HT2A serotonin receptors by scaffolding proteins and kinases JA Allen, PN Yadav, BL Roth Neuropharmacology 55 (6), 961-968, 2008 | 62 | 2008 |
| Cytosolic Gαs acts as an intracellular messenger to increase microtubule dynamics and promote neurite outgrowth JZ Yu, RH Dave, JA Allen, T Sarma, MM Rasenick Journal of Biological Chemistry 284 (16), 10462-10472, 2009 | 61 | 2009 |
| Schizophrenia risk gene CAV1 is both pro-psychotic and required for atypical antipsychotic drug actions in vivo JA Allen, PN Yadav, V Setola, M Farrell, BL Roth Translational Psychiatry 1 (8), e33, 2011 | 37 | 2011 |
BL RothDepartment of Pharmacology, University of North Carolina Medical SchoolVerified email at med.unc.edu
