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Christina I Schroeder
Christina I Schroeder
Peptide Therapeutics, Genentech, South San Francisco, CA
Verified email at gene.com
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Cited by
Year
AChBP‐targeted α‐conotoxin correlates distinct binding orientations with nAChR subtype selectivity
S Dutertre, C Ulens, R Büttner, A Fish, R van Elk, Y Kendel, G Hopping, ...
The EMBO journal 26 (16), 3858-3867, 2007
1982007
Rational design and synthesis of an orally bioavailable peptide guided by NMR amide temperature coefficients
CK Wang, SE Northfield, B Colless, S Chaousis, I Hamernig, RJ Lohman, ...
Proceedings of the National Academy of Sciences 111 (49), 17504-17509, 2014
1552014
Disulfide-rich macrocyclic peptides as templates in drug design
SE Northfield, CK Wang, CI Schroeder, T Durek, MW Kan, JE Swedberg, ...
European Journal of Medicinal Chemistry 77, 248-257, 2014
1402014
ω-Conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals
DJ Adams, AB Smith, CI Schroeder, T Yasuda, RJ Lewis
Journal of biological chemistry 278 (6), 4057-4062, 2003
1322003
Structure–activity relationships of ω‐conotoxins at N‐type voltage‐sensitive calcium channels
KJ Nielsen, T Schroeder, R Lewis
Journal of Molecular Recognition 13 (2), 55-70, 2000
1322000
Fmoc-based synthesis of disulfide-rich cyclic peptides
O Cheneval, CI Schroeder, T Durek, P Walsh, YH Huang, S Liras, ...
The Journal of organic chemistry 79 (12), 5538-5544, 2014
1282014
Semienzymatic cyclization of disulfide-rich peptides using Sortase A
X Jia, S Kwon, CIA Wang, YH Huang, LY Chan, CC Tan, KJ Rosengren, ...
Journal of biological chemistry 289 (10), 6627-6638, 2014
992014
The α2δ auxiliary subunit reduces affinity of ω-conotoxins for recombinant N-type (Cav2. 2) calcium channels
J Mould, T Yasuda, CI Schroeder, AM Beedle, CJ Doering, GW Zamponi, ...
Journal of Biological Chemistry 279 (33), 34705-34714, 2004
992004
χ-Conopeptide pharmacophore development: Toward a novel class of norepinephrine transporter inhibitor (Xen2174) for pain
A Brust, E Palant, DE Croker, B Colless, R Drinkwater, B Patterson, ...
Journal of medicinal chemistry 52 (22), 6991-7002, 2009
952009
Identification of a novel class of nicotinic receptor antagonists: dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum
M Loughnan, A Nicke, A Jones, CI Schroeder, ST Nevin, DJ Adams, ...
Journal of biological chemistry 281 (34), 24745-24755, 2006
872006
Inhibition of the norepinephrine transporter by the venom peptide χ-MrIA: Site of action, Na+ dependence, and structure-activity relationship
IA Sharpe, E Palant, CI Schroeder, DM Kaye, DJ Adams, PF Alewood, ...
Journal of Biological Chemistry 278 (41), 40317-40323, 2003
832003
Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro
CI Schroeder, JE Swedberg, JM Withka, KJ Rosengren, M Akcan, ...
Chemistry & biology 21 (2), 284-294, 2014
802014
Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin‐2
CI Schroeder, LD Rash, X Vila‐Farrés, KJ Rosengren, M Mobli, GF King, ...
Angewandte Chemie International Edition 53 (4), 1017-1020, 2014
792014
Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1. 7
ST Henriques, E Deplazes, N Lawrence, O Cheneval, S Chaousis, ...
Journal of Biological Chemistry 291 (33), 17049-17065, 2016
782016
Isolation and structure-activity of μ-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels
RJ Lewis, CI Schroeder, J Ekberg, KJ Nielsen, M Loughnan, L Thomas, ...
Molecular pharmacology 71 (3), 676-685, 2007
762007
Synthesis and biological evaluation of nonpeptide mimetics of ω-conotoxin GVIA
JB Baell, PJ Duggan, SA Forsyth, RJ Lewis, YP Lok, CI Schroeder
Bioorganic & medicinal chemistry 12 (15), 4025-4037, 2004
762004
N-type calcium channel blockers: novel therapeutics for the treatment of pain
CI Schroeder, CJ Doering, GW Zamponi, RJ Lewis
Medicinal Chemistry 2 (5), 535-543, 2006
752006
A novel α4/7-conotoxin LvIA from Conus lividus that selectively blocks α3β2 vs. α6/α3β2β3 nicotinic acetylcholine receptors
S Luo, D Zhangsun, CI Schroeder, X Zhu, Y Hu, Y Wu, MM Weltzin, ...
The FASEB Journal 28 (4), 1842, 2014
73*2014
Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed
TA Hill, RJ Lohman, HN Hoang, DS Nielsen, CCG Scully, WM Kok, L Liu, ...
ACS medicinal chemistry letters 5 (10), 1148-1151, 2014
652014
Approaches to the stabilization of bioactive epitopes by grafting and peptide cyclization
AC Conibear, S Chaousis, T Durek, K Johan Rosengren, DJ Craik, ...
Peptide Science 106 (1), 89-100, 2016
622016
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