| A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade DS Thommen, VH Koelzer, P Herzig, A Roller, M Trefny, S Dimeloe, ... Nature medicine 24 (7), 994-1004, 2018 | 876 | 2018 |
| Successful anti-PD-1 cancer immunotherapy requires T cell-dendritic cell crosstalk involving the cytokines IFN-γ and IL-12 CS Garris, SP Arlauckas, RH Kohler, MP Trefny, S Garren, C Piot, ... Immunity 49 (6), 1148-1161. e7, 2018 | 762 | 2018 |
| CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors H Wang, F Franco, YC Tsui, X Xie, MP Trefny, R Zappasodi, SR Mohmood, ... Nature immunology 21 (3), 298-308, 2020 | 388 | 2020 |
| Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells MA Stanczak, SS Siddiqui, MP Trefny, DS Thommen, KF Boligan, ... The Journal of clinical investigation 128 (11), 4912-4923, 2018 | 229 | 2018 |
| Hepatic stellate cells suppress NK cell-sustained breast cancer dormancy AL Correia, JC Guimaraes, P Auf der Maur, D De Silva, MP Trefny, ... Nature 594 (7864), 566-571, 2021 | 171 | 2021 |
| Magnesium sensing via LFA-1 regulates CD8+ T cell effector function J Lötscher, AAM i Líndez, N Kirchhammer, E Cribioli, G Giordano, ... Cell, 2022 | 94 | 2022 |
| PD-1+ natural killer cells in human non-small cell lung cancer can be activated by PD-1/PD-L1 blockade MP Trefny, M Kaiser, MA Stanczak, P Herzig, S Savic, M Wiese, ... Cancer Immunology, Immunotherapy 69 (8), 1505-1517, 2020 | 69 | 2020 |
| Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade MA Stanczak, NR Mantuano, N Kirchhammer, DE Sanin, J Wang, ... BioRxiv, 2021 | 64 | 2021 |
| GEF-H1 Signaling upon Microtubule Destabilization Is Required for Dendritic Cell Activation and Specific Anti-tumor Responses AS Kashyap, L Fernandez-Rodriguez, Y Zhao, G Monaco, MP Trefny, ... Cell reports 28 (13), 3367-3380. e8, 2019 | 44 | 2019 |
| A variant of a killer cell immunoglobulin-like receptor is associated with resistance to PD-1 blockade in lung cancer MP Trefny, SI Rothschild, F Uhlenbrock, D Rieder, B Kasenda, ... Clinical Cancer Research 25 (10), 3026-3034, 2019 | 35 | 2019 |
| NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunity N Kirchhammer, MP Trefny, M Natoli, D Brücher, SN Smith, F Werner, ... Science Translational Medicine 14 (653), eabm9043, 2022 | 34 | 2022 |
| Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy MP Trefny, N Kirchhammer, P Auf der Maur, M Natoli, D Schmid, ... Nature Communications 14 (1), 86, 2023 | 20 | 2023 |
| Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential H Liu, Z He, SL April, MP Trefny, JS Rougier, S Salemi, R Olariu, ... Cell Death & Differentiation 26 (6), 1048-1061, 2019 | 11 | 2019 |
| N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer PA der Maur, MP Trefny, Z Baumann, M Vulin, AL Correia, M Diepenbruck, ... Cell Reports Medicine, 2023 | 4 | 2023 |
| Successful IL-12 cancer immunotherapy requires NK cell-derived CCL5 for anti-tumor DC-T cell crosstalk N Kirchhammer, MP Trefny, M Natoli, D Brücher, SN Smith, F Werner, ... bioRxiv, 2021 | 2 | 2021 |
| Dual TLR9 and PD-L1 targeting unleashes dendritic cells to induce durable antitumor immunity L Fernandez-Rodriguez, C Cianciaruso, R Bill, MP Trefny, R Klar, ... Journal for Immunotherapy of Cancer 11 (5), 2023 | 1 | 2023 |
| Unraveling T-cell Exhaustion: Genetic Screening Meets In Vitro Modeling D Schmid, P Auf der Maur, MP Trefny, A Zippelius Cancer Research 83 (23), 3830-3832, 2023 | | 2023 |
| Multimodal single-cell profiling of T cell specificity and reactivity in lung cancer F Bieberich, R Vazquez-Lombardi, H Jin, KL Hong, P Herzig, M Trefny, ... bioRxiv, 2023.10. 04.560863, 2023 | | 2023 |
Alfred ZippeliusProfessor of Translational Oncology, Co-Head Medical OncologyBestätigte E-Mail-Adresse bei usb.ch
