gian gaetano tartaglia
gian gaetano tartaglia
IIT (Sapienza / ICREA / CRG / University of Cambridge / University of Zurich)
Verified email at - Homepage
Cited by
Cited by
ALS/FTD mutation-induced phase transition of FUS liquid droplets and reversible hydrogels into irreversible hydrogels impairs RNP granule function
T Murakami, S Qamar, JQ Lin, GSK Schierle, E Rees, A Miyashita, ...
Neuron 88 (4), 678-690, 2015
Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions
H Olzscha, SM Schermann, AC Woerner, S Pinkert, MH Hecht, ...
Cell 144 (1), 67-78, 2011
FUS phase separation is modulated by a molecular chaperone and methylation of arginine cation-π interactions
S Qamar, GZ Wang, SJ Randle, FS Ruggeri, JA Varela, JQ Lin, ...
Cell 173 (3), 720-734. e15, 2018
Prediction of aggregation-prone regions in structured proteins
GG Tartaglia, AP Pawar, S Campioni, CM Dobson, F Chiti, M Vendruscolo
Journal of molecular biology 380 (2), 425-436, 2008
Metastability of native proteins and the phenomenon of amyloid formation
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, ...
Journal of the American Chemical Society 133 (36), 14160-14163, 2011
DnaK functions as a central hub in the E. coli chaperone network
G Calloni, T Chen, SM Schermann, H Chang, P Genevaux, F Agostini, ...
Cell reports 1 (3), 251-264, 2012
Predicting protein associations with long noncoding RNAs
M Bellucci, F Agostini, M Masin, GG Tartaglia
Nature methods 8 (6), 444-445, 2011
The Zyggregator method for predicting protein aggregation propensities
GG Tartaglia, M Vendruscolo
Chemical Society Reviews 37 (7), 1395-1401, 2008
Life on the edge: a link between gene expression levels and aggregation rates of human proteins
GG Tartaglia, S Pechmann, CM Dobson, M Vendruscolo
Trends in biochemical sciences 32 (5), 204-206, 2007
Mendelian randomization
E Birney
Cold Spring Harbor perspectives in medicine, a041302, 2021
Widespread aggregation and neurodegenerative diseases are associated with supersaturated proteins
P Ciryam, GG Tartaglia, RI Morimoto, CM Dobson, M Vendruscolo
Cell reports 5 (3), 781-790, 2013
catRAPID omics: a web server for large-scale prediction of protein–RNA interactions
F Agostini, A Zanzoni, P Klus, D Marchese, D Cirillo, GG Tartaglia
Bioinformatics 29 (22), 2928-2930, 2013
A concentration-dependent liquid phase separation can cause toxicity upon increased protein expression
B Bolognesi, NL Gotor, R Dhar, D Cirillo, M Baldrighi, GG Tartaglia, ...
Cell reports 16 (1), 222-231, 2016
Prediction of aggregation rate and aggregation‐prone segments in polypeptide sequences
GG Tartaglia, A Cavalli, R Pellarin, A Caflisch
Protein science 14 (10), 2723-2734, 2005
Systematic in vivo analysis of the intrinsic determinants of amyloid β pathogenicity
LM Luheshi, GG Tartaglia, AC Brorsson, AP Pawar, IE Watson, F Chiti, ...
PLoS biology 5 (11), e290, 2007
The role of aromaticity, exposed surface, and dipole moment in determining protein aggregation rates
GG Tartaglia, A Cavalli, R Pellarin, A Caflisch
Protein Science 13 (7), 1939-1941, 2004
Physicochemical principles that regulate the competition between functional and dysfunctional association of proteins
S Pechmann, ED Levy, GG Tartaglia, M Vendruscolo
Proceedings of the National Academy of Sciences 106 (25), 10159-10164, 2009
Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19
L Gaziano, C Giambartolomei, AC Pereira, A Gaulton, DC Posner, ...
Nature medicine 27 (4), 668-676, 2021
RNA structure drives interaction with proteins
N Sanchez de Groot, A Armaos, R Graña-Montes, M Alriquet, G Calloni, ...
Nature communications 10 (1), 3246, 2019
Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate
K Yanamandra, O Alexeyev, V Zamotin, V Srivastava, A Shchukarev, ...
PloS one 4 (5), e5562, 2009
The system can't perform the operation now. Try again later.
Articles 1–20