Andrew N. Blackford
Andrew N. Blackford
Principal Investigator, University of Oxford
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ATM, ATR, and DNA-PK: the trinity at the heart of the DNA damage response
AN Blackford, SP Jackson
Molecular cell 66 (6), 801-817, 2017
PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair
T Ochi, AN Blackford, J Coates, S Jhujh, S Mehmood, N Tamura, ...
Science 347 (6218), 185-188, 2015
ATR activation and replication fork restart are defective in FANCM‐deficient cells
RA Schwab, AN Blackford, W Niedzwiedz
The EMBO journal 29 (4), 806-818, 2010
Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair
SE Polo, AN Blackford, JR Chapman, L Baskcomb, S Gravel, A Rusch, ...
Molecular cell 45 (4), 505-516, 2012
Adenovirus E1B 55-kilodalton protein: multiple roles in viral infection and cell transformation
AN Blackford, RJA Grand
Journal of virology 83 (9), 4000-4012, 2009
BOD1L is required to suppress deleterious resection of stressed replication forks
MR Higgs, JJ Reynolds, A Winczura, AN Blackford, V Borel, ES Miller, ...
Molecular cell 59 (3), 462-477, 2015
Adenovirus 12 E4orf6 inhibits ATR activation by promoting TOPBP1 degradation
AN Blackford, RN Patel, NA Forrester, K Theil, P Groitl, GS Stewart, ...
Proceedings of the National Academy of Sciences 107 (27), 12251-12256, 2010
Serotype-specific inactivation of the cellular DNA damage response during adenovirus infection
NA Forrester, GG Sedgwick, A Thomas, AN Blackford, T Speiseder, ...
Journal of virology 85 (5), 2201-2211, 2011
The DNA translocase activity of FANCM protects stalled replication forks
AN Blackford, RA Schwab, J Nieminuszczy, AJ Deans, SC West, ...
Human molecular genetics 21 (9), 2005-2016, 2012
A role for E1B-AP5 in ATR signaling pathways during adenovirus infection
AN Blackford, RK Bruton, O Dirlik, GS Stewart, AMR Taylor, T Dobner, ...
Journal of virology 82 (15), 7640-7652, 2008
TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism
ME Harley, O Murina, A Leitch, MR Higgs, LS Bicknell, G Yigit, ...
Nature genetics 48 (1), 36-43, 2016
TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution
R Broderick, J Nieminuszczy, AN Blackford, A Winczura, W Niedzwiedz
Nature communications 6 (1), 1-12, 2015
Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression
K Townsend, H Mason, AN Blackford, ES Miller, JR Chapman, ...
Journal of Biological Chemistry 284 (49), 33939-33948, 2009
Synthetic lethality between PAXX and XLF in mammalian development
G Balmus, AC Barros, PWG Wijnhoven, C Lescale, HL Hasse, K Boroviak, ...
Genes & development 30 (19), 2152-2157, 2016
Specific roles of XRCC4 paralogs PAXX and XLF during V (D) J recombination
C Lescale, HL Hasse, AN Blackford, G Balmus, JJ Bianchi, W Yu, ...
Cell reports 16 (11), 2967-2979, 2016
USP4 auto-deubiquitylation promotes homologous recombination
P Wijnhoven, R Konietzny, AN Blackford, J Travers, BM Kessler, R Nishi, ...
Molecular cell 60 (3), 362-373, 2015
TopBP1 interacts with BLM to maintain genome stability but is dispensable for preventing BLM degradation
AN Blackford, J Nieminuszczy, RA Schwab, Y Galanty, SP Jackson, ...
Molecular cell 57 (6), 1133-1141, 2015
PGBD5 promotes site-specific oncogenic mutations in human tumors
AG Henssen, R Koche, J Zhuang, E Jiang, C Reed, A Eisenberg, E Still, ...
Nature genetics 49 (7), 1005, 2017
The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity
JR Becker, R Cuella-Martin, M Barazas, R Liu, C Oliveira, AW Oliver, ...
Nature communications 9 (1), 1-12, 2018
MDC1 interacts with TOPBP1 to maintain chromosomal stability during mitosis
PA Leimbacher, SE Jones, AMK Shorrocks, M de Marco Zompit, M Day, ...
Molecular cell 74 (3), 571-583. e8, 2019
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