A therapeutically targetable mechanism of BCR-ABL–independent imatinib resistance in chronic myeloid leukemia L Ma, Y Shan, R Bai, L Xue, CA Eide, J Ou, LJ Zhu, L Hutchinson, J Cerny, ... Science translational medicine 6 (252), 252ra121-252ra121, 2014 | 138 | 2014 |
A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice A Illendula, JA Pulikkan, H Zong, J Grembecka, L Xue, S Sen, Y Zhou, ... Science 347 (6223), 779-784, 2015 | 122 | 2015 |
Thrombopoietin/MPL participates in initiating and maintaining RUNX1-ETO acute myeloid leukemia via PI3K/AKT signaling JA Pulikkan, D Madera, L Xue, P Bradley, SF Landrette, YH Kuo, S Abbas, ... Blood, The Journal of the American Society of Hematology 120 (4), 868-879, 2012 | 57 | 2012 |
Map4k4 negatively regulates peroxisome proliferator-activated receptor (PPAR) γ protein translation by suppressing the mammalian target of rapamycin (mTOR) signaling pathway in … KVP Guntur, A Guilherme, L Xue, A Chawla, MP Czech Journal of Biological Chemistry 285 (9), 6595-6603, 2010 | 45 | 2010 |
NrasG12D oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis L Xue, JA Pulikkan, PJM Valk, LH Castilla Blood, The Journal of the American Society of Hematology 124 (3), 426-436, 2014 | 28 | 2014 |
Selective inhibition of the leukemia fusion protein CBFβ-SMMHC by small molecule AI-10-49 in the treatment of Inv (16) AML JA Pulikkan, A Illendula, J Grembecka, L Xue, R Rajewski, ML Guzman, ... Blood 124 (21), 390, 2014 | 3 | 2014 |
PKC pathways mediate BCR-ABL-independent imatinib resistance in chronic myeloid leukemia L Ma, Y Shan, R Bai, L Xue, CA Eide, J Ou, LJ Zhu, L Hutchinson, J Cerny, ... Blood 124 (21), 1790, 2014 | 2 | 2014 |
A Small Molecule Inhibitor of the CBFβ-SMMHC/RUNX Interaction Attenuates Inv (16) Leukemia in Vivo JH Bushweller, A Illendula, JA Pulikkan, J Grembecka, P Bradley, Y Zhou, ... Blood 120 (21), 286, 2012 | 1 | 2012 |
Oncogene Function in Pre-Leukemia Stage of INV (16) Acute Myeloid Leukemia: A Dissertation L Xue | | 2014 |
NrasG12D oncogenic protein inhibits apoptotic Bim factor in preleukemic progenitors and synergizes with CBFβ-SMMHC in acute myeloid leukemia L Xue, LH Castilla | | 2012 |
Map4k4 egatively Regulates PPARr Protein Translation by Suppressing the mTOR Signaling Pathway in Cultured Adipocytes KVP Guntur, A Guilherme, L Xue, A Chawla, MP Czech | | 2009 |