Interactions between gut microbiota, host genetics and diet modulate the predisposition to obesity and metabolic syndrome S Ussar, NW Griffin, O Bezy, S Fujisaka, S Vienberg, S Softic, L Deng, ... Cell metabolism 22 (3), 516-530, 2015 | 570 | 2015 |
Hepatic insulin resistance directly promotes formation of cholesterol gallstones SB Biddinger, JT Haas, BB Yu, O Bezy, E Jing, W Zhang, TG Unterman, ... Nature medicine 14 (7), 778-782, 2008 | 389 | 2008 |
Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance C Vernochet, A Mourier, O Bezy, Y Macotela, J Boucher, MJ Rardin, D An, ... Cell metabolism 16 (6), 765-776, 2012 | 255 | 2012 |
Characterization of the long pentraxin PTX3 as a TNFα-induced secreted protein of adipose cells A Abderrahim-Ferkoune, O Bezy, C Chiellini, M Maffei, P Grimaldi, ... Journal of lipid research 44 (5), 994-1000, 2003 | 179 | 2003 |
PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans O Bezy, TT Tran, J Pihlajamäki, R Suzuki, B Emanuelli, J Winnay, MA Mori, ... The Journal of clinical investigation 121 (6), 2504-2517, 2011 | 171 | 2011 |
Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications C Vernochet, F Damilano, A Mourier, O Bezy, MA Mori, G Smyth, ... The FASEB Journal 28 (10), 4408, 2014 | 163 | 2014 |
TRB3 blocks adipocyte differentiation through the inhibition of C/EBPβ transcriptional activity O Bezy, C Vernochet, S Gesta, SR Farmer, CR Kahn Molecular and cellular biology 27 (19), 6818-6831, 2007 | 115 | 2007 |
Glypican-4 enhances insulin signaling via interaction with the insulin receptor and serves as a novel adipokine S Ussar, O Bezy, M Blüher, CR Kahn Diabetes 61 (9), 2289-2298, 2012 | 108 | 2012 |
A kinase-independent role for unoccupied insulin and IGF-1 receptors in the control of apoptosis J Boucher, Y Macotela, O Bezy, MA Mori, K Kriauciunas, CR Kahn Science signaling 3 (151), ra87-ra87, 2010 | 93 | 2010 |
Mesodermal developmental gene Tbx15 impairs adipocyte differentiation and mitochondrial respiration S Gesta, O Bezy, MA Mori, Y Macotela, KY Lee, CR Kahn Proceedings of the National Academy of Sciences 108 (7), 2771-2776, 2011 | 90 | 2011 |
Transdifferentiation of preadipose cells into smooth muscle-like cells: role of aortic carboxypeptidase-like protein A Abderrahim-Ferkoune, O Bezy, S Astri-Roques, C Elabd, G Ailhaud, ... Experimental cell research 293 (2), 219-228, 2004 | 87 | 2004 |
A systems biology approach identifies inflammatory abnormalities between mouse strains prior to development of metabolic disease MA Mori, M Liu, O Bezy, K Almind, H Shapiro, S Kasif, CR Kahn Diabetes 59 (11), 2960-2971, 2010 | 76 | 2010 |
Metabolic syndrome: is Nlrp3 inflammasome a trigger or a target of insulin resistance? MA Mori, O Bezy, CR Kahn Circulation research 108 (10), 1160-1162, 2011 | 51 | 2011 |
Delta-interacting protein A, a new inhibitory partner of CCAAT/enhancer-binding protein β, implicated in adipocyte differentiation O Bezy, C Elabd, O Cochet, RK Petersen, K Kristiansen, C Dani, ... Journal of Biological Chemistry 280 (12), 11432-11438, 2005 | 43 | 2005 |
Role of PKCδ in insulin sensitivity and skeletal muscle metabolism M Li, SG Vienberg, O Bezy, BT O’Neill, CR Kahn Diabetes 64 (12), 4023-4032, 2015 | 42 | 2015 |
Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation E Fung, L Kang, D Sapashnik, S Benard, A Sievers, Y Liu, G Yan, J Zhou, ... Scientific reports 11 (1), 8921, 2021 | 14 | 2021 |
Growth differentiation factor 15 neutralization does not impact anorexia or survival in lipopolysaccharide-induced inflammation DM Breen, S Jagarlapudi, A Patel, C Zou, S Joaquim, X Li, L Kang, ... Iscience 24 (6), 2021 | 10 | 2021 |
LPS induces rapid increase in GDF15 levels in mice, rats, and humans but is not required for anorexia in mice AR Patel, H Frikke-Schmidt, O Bezy, PV Sabatini, N Rittig, N Jessen, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 322 (2 …, 2022 | 8 | 2022 |
Use of protein kinase c delta (pkcd) inhibitors to treat diabetes, obesity, and hepatic steatosis CR Kahn, O Bezy US Patent App. 13/497,172, 2012 | 7 | 2012 |
Attenuation of PKC δ enhances metabolic activity and promotes expansion of blood progenitors TN Rao, MK Gupta, S Softic, LD Wang, YC Jang, T Thomou, O Bezy, ... The EMBO Journal 37 (24), e100409, 2018 | 4 | 2018 |