Modulating oxytocin activity and plasma stability by disulfide bond engineering M Muttenthaler, A Andersson, AD de Araujo, Z Dekan, RJ Lewis, ... Journal of medicinal chemistry 53 (24), 8585-8596, 2010 | 131 | 2010 |
Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptides S Dutertre, D Croker, NL Daly, A Andersson, M Muttenthaler, ... Journal of Biological Chemistry 283 (11), 7100-7108, 2008 | 97 | 2008 |
Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species M Muttenthaler, Å Andersson, I Vetter, R Menon, M Busnelli, ... Science signaling 10 (508), eaan3398, 2017 | 40 | 2017 |
Conopeptide-derived κ-opioid agonists (Conorphins): potent, selective, and metabolic stable dynorphin A mimetics with antinociceptive properties A Brust, DE Croker, B Colless, L Ragnarsson, Å Andersson, K Jain, ... Journal of medicinal chemistry 59 (6), 2381-2395, 2016 | 33 | 2016 |
Conopeptide ρ-TIA Defines a New Allosteric Site on the Extracellular Surface of the α1B-Adrenoceptor*♦ L Ragnarsson, CIA Wang, Å Andersson, D Fajarningsih, T Monks, A Brust, ... Journal of biological chemistry 288 (3), 1814-1827, 2013 | 32 | 2013 |
Mutations in the NPxxY motif stabilize pharmacologically distinct conformational states of the α1B- and β2-adrenoceptors L Ragnarsson, Å Andersson, WG Thomas, RJ Lewis Science signaling 12 (572), eaas9485, 2019 | 29 | 2019 |
ω-Conotoxin GVIA mimetics based on an anthranilamide core: Effect of variation in ammonium side chain lengths and incorporation of fluorine A Andersson, JB Baell, PJ Duggan, JE Graham, RJ Lewis, NG Lumsden, ... Bioorganic & medicinal chemistry 17 (18), 6659-6670, 2009 | 20 | 2009 |
Improving the gastrointestinal stability of linaclotide N Braga Emidio, HNT Tran, A Andersson, PE Dawson, F Albericio, I Vetter, ... Journal of Medicinal Chemistry 64 (12), 8384-8390, 2021 | 18 | 2021 |
Extracellular surface residues of the α1B-adrenoceptor critical for G protein–coupled receptor function L Ragnarsson, Å Andersson, WG Thomas, RJ Lewis Molecular pharmacology 87 (1), 121-129, 2015 | 10 | 2015 |
In vitro profiling of opioid ligands using the cAMP formation inhibition assay and the β-arrestin2 recruitment assay: No two ligands have the same profile A Kuo, J Magiera, N Rethwan, Å Andersson, AL Lam, B Wyse, ... European Journal of Pharmacology 872, 172947, 2020 | 9 | 2020 |
Synthesis of multivalent [Lys8]-oxytocin dendrimers that inhibit visceral nociceptive responses J Wan, M Mobli, A Brust, M Muttenthaler, Å Andersson, L Ragnarsson, ... Australian Journal of Chemistry 70 (2), 162-171, 2016 | 9 | 2016 |
Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function S Jami, JR Deuis, T Klasfauseweh, X Cheng, S Kurdyukov, F Chung, ... Nature Communications 14 (1), 2442, 2023 | 6 | 2023 |
The α1-adrenoceptor inhibitor ρ-TIA facilitates net hunting in piscivorous Conus tulipa M Dutt, J Giacomotto, L Ragnarsson, Å Andersson, A Brust, Z Dekan, ... Scientific Reports 9 (1), 17841, 2019 | 6 | 2019 |
A Chemoenzymatic Approach To Produce a Cyclic Analogue of the Analgesic Drug MVIIA (Ziconotide) Y Zhou, PJ Harvey, J Koehbach, LY Chan, A Jones, Å Andersson, I Vetter, ... Angewandte Chemie 135 (29), e202302812, 2023 | 3 | 2023 |
The structural conformation of the tachykinin domain drives the anti‐tumoural activity of an octopus peptide in melanoma BRAFV600E J Moral‐Sanz, MA Fernandez‐Rojo, G Colmenarejo, S Kurdyukov, ... British Journal of Pharmacology 179 (20), 4878-4896, 2022 | 2 | 2022 |
GRIN1 variants associated with neurodevelopmental disorders reveal channel gating pathomechanisms L Ragnarsson, Z Zhang, SS Das, P Tran, Å Andersson, V Des Portes, ... Epilepsia 64 (12), 3377-3388, 2023 | 1 | 2023 |
Self-assembly of alkylated lysine-dendron oxytocin amphiphiles for enhanced stability and sustained pharmacological activity F Xie, Y Lin, Å Andersson, I Vetter, L Zhao, JJ Wan Chemical Communications 59 (93), 13855-13858, 2023 | 1 | 2023 |
The Allosteric Binding Site for rho-TIA on the Extracellular Surface of the alpha 1B-Adrenoceptor L Ragnarsson, CIA Wang, Å Andersson, D Fajarningsih, T Monks, A Brust, ... Toxicon 60 (2), 164-164, 2012 | 1 | 2012 |
How to differentiate induced pluripotent stem cells into sensory neurons for disease modelling: a functional assessment AK Kalia, C Rösseler, R Granja-Vazquez, A Ahmad, JJ Pancrazio, ... Stem Cell Research & Therapy 15 (1), 99, 2024 | | 2024 |
Anti-seizure mechanisms of midazolam and valproate at the?(L51M) variant of the GABA (A) receptor br A Kuanyshbek, M Wang, A Andersson, M Tuifua, EE Palmer, RK Sachdev, ... NEUROPHARMACOLOGY 221, 2022 | | 2022 |