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Sophie Dutheil
Sophie Dutheil
Senior Scientist at Intra-Cellular Therapies, Inc.
Verified email at itci-inc.com
Title
Cited by
Cited by
Year
Psychological stress activates the inflammasome via release of adenosine triphosphate and stimulation of the purinergic type 2X7 receptor
M Iwata, KT Ota, XY Li, F Sakaue, N Li, S Dutheil, M Banasr, V Duric, ...
Biological psychiatry 80 (1), 12-22, 2016
3732016
High-fat diet induced anxiety and anhedonia: impact on brain homeostasis and inflammation
S Dutheil, KT Ota, ES Wohleb, K Rasmussen, RS Duman
Neuropsychopharmacology 41 (7), 1874-1887, 2016
3512016
REDD1 is essential for stress-induced synaptic loss and depressive behavior
KT Ota, RJ Liu, B Voleti, JG Maldonado-Aviles, V Duric, M Iwata, S Dutheil, ...
Nature medicine 20 (5), 531-535, 2014
2722014
Rapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptors
A Navarria, ES Wohleb, B Voleti, KT Ota, S Dutheil, AE Lepack, JM Dwyer, ...
Neurobiology of disease 82, 254-261, 2015
1122015
Role of neuronal VEGF signaling in the prefrontal cortex in the rapid antidepressant effects of ketamine
S Deyama, E Bang, ES Wohleb, XY Li, T Kato, DM Gerhard, S Dutheil, ...
American Journal of Psychiatry 176 (5), 388-400, 2019
962019
Neurogenesis and astrogenesis contribution to recovery of vestibular functions in the adult cat following unilateral vestibular neurectomy: cellular and behavioral evidence
S Dutheil, JM Brezun, J Leonard, M Lacour, B Tighilet
Neuroscience 164 (4), 1444-1456, 2009
902009
Tell me your vestibular deficit, and I’ll tell you how you’ll compensate
M Lacour, S Dutheil, B Tighilet, C Lopez, L Borel
Annals of the New York Academy of Sciences 1164 (1), 268-278, 2009
872009
Ketamine strengthens CRF-activated amygdala inputs to basal dendrites in mPFC layer V pyramidal cells in the prelimbic but not infralimbic subregion, a key suppressor of stress …
RJ Liu, KT Ota, S Dutheil, RS Duman, GK Aghajanian
Neuropsychopharmacology 40 (9), 2066-2075, 2015
642015
Neurogenic potential of the vestibular nuclei and behavioural recovery time course in the adult cat are governed by the nature of the vestibular damage
S Dutheil, M Lacour, B Tighilet
PLoS One 6 (8), e22262, 2011
492011
GABAA Receptor agonist and antagonist alter vestibular compensation and different steps of reactive neurogenesis in deafferented vestibular nuclei of adult cats
S Dutheil, G Escoffier, A Gharbi, I Watabe, B Tighilet
Journal of Neuroscience 33 (39), 15555-15566, 2013
442013
BDNF signaling promotes vestibular compensation by increasing neurogenesis and remodeling the expression of potassium-chloride cotransporter KCC2 and GABAA receptor in the …
S Dutheil, I Watabe, K Sadlaoud, A Tonetto, B Tighilet
Journal of Neuroscience 36 (23), 6199-6212, 2016
422016
Reactive Neurogenesis and Down-Regulation of the Potassium-Chloride Cotransporter KCC2 in the Cochlear Nuclei after Cochlear Deafferentation.
NAJ Tighilet B, Dutheil S, Siponen MI
Front Pharmacol 7 (281), 2016
232016
Lumateperone-mediated effects on prefrontal glutamatergic receptor-mediated neurotransmission: A dopamine D1 receptor dependent mechanism
J Titulaer, O Radhe, K Danielsson, S Dutheil, MM Marcus, K Jardemark, ...
European Neuropsychopharmacology 62, 22-35, 2022
192022
Vascular ageing features caused by selective DNA damage in smooth muscle cell
EA Ataabadi, K Golshiri, J van der Linden, M de Boer, DJ Duncker, ...
Oxidative Medicine and Cellular Longevity 2021, 2021
172021
Lumateperone normalizes pathological levels of acute inflammation through important pathways known to be involved in mood regulation
S Dutheil, LS Watson, RE Davis, GL Snyder
Journal of Neuroscience 43 (5), 863-877, 2023
112023
Selective phosphodiesterase 1 inhibition ameliorates vascular function, reduces inflammatory response, and lowers blood pressure in aging animals
K Golshiri, EA Ataabadi, E Rubio-Beltran, S Dutheil, W Yao, GL Snyder, ...
Journal of Pharmacology and Experimental Therapeutics 378 (2), 173-183, 2021
102021
Discovering a new functional neurogenic zone: the vestibular nuclei of the brainstem
S Dutheil, M Lacour, B Tighilet
Medecine Sciences: M/S 27 (6-7), 605-613, 2011
92011
Lumateperone uniquely enhances glutamatergic neurotransmission through activation of both NMDA and AMPA channels via a dopamine D1 receptor-dependent mechanism: implications …
T Svensson, S Dutheil, J Hendrick, L Zhang, L Wennogle, C O'Gorman, ...
Neuropsychopharmacology 43, S160-S161, 2017
42017
P. 0764 Lumateperone increases glutamate release in the rat medial prefrontal cortex
J Titulaer, MM Marcus, R Davis, S Dutheil, G Snyder, A Fienberg, ...
European Neuropsychopharmacology 53, S556-S557, 2021
22021
SUPPRESSION OF CNS INFLAMMATION BY PHOSPHODIESTERASE-1 (PDE1) INHIBITORS: TOWARD NEW TREATMENTS FOR NEURODEGENERATIVE DISEASES
GL Snyder, S Dutheil, JL O'Brien, S Cruz, Y Tian, JP Hendrick, ...
Alzheimer's & Dementia 13 (7), P1579, 2017
22017
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