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Tom van Wezel
Tom van Wezel
Associate professor, Department of Pathology, Leiden University Medical Center, Netherlands
Verified email at lumc.nl - Homepage
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Cited by
Year
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23. 3
IPM Tomlinson, E Webb, L Carvajal-Carmona, P Broderick, K Howarth, ...
Nature genetics 40 (5), 623-630, 2008
6362008
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome
TC Pansuriya, R Van Eijk, P d'Adamo, MAJH Van Ruler, ML Kuijjer, ...
Nature genetics 43 (12), 1256-1261, 2011
5102011
E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines
M Lombaerts, T Van Wezel, K Philippo, JWF Dierssen, RME Zimmerman, ...
British journal of cancer 94 (5), 661-671, 2006
4242006
Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer
J Drost, R Van Boxtel, F Blokzijl, T Mizutani, N Sasaki, V Sasselli, J de Ligt, ...
Science 358 (6360), 234-238, 2017
3292017
Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers
CAL Ruivenkamp, T van Wezel, C Zanon, APM Stassen, C Vlcek, ...
Nature genetics 31 (3), 295-300, 2002
2952002
Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study
E Domingo, L Freeman-Mills, E Rayner, M Glaire, S Briggs, L Vermeulen, ...
The lancet Gastroenterology & hepatology 1 (3), 207-216, 2016
2202016
A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16. 1 (REL), 8q24. 21 and 10p14 (GATA3)
V Enciso-Mora, P Broderick, Y Ma, RF Jarrett, H Hjalgrim, K Hemminki, ...
Nature genetics 42 (12), 1126-1130, 2010
2192010
Rapid KRAS, EGFR, BRAF and PIK3CA Mutation Analysis of Fine Needle Aspirates from Non-Small-Cell Lung Cancer Using Allele-Specific qPCR
R van Eijk, J Licht, M Schrumpf, M Talebian Yazdi, D Ruano, GI Forte, ...
PloS one 6 (3), e17791, 2011
2092011
Practical guidance for mismatch repair-deficiency testing in endometrial cancer
E Stelloo, AML Jansen, EM Osse, RA Nout, CL Creutzberg, D Ruano, ...
Annals of Oncology 28 (1), 96-102, 2017
1842017
Gene interaction and single gene effects in colon tumour susceptibility in mice
T Wezel, APM Stassen, CJA Moen, AAM Hart, MA van der Valk, P Demant
Nature genetics 14 (4), 468-470, 1996
1651996
Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK
PW Voorneveld, LL Kodach, RJ Jacobs, N Liv, AC Zonnevylle, ...
Gastroenterology 147 (1), 196-208. e13, 2014
1552014
Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell ‘stemness’ via the bone morphogenetic …
LL Kodach, RJ Jacobs, PW Voorneveld, ME Wildenberg, HW Verspaget, ...
Gut 60 (11), 1544-1553, 2011
1482011
Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex genetic alterations in cervical cancer
JN Kloth, J Oosting, T van Wezel, K Szuhai, J Knijnenburg, A Gorter, ...
BMC genomics 8 (1), 53, 2007
1322007
Kinome profiling of chondrosarcoma reveals SRC-pathway activity and dasatinib as option for treatment
YM Schrage, IH Briaire-de Bruijn, NFCC de Miranda, J van Oosterwijk, ...
Cancer Research 69 (15), 6216-6222, 2009
1222009
Expression of HLA class I antigen, aspirin use, and survival after a diagnosis of colon cancer
MS Reimers, E Bastiaannet, RE Langley, R van Eijk, RLP van Vlierberghe, ...
JAMA internal medicine 174 (5), 732-739, 2014
1192014
Mutational signature analysis reveals NTHL1 deficiency to cause a multi-tumor phenotype
JE Grolleman, RM De Voer, FA Elsayed, M Nielsen, RDA Weren, C Palles, ...
Cancer cell 35 (2), 256-266. e5, 2019
1142019
Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer
FA Elsayed, CM Kets, D Ruano, B Van Den Akker, AR Mensenkamp, ...
European Journal of Human Genetics 23 (8), 1080-1084, 2015
1122015
The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression
AM Pittman, S Naranjo, E Webb, P Broderick, EH Lips, T Van Wezel, ...
Genome research 19 (6), 987-993, 2009
1122009
HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression
JWF Dierssen, NFCC de Miranda, S Ferrone, M van Puijenbroek, ...
BMC cancer 7 (1), 1-11, 2007
1102007
Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers
AML Jansen, T Van Wezel, BE Van Den Akker, M Ventayol Garcia, ...
European Journal of Human Genetics 24 (7), 1089-1092, 2016
1092016
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