Chia-Huey Ooi
Chia-Huey Ooi
Bioinformatics Scientist, Roche Pharma Research and Early Development (pRED)
Verified email at
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Genetic algorithms applied to multi-class prediction for the analysis of gene expression data
CH Ooi, P Tan
Bioinformatics 19 (1), 37-44, 2003
Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy
IB Tan, T Ivanova, KH Lim, CW Ong, N Deng, J Lee, SH Tan, J Wu, ...
Gastroenterology 141 (2), 476-485. e11, 2011
Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil
Z Lei, IB Tan, K Das, N Deng, H Zouridis, S Pattison, C Chua, Z Feng, ...
Gastroenterology 145 (3), 554-565, 2013
Oncogenic pathway combinations predict clinical prognosis in gastric cancer
CH Ooi, T Ivanova, J Wu, M Lee, IB Tan, J Tao, L Ward, JH Koo, ...
PLoS Genet 5 (10), e1000676, 2009
STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation
H Tye, CL Kennedy, M Najdovska, L McLeod, W McCormack, N Hughes, ...
Cancer cell 22 (4), 466-478, 2012
Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade
M Schmittnaegel, N Rigamonti, E Kadioglu, A Cassará, CW Rmili, ...
Science translational medicine 9 (385), 2017
Genomic loss of miR-486 regulates tumor progression and the OLFM4 antiapoptotic factor in gastric cancer
HK Oh, ALK Tan, K Das, CH Ooi, NT Deng, IBH Tan, E Beillard, J Lee, ...
Clinical cancer research 17 (9), 2657-2667, 2011
Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity
C Baer, ML Squadrito, D Laoui, D Thompson, SK Hansen, A Kiialainen, ...
Nature cell biology 18 (7), 790-802, 2016
Comprehensive genomic meta-analysis identifies intra-tumoural stroma as a predictor of survival in patients with gastric cancer
Y Wu, H Grabsch, T Ivanova, IB Tan, J Murray, CH Ooi, AI Wright, NP West, ...
Gut 62 (8), 1100-1111, 2013
Integrated epigenomics identifies BMP4 as a modulator of cisplatin sensitivity in gastric cancer
T Ivanova, H Zouridis, Y Wu, LL Cheng, IB Tan, V Gopalakrishnan, ...
Gut 62 (1), 22-33, 2013
Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity
S Hoves, CH Ooi, C Wolter, H Sade, S Bissinger, M Schmittnaegel, O Ast, ...
Journal of Experimental Medicine 215 (3), 859-876, 2018
Patterns of large-scale genomic variation in virulent and avirulent Burkholderia species
C Ong, CH Ooi, D Wang, H Chong, KC Ng, F Rodrigues, MA Lee, P Tan
Genome research 14 (11), 2295-2307, 2004
CD44-SLC1A2 gene fusions in gastric cancer
J Tao, NT Deng, K Ramnarayanan, B Huang, HK Oh, SH Leong, SS Lim, ...
Science translational medicine 3 (77), 77ra30-77ra30, 2011
Integrative genomic, transcriptional, and proteomic diversity in natural isolates of the human pathogen Burkholderia pseudomallei
K Ou, C Ong, SY Koh, F Rodrigues, SH Sim, D Wong, CH Ooi, KC Ng, ...
Journal of bacteriology 187 (12), 4276-4285, 2005
Differential prioritization between relevance and redundancy in correlation-based feature selection techniques for multiclass gene expression data
CH Ooi, M Chetty, SW Teng
BMC bioinformatics 7 (1), 320, 2006
Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response
C Salvagno, M Ciampricotti, S Tuit, CS Hau, A van Weverwijk, SB Coffelt, ...
Nature cell biology 21 (4), 511-521, 2019
The molecular pathogenesis of STAT3‐driven gastric tumourigenesis in mice is independent of IL‐17
CL Kennedy, M Najdovska, GW Jones, L McLeod, NR Hughes, C Allison, ...
The Journal of pathology 225 (2), 255-264, 2011
Macrophage susceptibility to emactuzumab (RG7155) treatment
LP Pradel, CH Ooi, S Romagnoli, MA Cannarile, H Sade, D Rüttinger, ...
Molecular cancer therapeutics 15 (12), 3077-3086, 2016
A densely interconnected genome-wide network of microRNAs and oncogenic pathways revealed using gene expression signatures
CH Ooi, HK Oh, HZA Wang, ALK Tan, J Wu, M Lee, SY Rha, HC Chung, ...
PLoS Genet 7 (12), e1002415, 2011
Differential prioritization in feature selection and classifier aggregation for multiclass microarray datasets
CH Ooi, M Chetty, SW Teng
Data Mining and Knowledge Discovery 14 (3), 329-366, 2007
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