Cancer as a metabolic disease TN Seyfried, LM Shelton Nutrition & metabolism 7, 1-22, 2010 | 918 | 2010 |
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance D Kim, BP Fiske, K Birsoy, E Freinkman, K Kami, RL Possemato, ... Nature 520 (7547), 363-367, 2015 | 375 | 2015 |
Differential glutamate metabolism in proliferating and quiescent mammary epithelial cells JL Coloff, JP Murphy, CR Braun, IS Harris, LM Shelton, K Kami, SP Gygi, ... Cell metabolism 23 (5), 867-880, 2016 | 280 | 2016 |
RETRACTED: PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis D Samanta, Y Park, SA Andrabi, LM Shelton, DM Gilkes, GL Semenza Cancer research 76 (15), 4430-4442, 2016 | 245 | 2016 |
Metabolic management of brain cancer TN Seyfried, MA Kiebish, J Marsh, LM Shelton, LC Huysentruyt, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1807 (6), 577-594, 2011 | 192 | 2011 |
Arginine deprivation inhibits the Warburg effect and upregulates glutamine anaplerosis and serine biosynthesis in ASS1-deficient cancers JC Kremer, BC Prudner, SES Lange, GR Bean, MB Schultze, ... Cell reports 18 (4), 991-1004, 2017 | 139 | 2017 |
Glutamine targeting inhibits systemic metastasis in the VM‐M3 murine tumor model LM Shelton, LC Huysentruyt, TN Seyfried International journal of cancer 127 (10), 2478-2485, 2010 | 128 | 2010 |
Metastatic cancer cells with macrophage properties: evidence from a new murine tumor model LC Huysentruyt, P Mukherjee, D Banerjee, LM Shelton, TN Seyfried International journal of cancer 123 (1), 73-84, 2008 | 98 | 2008 |
Is the restricted ketogenic diet a viable alternative to the standard of care for managing malignant brain cancer? TN Seyfried, J Marsh, LM Shelton, LC Huysentruyt, P Mukherjee Epilepsy research 100 (3), 310-326, 2012 | 97 | 2012 |
Calorie restriction as an anti-invasive therapy for malignant brain cancer in the VM mouse LM Shelton, LC Huysentruyt, P Mukherjee, TN Seyfried ASN neuro 2 (3), AN20100002, 2010 | 80 | 2010 |
A novel pre-clinical in vivo mouse model for malignant brain tumor growth and invasion LM Shelton, P Mukherjee, LC Huysentruyt, I Urits, JA Rosenberg, ... Journal of neuro-oncology 99, 165-176, 2010 | 72 | 2010 |
Does the existing standard of care increase glioblastoma energy metabolism? TN Seyfried, LM Shelton, P Mukherjee The lancet oncology 11 (9), 811-813, 2010 | 65 | 2010 |
Thematic review series: sphingolipids. Ganglioside GM3 suppresses the proangiogenic effects of vascular endothelial growth factor and ganglioside GD1a P Mukherjee, AC Faber, LM Shelton, RC Baek, TC Chiles, TN Seyfried Journal of lipid research 49 (5), 929-938, 2008 | 64 | 2008 |
MUC1* ligand, NM23-H1, is a novel growth factor that maintains human stem cells in a more naive state BJ Smagghe, AK Stewart, MG Carter, LM Shelton, KJ Bernier, EJ Hartman, ... PloS one 8 (3), e58601, 2013 | 50 | 2013 |
Provocative question: should ketogenic metabolic therapy become the standard of care for glioblastoma? TN Seyfried, L Shelton, G Arismendi-Morillo, M Kalamian, A Elsakka, ... Neurochemical research 44, 2392-2404, 2019 | 48 | 2019 |
Influence of methotrexate and cisplatin on tumor progression and survival in the VM mouse model of systemic metastatic cancer LC Huysentruyt, LM Shelton, TN Seyfried International journal of cancer 126 (1), 65-72, 2010 | 37 | 2010 |
Ganglioside GM3 suppresses the pro-angiogenic effects of vascular endothelial growth factor and ganglioside GD1A P Mukherjee, AC Faber, LM Shelton, RC Baek, TC Chiles, TN Seyfried J Lipid Res 49 (5), 929-938, 2008 | 24 | 2008 |
Quantification of folate metabolism using transient metabolic flux analysis PM Tedeschi, N Johnson-Farley, H Lin, LM Shelton, T Ooga, G Mackay, ... Cancer & metabolism 3, 1-14, 2015 | 23 | 2015 |
Mycoplasma infection and hypoxia initiate succinate accumulation and release in the VM-M3 cancer cells RE Flores, AK Brown, L Taus, J Khoury, F Glover, K Kami, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1859 (9), 975-983, 2018 | 22 | 2018 |
Targeting pheochromocytoma/paraganglioma with polyamine inhibitors SK Rai, F Bril, HM Hatch, Y Xu, L Shelton, S Kalavalapalli, A Click, D Lee, ... Metabolism 110, 154297, 2020 | 15 | 2020 |