|Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1|
F Urano, XZ Wang, A Bertolotti, Y Zhang, P Chung, HP Harding, D Ron
Science 287 (5453), 664-666, 2000
|IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA|
M Calfon, H Zeng, F Urano, JH Till, SR Hubbard, HP Harding, SG Clark, ...
Nature 415 (6867), 92-96, 2002
|Autophagy is activated for cell survival after endoplasmic reticulum stress|
M Ogata, S Hino, A Saito, K Morikawa, S Kondo, S Kanemoto, T Murakami, ...
Molecular and cellular biology 26 (24), 9220-9231, 2006
|Transcriptional and translational control in the Mammalian unfolded protein response|
HP Harding, M Calfon, F Urano, I Novoa, D Ron
Annual review of cell and developmental biology 18 (1), 575-599, 2002
|Measuring ER stress and the unfolded protein response using mammalian tissue culture system|
CM Oslowski, F Urano
Methods in enzymology 490, 71-92, 2011
|Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome|
CM Oslowski, T Hara, B O'Sullivan-Murphy, K Kanekura, S Lu, M Hara, ...
Cell metabolism 16 (2), 265-273, 2012
|Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1|
KL Lipson, SG Fonseca, S Ishigaki, LX Nguyen, E Foss, R Bortell, ...
Cell metabolism 4 (3), 245-254, 2006
|Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones|
T Yoneda, C Benedetti, F Urano, SG Clark, HP Harding, D Ron
Journal of cell science 117 (18), 4055-4066, 2004
|Amyloid β induces neuronal cell death through ROS-mediated ASK1 activation|
H Kadowaki, H Nishitoh, F Urano, C Sadamitsu, A Matsuzawa, K Takeda, ...
Cell Death & Differentiation 12 (1), 19, 2005
|WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic β-cells|
SG Fonseca, M Fukuma, KL Lipson, LX Nguyen, JR Allen, Y Oka, F Urano
Journal of Biological Chemistry 280 (47), 39609-39615, 2005
|Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells|
SG Fonseca, S Ishigaki, CM Oslowski, S Lu, KL Lipson, R Ghosh, ...
The Journal of clinical investigation 120 (3), 744-755, 2010
|Endoplasmic reticulum stress and pancreatic β-cell death|
SG Fonseca, J Gromada, F Urano
Trends in Endocrinology & Metabolism 22 (7), 266-274, 2011
|IRE1 and efferent signaling from the endoplasmic reticulum|
F Urano, A Bertolotti, D Ron
Journal of cell science 113 (21), 3697-3702, 2000
|Male sterility and enhanced radiation sensitivity in TLS−/− mice|
M Kuroda, J Sok, L Webb, H Baechtold, F Urano, Y Yin, P Chung, ...
The EMBO journal 19 (3), 453-462, 2000
|A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response|
F Urano, M Calfon, T Yoneda, C Yun, M Kiraly, SG Clark, D Ron
The Journal of cell biology 158 (4), 639-646, 2002
|Transcriptional regulation of VEGF-A by the unfolded protein response pathway|
R Ghosh, KL Lipson, KE Sargent, AM Mercurio, JS Hunt, D Ron, F Urano
PloS one 5 (3), 2010
|The role of IRE1α in the degradation of insulin mRNA in pancreatic β-cells|
KL Lipson, R Ghosh, F Urano
PloS one 3 (2), 2008
|Fluoride induces endoplasmic reticulum stress in ameloblasts responsible for dental enamel formation|
K Kubota, DH Lee, M Tsuchiya, CS Young, ET Everett, EA Martinez-Mier, ...
Journal of Biological Chemistry 280 (24), 23194-23202, 2005
|A novel chimera gene between EWS and E1A-F, encoding the adenovirus E1A enhancer-binding protein, in extraosseous Ewing's sarcoma|
F Urano, A Umezawa, W Hong, H Kikuchi, J Hata
Biochemical and biophysical research communications 219 (2), 608-612, 1996
|Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions|
S Ishigaki, A Masuda, Y Fujioka, Y Iguchi, M Katsuno, A Shibata, F Urano, ...
Scientific reports 2, 529, 2012