Suivre
Wenxiang Hu
Wenxiang Hu
Guangzhou Laboratory
Adresse e-mail validée de gzlab.ac.cn
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Année
Direct conversion of normal and Alzheimer’s disease human fibroblasts into neuronal cells by small molecules
W Hu, B Qiu, W Guan, Q Wang, M Wang, W Li, L Gao, L Shen, Y Huang, ...
Cell stem cell 17 (2), 204-212, 2015
4962015
Generation of neural progenitor cells by chemical cocktails and hypoxia
L Cheng, W Hu, B Qiu, J Zhao, Y Yu, W Guan, M Wang, W Yang, G Pei
Cell research 24 (6), 665-679, 2014
2632014
Diet-induced circadian enhancer remodeling synchronizes opposing hepatic lipid metabolic processes
D Guan, Y Xiong, PC Borck, C Jang, PT Doulias, R Papazyan, B Fang, ...
Cell 174 (4), 831-842. e12, 2018
1572018
The hepatocyte clock and feeding control chronophysiology of multiple liver cell types
D Guan, Y Xiong, TM Trinh, Y Xiao, W Hu, C Jiang, P Dierickx, C Jang, ...
Science 369 (6509), 1388-1394, 2020
1082020
Direct conversion of astrocytes into neuronal cells by drug cocktail
L Cheng, L Gao, W Guan, J Mao, W Hu, B Qiu, J Zhao, Y Yu, G Pei
Cell research 25 (11), 1269-1272, 2015
942015
β-Arrestin1 regulates zebrafish hematopoiesis through binding to YY1 and relieving polycomb group repression
R Yue, J Kang, C Zhao, W Hu, Y Tang, X Liu, G Pei
Cell 139 (3), 535-546, 2009
532009
Activation of aryl hydrocarbon receptor (ahr) by tranilast, an anti-allergy drug, promotes miR-302 expression and cell reprogramming
W Hu, J Zhao, G Pei
Journal of Biological Chemistry 288 (32), 22972-22984, 2013
492013
Modelling metabolic diseases and drug response using stem cells and organoids
W Hu, MA Lazar
Nature Reviews Endocrinology 18 (12), 744-759, 2022
422022
β-Arrestin-1 protein represses diet-induced obesity
L Zhuang, W Hu, M Zhang, S Xin, W Jia, J Zhao, G Pei
Journal of Biological Chemistry 286 (32), 28396-28402, 2011
382011
Natural human genetic variation determines basal and inducible expression of PM20D1, an obesity-associated gene
KK Benson, W Hu, AH Weller, AH Bennett, ER Chen, SA Khetarpal, ...
Proceedings of the National Academy of Sciences 116 (46), 23232-23242, 2019
372019
Fear erasure facilitated by immature inhibitory neuron transplantation
WZ Yang, TT Liu, JW Cao, XF Chen, X Liu, M Wang, X Su, SQ Zhang, ...
Neuron 92 (6), 1352-1367, 2016
352016
β-arrestin-1 protein represses adipogenesis and inflammatory responses through its interaction with peroxisome proliferator-activated receptor-γ (PPARγ)
L Zhuang, W Hu, S Xin, J Zhao, G Pei
Journal of Biological Chemistry 286 (32), 28403-28413, 2011
342011
Patient adipose stem cell-derived adipocytes reveal genetic variation that predicts antidiabetic drug response
W Hu, C Jiang, D Guan, P Dierickx, R Zhang, A Moscati, GN Nadkarni, ...
Cell Stem Cell 24 (2), 299-308. e6, 2019
302019
Isoform-specific functions of PPARγ in gene regulation and metabolism
W Hu, C Jiang, M Kim, Y Xiao, HJ Richter, D Guan, K Zhu, BM Krusen, ...
Genes & Development 36 (5-6), 300-312, 2022
192022
Individual-specific functional epigenomics reveals genetic determinants of adverse metabolic effects of glucocorticoids
W Hu, C Jiang, M Kim, W Yang, K Zhu, D Guan, W Lv, Y Xiao, JR Wilson, ...
Cell metabolism 33 (8), 1592-1609. e7, 2021
182021
Hepatocytes demarcated by EphB2 contribute to the progression of nonalcoholic steatohepatitis
Y Xiao, K Batmanov, W Hu, K Zhu, AY Tom, D Guan, C Jiang, L Cheng, ...
Science translational medicine 15 (682), eadc9653, 2023
152023
An intrinsically disordered region controlling condensation of a circadian clock component and rhythmic transcription in the liver
K Zhu, IJ Celwyn, D Guan, Y Xiao, X Wang, W Hu, C Jiang, L Cheng, ...
Molecular cell 83 (19), 3457-3469. e7, 2023
72023
Hepatocyte SREBP signaling mediates clock communication within the liver
D Guan, H Bae, D Zhou, Y Chen, C Jiang, CM La, Y Xiao, K Zhu, W Hu, ...
The Journal of Clinical Investigation 133 (8), 2023
52023
Molecular and cellular regulation of thermogenic fat
C Wang, X Wang, W Hu
Frontiers in Endocrinology 14, 1215772, 2023
42023
Novel insights into the pathophysiology of diabetes-related complications: Implications for improved therapeutic strategies
J Ma, C Jiang, X Fu, J Chen, W Hu, L Yuan
Frontiers in Endocrinology 14, 1157807, 2023
12023
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