Margarita Dominguez Villar
Margarita Dominguez Villar
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Regulatory T cells in autoimmune disease
M Dominguez-Villar, DA Hafler
Nature immunology 19 (7), 665-673, 2018
Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease
M Dominguez-Villar, CM Baecher-Allan, DA Hafler
Nature medicine 17 (6), 673-675, 2011
The TIGIT/CD226 axis regulates human T cell function
E Lozano, M Dominguez-Villar, V Kuchroo, DA Hafler
The Journal of Immunology 188 (8), 3869-3875, 2012
Enhanced suppressor function of TIM‐3+FoxP3+ regulatory T cells
AS Gautron, M Dominguez‐Villar, M de Marcken, DA Hafler
European journal of immunology 44 (9), 2703-2711, 2014
The PI3K/AKT signaling pathway in regulatory T-cell development, stability, and function
SL Pompura, M Dominguez-Villar
Journal of leukocyte biology 103 (6), 1065-1076, 2018
TLR7 and TLR8 activate distinct pathways in monocytes during RNA virus infection
M de Marcken, K Dhaliwal, AC Danielsen, AS Gautron, ...
Science signaling 12 (605), eaaw1347, 2019
Modulation of regulatory T cell function and stability by co-inhibitory receptors
LE Lucca, M Dominguez-Villar
Nature Reviews Immunology 20 (11), 680-693, 2020
Droplet-based microfluidic platforms for single T cell secretion analysis of IL-10 cytokine
T Konry, M Dominguez-Villar, C Baecher-Allan, DA Hafler, ML Yarmush
Biosensors and Bioelectronics 26 (5), 2707-2710, 2011
TLR7 induces anergy in human CD4+ T cells
M Dominguez-Villar, AS Gautron, M De Marcken, MJ Keller, DA Hafler
Nature immunology 16 (1), 118-128, 2015
AKT isoforms modulate Th1‐like Treg generation and function in human autoimmune disease
A Kitz, M de Marcken, AS Gautron, M Mitrovic, DA Hafler, ...
EMBO reports 17 (8), 1169-1183, 2016
TIGIT signaling restores suppressor function of Th1 Tregs
LE Lucca, PP Axisa, ER Singer, NM Nolan, M Dominguez-Villar, ...
JCI insight 4 (3), 2019
Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity
T Sumida, MR Lincoln, CM Ukeje, DM Rodriguez, H Akazawa, T Noda, ...
Nature immunology 19 (12), 1391-1402, 2018
Regulation of NFAT by poly (ADP-ribose) polymerase activity in T cells
R Valdor, V Schreiber, L Saenz, T Martínez, A Muñoz-Suano, ...
Molecular immunology 45 (7), 1863-1871, 2008
Molecular mechanisms underlying Th1-like Treg generation and function
A Kitz, M Dominguez-Villar
Cellular and molecular life sciences 74, 4059-4075, 2017
Oleic acid restores suppressive defects in tissue-resident FOXP3 Tregs from patients with multiple sclerosis
SL Pompura, A Wagner, A Kitz, J LaPerche, N Yosef, M Dominguez-Villar, ...
The Journal of clinical investigation 131 (2), 2021
CD2 costimulation reveals defective activity by human CD4+ CD25hi regulatory cells in patients with multiple sclerosis
CM Baecher-Allan, CM Costantino, GL Cvetanovich, CW Ashley, G Beriou, ...
The Journal of Immunology 186 (6), 3317-3326, 2011
Antigen-specific regulatory T cell therapy in autoimmune diseases and transplantation
C Selck, M Dominguez-Villar
Frontiers in immunology 12, 661875, 2021
Nonapoptotic and extracellular activity of granzyme B mediates resistance to regulatory T cell (Treg) suppression by HLA-DR− CD25hiCD127lo Tregs in multiple sclerosis and in …
S Bhela, C Kempsell, M Manohar, M Dominguez-Villar, R Griffin, P Bhatt, ...
The Journal of Immunology 194 (5), 2180-2189, 2015
Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells
DM Kofler, A Marson, M Dominguez-Villar, S Xiao, VK Kuchroo, DA Hafler
The Journal of clinical investigation 124 (6), 2513-2522, 2014
Fingolimod modulates T cell phenotype and regulatory T cell plasticity in vivo
M Dominguez-Villar, K Raddassi, AC Danielsen, J Guarnaccia, DA Hafler
Journal of autoimmunity 96, 40-49, 2019
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