| Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways D Grimm, KL Streetz, CL Jopling, TA Storm, K Pandey, CR Davis, ... Nature 441 (7092), 537-541, 2006 | 2126 | 2006 |
| Novel tools for production and purification of recombinant adenoassociated virus vectors D Grimm, A Kern, K Rittner, JA Kleinschmidt Human gene therapy 9 (18), 2745-2760, 1998 | 890 | 1998 |
| In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses D Grimm, JS Lee, L Wang, T Desai, B Akache, TA Storm, MA Kay Journal of virology 82 (12), 5887-5911, 2008 | 855 | 2008 |
| The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9 B Akache, D Grimm, K Pandey, SR Yant, H Xu, MA Kay Journal of virology 80 (19), 9831-9836, 2006 | 563 | 2006 |
| Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration Y Malato, S Naqvi, N Schürmann, R Ng, B Wang, J Zape, MA Kay, ... The Journal of clinical investigation 121 (12), 4850-4860, 2011 | 519 | 2011 |
| From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy D Grimm, MA Kay Current gene therapy 3 (4), 281-304, 2003 | 459 | 2003 |
| DNA helicase‐mediated packaging of adeno‐associated virus type 2 genomes into preformed capsids JA King, R Dubielzig, D Grimm, JA Kleinschmidt The EMBO journal, 2001 | 445 | 2001 |
| Helper virus-free, optically controllable, and two-plasmid-based production of adeno-associated virus vectors of serotypes 1 to 6 D Grimm, MA Kay, JA Kleinschmidt Molecular Therapy 7 (6), 839-850, 2003 | 409 | 2003 |
| CRISPR/Cas9‐mediated genome engineering: an adeno‐associated viral (AAV) vector toolbox E Senís, C Fatouros, S Große, E Wiedtke, D Niopek, AK Mueller, K Börner, ... Biotechnology journal 9 (11), 1402-1412, 2014 | 349 | 2014 |
| Loss of epigenetic information as a cause of mammalian aging JH Yang, M Hayano, PT Griffin, JA Amorim, MS Bonkowski, ... Cell 186 (2), 305-326. e27, 2023 | 330 | 2023 |
| Subcellular compartmentalization of adeno-associated virus type 2 assembly A Wistuba, A Kern, S Weger, D Grimm, JA Kleinschmidt Journal of virology 71 (2), 1341-1352, 1997 | 306 | 1997 |
| Six RNA viruses and forty-one hosts: viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems P Parameswaran, E Sklan, C Wilkins, T Burgon, MA Samuel, R Lu, ... PLoS pathogens 6 (2), e1000764, 2010 | 305 | 2010 |
| Macrophage microRNA-155 promotes cardiac hypertrophy and failure S Heymans, MF Corsten, W Verhesen, P Carai, REW Van Leeuwen, ... Circulation 128 (13), 1420-1432, 2013 | 286 | 2013 |
| Expression of shRNA from a tissue-specific pol II promoter is an effective and safe RNAi therapeutic JC Giering, D Grimm, TA Storm, MA Kay Molecular therapy 16 (9), 1630-1636, 2008 | 275 | 2008 |
| Argonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liver D Grimm, L Wang, JS Lee, N Schürmann, S Gu, K Börner, TA Storm, ... The Journal of clinical investigation 120 (9), 3106-3119, 2010 | 264 | 2010 |
| Progress in adeno-associated virus type 2 vector production: promises and prospects for clinical use D Grimm, JA Kleinschmidt Human gene therapy 10 (15), 2445-2450, 1999 | 260 | 1999 |
| Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments S Fanucchi, ET Fok, E Dalla, Y Shibayama, K Börner, EY Chang, ... Nature genetics 51 (1), 138-150, 2019 | 259 | 2019 |
| Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy L Amoasii, C Long, H Li, AA Mireault, JM Shelton, E Sanchez-Ortiz, ... Science translational medicine 9 (418), eaan8081, 2017 | 259 | 2017 |
| Therapeutic application of RNAi: is mRNA targeting finally ready for prime time? D Grimm, MA Kay The Journal of clinical investigation 117 (12), 3633-3641, 2007 | 256 | 2007 |
| Preclinical in vivo evaluation of pseudotyped adeno-associated virus vectors for liver gene therapy D Grimm, S Zhou, H Nakai, CE Thomas, TA Storm, S Fuess, T Matsushita, ... Blood 102 (7), 2412-2419, 2003 | 255 | 2003 |
Mark A. KayStanford UniversityVerified email at stanford.edu
