Patrick Holt
Patrick Holt
Professor, Telethon Kids Institute, University of Western Australia
Verified email at
Cited by
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Development of allergen-specific T-cell memory in atopic and normal children
SL Prescott, C Macaubas, T Smallacombe, BJ Holt, PD Sly, PG Holt
The Lancet 353 (9148), 196-200, 1999
A Polymorphism* in the 5′ flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E
M Baldini, I Carla Lohman, M Halonen, RP Erickson, PG Holt, FD Martinez
American journal of respiratory cell and molecular biology 20 (5), 976-983, 1999
Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T cell responses toward the Th2 cytokine profile
SL Prescott, C Macaubas, BJ Holt, TB Smallacombe, R Loh, PD Sly, ...
The Journal of Immunology 160 (10), 4730-4737, 1998
After asthma: redefining airways diseases
ID Pavord, R Beasley, A Agusti, GP Anderson, E Bel, G Brusselle, ...
The Lancet 391 (10118), 350-400, 2018
Early-life respiratory viral infections, atopic sensitization, and risk of subsequent development of persistent asthma
MMH Kusel, NH de Klerk, T Kebadze, V Vohma, PG Holt, SL Johnston, ...
Journal of Allergy and Clinical Immunology 119 (5), 1105-1110, 2007
The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development
SM Teo, D Mok, K Pham, M Kusel, M Serralha, N Troy, BJ Holt, BJ Hales, ...
Cell host & microbe 17 (5), 704-715, 2015
Association between breast feeding and asthma in 6 year old children: findings of a prospective birth cohort study
WH Oddy, PG Holt, PD Sly, AW Read, LI Landau, FJ Stanley, GE Kendall, ...
Bmj 319 (7213), 815-819, 1999
The role of allergy in the development of asthma
PG Holt, C Macaubas, PA Stumbles, PD Sly
Nature 402 (Suppl 6760), 12-17, 1999
Downregulation of the antigen presenting cell function (s) of pulmonary dendritic cells in vivo by resident alveolar macrophages.
PG Holt, J Oliver, N Bilyk, C McMenamin, PG McMenamin, G Kraal, ...
The Journal of experimental medicine 177 (2), 397-407, 1993
Fish oil supplementation in pregnancy modifies neonatal allergen-specific immune responses and clinical outcomes in infants at high risk of atopy: a randomized, controlled trial
JA Dunstan, TA Mori, A Barden, LJ Beilin, AL Taylor, PG Holt, SL Prescott
Journal of Allergy and Clinical Immunology 112 (6), 1178-1184, 2003
A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells
JD Sedgwick, PG Holt
Journal of immunological methods 57 (1-3), 301-309, 1983
Regulation of immunological homeostasis in the respiratory tract
PG Holt, DH Strickland, ME Wikström, FL Jahnsen
Nature Reviews Immunology 8 (2), 142-152, 2008
Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/STAT5 signaling pathway
RM Bingisser, PA Tilbrook, PG Holt, UR Kees
The Journal of Immunology 160 (12), 5729-5734, 1998
The development of the immune system during pregnancy and early life
PG Holt, CA Jones
Allergy 55 (8), 688-697, 2000
Role of microbial burden in aetiology of allergy and asthma
FD Martinez, PG Holt
The Lancet 354, SII12-SII15, 1999
Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity
PA Stumbles, JA Thomas, CL Pimm, PT Lee, TJ Venaille, S Proksch, ...
The Journal of experimental medicine 188 (11), 2019-2031, 1998
Role of respiratory viruses in acute upper and lower respiratory tract illness in the first year of life: a birth cohort study
MMH Kusel, NH de Klerk, PG Holt, T Kebadze, SL Johnston, PD Sly
The Pediatric infectious disease journal 25 (8), 680-686, 2006
Immune and inflammatory function in cigarette smokers.
PG Holt
Thorax 42 (4), 241, 1987
Phenotypic, functional, and plasticity features of classical and alternatively activated human macrophages
AA Tarique, J Logan, E Thomas, PG Holt, PD Sly, E Fantino
American journal of respiratory cell and molecular biology 53 (5), 676-688, 2015
Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfaces.
AS McWilliam, D Nelson, JA Thomas, PG Holt
The Journal of experimental medicine 179 (4), 1331-1336, 1994
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