Andrei Thomas-Tikhonenko
Andrei Thomas-Tikhonenko
University of Pennsylvania & Children's Hospital of Philadelphia
Verified email at
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Widespread microRNA repression by Myc contributes to tumorigenesis
TC Chang, D Yu, YS Lee, EA Wentzel, DE Arking, KM West, CV Dang, ...
Nature genetics 40 (1), 43-50, 2008
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
RK Amaravadi, D Yu, JJ Lum, T Bui, MA Christophorou, GI Evan, ...
The Journal of clinical investigation 117 (2), 326-336, 2007
Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster
M Dews, A Homayouni, D Yu, D Murphy, C Sevignani, E Wentzel, ...
Nature genetics 38 (9), 1060-1065, 2006
Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 ImmunotherapyAlternative Splicing of CD19 Enables Resistance to CART-19
E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ...
Cancer discovery 5 (12), 1282-1295, 2015
Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation
TC Chang, LR Zeitels, HW Hwang, RR Chivukula, EA Wentzel, M Dews, ...
Proceedings of the National Academy of Sciences 106 (9), 3384-3389, 2009
ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth
LS Hart, JT Cunningham, T Datta, S Dey, F Tameire, SL Lehman, BO Qiu, ...
The Journal of clinical investigation 122 (12), 4621-4634, 2012
The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma
P Mestdagh, AK Boström, F Impens, E Fredlund, G Van Peer, ...
Molecular cell 40 (5), 762-773, 2010
The Myc–miR-17∼ 92 Axis Blunts TGFβ Signaling and Production of Multiple TGFβ-Dependent Antiangiogenic FactorsMyc and miR-17∼ 92 Blunt TGFβ Signaling and Antiangiogenesis
M Dews, JL Fox, S Hultine, P Sundaram, W Wang, YY Liu, E Furth, ...
Cancer research 70 (20), 8233-8246, 2010
Direct Repression of FLIP Expression by c-myc Is a Major Determinant of TRAIL Sensitivity
MS Ricci, Z Jin, M Dews, D Yu, A Thomas-Tikhonenko, DT Dicker, ...
Molecular and cellular biology 24 (19), 8541-8555, 2004
Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis
KA O'Donnell, D Yu, KI Zeller, J Kim, F Racke, A Thomas-Tikhonenko, ...
Molecular and cellular biology 26 (6), 2373-2386, 2006
p53-Responsive miR-194 Inhibits Thrombospondin-1 and Promotes Angiogenesis in Colon CancersmiR-194 Regulates Thrombospondin-1 and Angiogenesis
P Sundaram, S Hultine, LM Smith, M Dews, JL Fox, D Biyashev, ...
Cancer research 71 (24), 7490-7501, 2011
B cell–specific loss of histone 3 lysine 9 methylation in the VH locus depends on Pax5
K Johnson, DL Pflugh, D Yu, DGT Hesslein, KI Lin, ALM Bothwell, ...
Nature immunology 5 (8), 853-861, 2004
Metastasis-associated protein 1 (MTA1) is an essential downstream effector of the c-MYC oncoprotein
X Zhang, LM DeSalle, JH Patel, AJ Capobianco, D Yu, ...
Proceedings of the National Academy of Sciences 102 (39), 13968-13973, 2005
Viral Myc oncoproteins in infected fibroblasts down-modulate thrombospondin-1, a possible tumor suppressor gene
AT Tikhonenko, DJ Black, ML Linial
Journal of Biological Chemistry 271 (48), 30741-30747, 1996
An in Vivo Function for the Transforming Myc Protein: Elicitation of the Angiogenic Phenotype
CV Ngo, M Gee, N Akhtar, D Yu, O Volpert, R Auerbach, ...
CD19 is a major B cell receptor–independent activator of MYC-driven B-lymphomagenesis
EY Chung, JN Psathas, D Yu, Y Li, MJ Weiss, A Thomas-Tikhonenko
The Journal of clinical investigation 122 (6), 2257-2266, 2012
Oncogenic BRAF regulates β-Trcp expression and NF-κB activity in human melanoma cells
J Liu, KG Suresh Kumar, D Yu, SA Molton, M McMahon, M Herlyn, ...
Oncogene 26 (13), 1954-1958, 2007
Activation of the myc oncoprotein leads to increased turnover of thrombospondin-1 mRNA
A Janz, C Sevignani, K Kenyon, CV Ngo, A Thomas-Tikhonenko
Nucleic acids research 28 (11), 2268-2275, 2000
Role of GLI2 transcription factor in growth and tumorigenicity of prostate cells
S Thiyagarajan, N Bhatia, S Reagan-Shaw, D Cozma, ...
Cancer Research 67 (22), 10642-10646, 2007
Myc overexpression brings out unexpected antiapoptotic effects of miR-34a
E Sotillo, T Laver, H Mellert, JM Schelter, MA Cleary, S McMahon, ...
Oncogene 30 (22), 2587-2594, 2011
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