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Le Cong 丛乐
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Year
Multiplex genome engineering using CRISPR/Cas systems
L Cong, FA Ran, D Cox, S Lin, R Barretto, N Habib, PD Hsu, X Wu, ...
Science 339 (6121), 819-823, 2013
152912013
In vivo genome editing using Staphylococcus aureus Cas9
F Ran, L Cong, WX Yan, DA Scott, JS Gootenberg, AJ Kriz, B Zetsche, ...
Nature 520 (7546), 186-191, 2015
25342015
MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens
W Li, H Xu, T Xiao, L Cong, MI Love, F Zhang, RA Irizarry, JS Liu, ...
Genome biology 15 (12), 1-12, 2014
12822014
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription
F Zhang, L Cong, S Lodato, S Kosuri, GM Church, P Arlotta
Nature biotechnology 29 (2), 149-153, 2011
11142011
In vivo gene editing in dystrophic mouse muscle and muscle stem cells
M Tabebordbar, K Zhu, JKW Cheng, WL Chew, JJ Widrick, WX Yan, ...
Science 351 (6271), 407-411, 2016
10612016
Optical control of mammalian endogenous transcription and epigenetic states
S Konermann, MD Brigham, AE Trevino, PD Hsu, M Heidenreich, L Cong, ...
Nature 500 (7463), 472-476, 2013
9512013
A transcription activator-like effector toolbox for genome engineering
NE Sanjana, L Cong, Y Zhou, MM Cunniff, G Feng, F Zhang
Nature protocols 7 (1), 171-192, 2012
8832012
Sequence determinants of improved CRISPR sgRNA design
H Xu, T Xiao, CH Chen, W Li, CA Meyer, Q Wu, D Wu, L Cong, F Zhang, ...
Genome research 25 (8), 1147-1157, 2015
5462015
CRISPR-Cas component systems, methods and compositions for sequence manipulation
F Zhang
US Patent 8,795,965, 2014
4482014
CRISPR-Cas component systems, methods and compositions for sequence manipulation
F Zhang
US Patent 8,795,965, 2014
4482014
Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains
L Cong, R Zhou, Y Kuo, M Cunniff, F Zhang
Nature communications 3 (1), 1-6, 2012
4132012
Crystal structure of Staphylococcus aureus Cas9
H Nishimasu, L Cong, WX Yan, FA Ran, B Zetsche, Y Li, A Kurabayashi, ...
Cell 162 (5), 1113-1126, 2015
4022015
Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
F Zhang, L Cong, RJ Platt, NE Sanjana, RAN Fei
US Patent 8,993,233, 2015
3962015
Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
F Zhang, L Cong, RJ Platt, NE Sanjana, RAN Fei
US Patent 8,993,233, 2015
3962015
CRISPR-Cas component systems, methods and compositions for sequence manipulation
L Cong, F Zhang
US Patent 8,871,445, 2014
3532014
Engineering of systems, methods and optimized guide compositions for sequence manipulation
F Zhang, L Cong, P Hsu, RAN Fei
US Patent 8,906,616, 2014
3522014
CRISPR-Cas nickase systems, methods and compositions for sequence manipulation in eukaryotes
L Cong, F Zhang
US Patent 8,932,814, 2015
3492015
CRISPR-Cas nickase systems, methods and compositions for sequence manipulation in eukaryotes
L Cong, F Zhang
US Patent 8,932,814, 2015
3492015
A distinct gene module for dysfunction uncoupled from activation in tumor-infiltrating T cells
M Singer, C Wang, L Cong, ND Marjanovic, MS Kowalczyk, H Zhang, ...
Cell 166 (6), 1500-1511. e9, 2016
3302016
Genome-scale promoter engineering by coselection MAGE
HH Wang, H Kim, L Cong, J Jeong, D Bang, GM Church
Nature methods 9 (6), 591-593, 2012
3012012
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Articles 1–20