mTORC1 and mTORC2 in cancer and the tumor microenvironment LC Kim, RS Cook, J Chen Oncogene 36 (16), 2191-2201, 2017 | 405 | 2017 |
Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer DN Edwards, VM Ngwa, AL Raybuck, S Wang, Y Hwang, LC Kim, SH Cho, ... The Journal of clinical investigation 131 (4), 2021 | 181 | 2021 |
Divergent lncRNA GATA3-AS1 Regulates GATA3 Transcription in T-Helper 2 Cells HR Gibbons, G Shaginurova, LC Kim, N Chapman, CF Spurlock III, ... Frontiers in immunology 9, 2512, 2018 | 104 | 2018 |
The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ DN Edwards, VM Ngwa, S Wang, E Shiuan, DM Brantley-Sieders, LC Kim, ... Science signaling 10 (508), 2017 | 99 | 2017 |
The ephrin-A1/EPHA2 signaling axis regulates glutamine metabolism in HER2-positive breast cancer VM Youngblood, LC Kim, DN Edwards, Y Hwang, PR Santapuram, ... Cancer research 76 (7), 1825-1836, 2016 | 69 | 2016 |
Disruption of the Scaffolding Function of mLST8 Selectively Inhibits mTORC2 Assembly and Function and Suppresses mTORC2-Dependent Tumor Growth In Vivo Y Hwang, LC Kim, W Song, DN Edwards, RS Cook, J Chen Cancer research 79 (13), 3178-3184, 2019 | 50 | 2019 |
GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment R Missiaen, NM Anderson, LC Kim, B Nance, M Burrows, N Skuli, ... Cell metabolism 34 (8), 1151-1167. e7, 2022 | 48 | 2022 |
Hypoxia-inducible factors in cancer LC Kim, MC Simon Cancer research 82 (2), 195-196, 2022 | 24 | 2022 |
Medullary norepinephrine neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis ES Bucher, ME Fox, L Kim, DC Kirkpatrick, NT Rodeberg, AM Belle, ... Journal of Cerebral Blood Flow & Metabolism 34 (7), 1128-1137, 2014 | 23 | 2014 |
Disrupting cellular memory to overcome drug resistance G Harmange, RAR Hueros, DL Schaff, B Emert, M Saint-Antoine, LC Kim, ... Nature communications 14 (1), 7130, 2023 | 18 | 2023 |
ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism S Khare, LC Kim, G Lobel, PT Doulias, H Ischiropoulos, I Nissim, B Keith, ... Cancer & Metabolism 9, 1-16, 2021 | 17 | 2021 |
Phosphorylation of PLCγ1 by EphA2 receptor tyrosine kinase promotes tumor growth in lung cancer W Song, LC Kim, W Han, Y Hou, DN Edwards, S Wang, TS Blackwell, ... Molecular Cancer Research 18 (11), 1735-1743, 2020 | 12 | 2020 |
RICTOR Amplification Promotes NSCLC Cell Proliferation through Formation and Activation of mTORC2 at the Expense of mTORC1 LC Kim, CH Rhee, J Chen Molecular Cancer Research 18 (11), 1675-1684, 2020 | 6 | 2020 |
Divergent lncRNA GATA3-AS1 Regulates GATA3 Transcription in T-Helper 2 Cells. Front Immunol. 2018; 9: 2512 HR Gibbons, G Shaginurova, LC Kim, N Chapman, CF Spurlock 3rd, ... External Resources Crossref (DOI), 2018 | 5 | 2018 |
Fructose-1, 6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness L Gu, Y Zhu, K Watari, M Lee, J Liu, S Perez, M Thai, JE Mayfield, ... Cell metabolism 35 (6), 1009-1021. e9, 2023 | 4 | 2023 |
Regulation of cancer glutamine metabolism by EphA2 RTK-dependent activation of transcriptional co-activators YAP and TAZ DN Edwards, VM Ngwa, S Wang, E Shiuan, D Brantley-Sieders, LC Kim, ... Science signaling 10 (508), 2017 | 1 | 2017 |
Selective targeting of endothelial mTORC1 reduces transendothelial fatty acid delivery to improve anti-tumor immunity and suppress metastatic outgrowth DN Edwards, S Wang, W Song, LC Kim, Y Hwang, J Chen Cancer Research 84 (6_Supplement), 198-198, 2024 | | 2024 |
Cancer Metabolism under Limiting Oxygen Conditions LC Kim, NP Lesner, MC Simon Cold Spring Harbor Perspectives in Medicine 14 (2), a041542, 2024 | | 2024 |
Abstract B051: Investigating lipid homeostasis in pancreatic ductal adenocarcinoma under tumor-like stress X Han, M Burrows, L Kim, C Mesaros, J Tobias, B Keith, C Simon Cancer Research 84 (2_Supplement), B051-B051, 2024 | | 2024 |
Regulation of fatty acid delivery to metastases by tumor endothelium DN Edwards, S Wang, W Song, LC Kim, VM Ngwa, Y Hwang, KC Ess, ... bioRxiv, 2024.04. 02.587724, 2024 | | 2024 |