Carsten Müller-Tidow
Carsten Müller-Tidow
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MALAT-1, a novel noncoding RNA, and thymosin β4 predict metastasis and survival in early-stage non-small cell lung cancer
P Ji, S Diederichs, W Wang, S Böing, R Metzger, PM Schneider, N Tidow, ...
Oncogene 22 (39), 8031-8041, 2003
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
T Schenk, WC Chen, S Göllner, L Howell, L Jin, K Hebestreit, HU Klein, ...
Nature medicine 18 (4), 605-611, 2012
The long noncoding MALAT-1 RNA indicates a poor prognosis in non-small cell lung cancer and induces migration and tumor growth
LH Schmidt, T Spieker, S Koschmieder, J Humberg, D Jungen, E Bulk, ...
Journal of thoracic oncology 6 (12), 1984-1992, 2011
Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival
A Hamilton, GV Helgason, M Schemionek, B Zhang, S Myssina, EK Allan, ...
Blood, The Journal of the American Society of Hematology 119 (6), 1501-1510, 2012
Age-related risk profile and chemotherapy dose response in acute myeloid leukemia: a study by the German Acute Myeloid Leukemia Cooperative Group
T Büchner, WE Berdel, C Haferlach, T Haferlach, S Schnittger, ...
Journal of Clinical Oncology 27 (1), 61-69, 2009
Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells
C Müller-Tidow, B Steffen, T Cauvet, L Tickenbrock, P Ji, S Diederichs, ...
Molecular and cellular biology 24 (7), 2890-2904, 2004
Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2 …
C Röllig, H Serve, A Hüttmann, R Noppeney, C Müller-Tidow, U Krug, ...
The lancet oncology 16 (16), 1691-1699, 2015
Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms
C Polprasert, I Schulze, MA Sekeres, H Makishima, B Przychodzen, ...
Cancer cell 27 (5), 658-670, 2015
Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes
C Choudhary, JV Olsen, C Brandts, J Cox, PNG Reddy, FD Böhmer, ...
Molecular cell 36 (2), 326-339, 2009
Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations
M Mizuki, J Schwäble, C Steur, C Choudhary, S Agrawal, B Sargin, ...
Blood, The Journal of the American Society of Hematology 101 (8), 3164-3173, 2003
Sorafenib in combination with intensive chemotherapy in elderly patients with acute myeloid leukemia: results from a randomized, placebo-controlled trial
H Serve, U Krug, R Wagner, MC Sauerland, A Heinecke, U Brunnberg, ...
Journal of Clinical Oncology 31 (25), 3110-3118, 2013
EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation
GHS Richter, S Plehm, A Fasan, S Rössler, R Unland, IM Bennani-Baiti, ...
Proceedings of the National Academy of Sciences 106 (13), 5324-5329, 2009
Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia
JA Pulikkan, V Dengler, PS Peramangalam, AA Peer Zada, ...
Blood, The Journal of the American Society of Hematology 115 (9), 1768-1778, 2010
Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes
U Krug, C Röllig, A Koschmieder, A Heinecke, MC Sauerland, M Schaich, ...
The Lancet 376 (9757), 2000-2008, 2010
AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations
C Choudhary, J Schwäble, C Brandts, L Tickenbrock, B Sargin, ...
Blood 106 (1), 265-273, 2005
The t (8; 21) fusion protein, AML1–ETO, specifically represses the transcription of the p14ARF tumor suppressor in acute myeloid leukemia
B Linggi, C Müller-Tidow, L Van De Locht, M Hu, J Nip, H Serve, ...
Nature medicine 8 (7), 743-750, 2002
Apolipoprotein E induces antiinflammatory phenotype in macrophages
D Baitsch, HH Bock, T Engel, R Telgmann, C Müller-Tidow, G Varga, ...
Arteriosclerosis, thrombosis, and vascular biology 31 (5), 1160-1168, 2011
Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation
CH Brandts, B Sargin, M Rode, C Biermann, B Lindtner, J Schwäble, ...
Cancer research 65 (21), 9643-9650, 2005
Overexpression of vascular endothelial growth factor (VEGF) and its cellular receptor KDR (VEGFR-2) in the bone marrow of patients with acute myeloid leukemia
T Padro, R Bieker, S Ruiz, M Steins, S Retzlaff, H Bürger, T Büchner, ...
Leukemia 16 (7), 1302-1310, 2002
Flt3-dependent transformation by inactivating c-Cbl mutations in AML
B Sargin, C Choudhary, N Crosetto, MHH Schmidt, R Grundler, ...
Blood, The Journal of the American Society of Hematology 110 (3), 1004-1012, 2007
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