| Rings in drugs: Miniperspective RD Taylor, M MacCoss, ADG Lawson Journal of medicinal chemistry 57 (14), 5845-5859, 2014 | 2042 | 2014 |
| Distinct mechanism for antidepressant activity by blockade of central substance P receptors MS Kramer, N Cutler, J Feighner, R Shrivastava, J Carman, JJ Sramek, ... Science 281 (5383), 1640-1645, 1998 | 1359 | 1998 |
| Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase B Bhat, N Bhat, AB Eldrup, TP Prakash, M Prhavc, Q Song, PD Cook, ... US Patent 7,125,855, 2006 | 491* | 2006 |
| Inhibition of hepatitis C virus RNA replication by 2′-modified nucleoside analogs SS Carroll, JE Tomassini, M Bosserman, K Getty, MW Stahlhut, AB Eldrup, ... Journal of Biological Chemistry 278 (14), 11979-11984, 2003 | 441 | 2003 |
| Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro G Migliaccio, JE Tomassini, SS Carroll, L Tomei, S Altamura, B Bhat, ... Journal of Biological Chemistry 278 (49), 49164-49170, 2003 | 372 | 2003 |
| Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes SD Edmondson, MH Fisher, D Kim, M MacCoss, ER Parmee, AE Weber, ... US Patent 6,699,871, 2004 | 290 | 2004 |
| A 7-deaza-adenosine analog is a potent and selective inhibitor of hepatitis C virus replication with excellent pharmacokinetic properties DB Olsen, AB Eldrup, L Bartholomew, B Bhat, MR Bosserman, A Ceccacci, ... Antimicrobial agents and chemotherapy 48 (10), 3944-3953, 2004 | 278 | 2004 |
| structure− activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase AB Eldrup, CR Allerson, CF Bennett, S Bera, B Bhat, N Bhat, ... Journal of Medicinal Chemistry 47 (9), 2283-2295, 2004 | 260 | 2004 |
| Structural optimization affording 2-(R)-(1-(R)-3, 5-bis (trifluoromethyl) phenylethoxy)-3-(S)-(4-fluoro) phenyl-4-(3-oxo-1, 2, 4-triazol-5-yl) methylmorpholine, a potent … JJ Hale, SG Mills, M MacCoss, PE Finke, MA Cascieri, S Sadowski, E Ber, ... Journal of medicinal chemistry 41 (23), 4607-4614, 1998 | 240 | 1998 |
| Structure−Activity Relationship of Heterobase-Modified 2‘-C-Methyl Ribonucleosides as Inhibitors of Hepatitis C Virus RNA Replication AB Eldrup, M Prhavc, J Brooks, B Bhat, TP Prakash, Q Song, S Bera, ... Journal of medicinal chemistry 47 (21), 5284-5297, 2004 | 237 | 2004 |
| Potent, orally absorbed glucagon receptor antagonists SE de Laszlo, C Hacker, B Li, D Kim, M MacCoss, N Mantlo, JV Pivnichny, ... Bioorganic & medicinal chemistry letters 9 (5), 641-646, 1999 | 218 | 1999 |
| Anthrax lethal factor inhibition WL Shoop, Y Xiong, J Wiltsie, A Woods, J Guo, JV Pivnichny, T Felcetto, ... Proceedings of the National Academy of Sciences 102 (22), 7958-7963, 2005 | 217 | 2005 |
| The novel NK1 receptor antagonist MK–0869 (L–754,030) and its water soluble phosphoryl prodrug, L–758,298, inhibit acute and delayed cisplatin-induced emesis in ferrets FD Tattersall, W Rycroft, M Cumberbatch, G Mason, S Tye, DJ Williamson, ... Neuropharmacology 39 (4), 652-663, 2000 | 170 | 2000 |
| Potent 1, 3, 4-trisubstituted pyrrolidine CCR5 receptor antagonists: effects of fused heterocycles on antiviral activity and pharmacokinetic properties D Kim, L Wang, JJ Hale, CL Lynch, RJ Budhu, M MacCoss, SG Mills, ... Bioorganic & medicinal chemistry letters 15 (8), 2129-2134, 2005 | 168 | 2005 |
| Pyrroles and other heterocycles as inhibitors of p38 kinase SE de Laszlo, D Visco, L Agarwal, L Chang, J Chin, G Croft, A Forsyth, ... Bioorganic & medicinal chemistry letters 8 (19), 2689-2694, 1998 | 162 | 1998 |
| Organic chemistry in drug discovery M MacCoss, TA Baillie Science 303 (5665), 1810-1813, 2004 | 153 | 2004 |
| Substituted imidazoles as glucagon receptor antagonists LL Chang, KL Sidler, MA Cascieri, S de Laszlo, G Koch, B Li, M MacCoss, ... Bioorganic & medicinal chemistry letters 11 (18), 2549-2553, 2001 | 152 | 2001 |
| Morpholine and thiomorpholine tachykinin receptor antagonists CP Dorn, PE Finke, JJ Hale, M MacCoss, SG Mills, SK Shah, ... US Patent 5,719,147, 1998 | 146 | 1998 |
| Modification of the Dittmer-Lester reagent for the detection of phospholipid derivatives on thin-layer chromatograms. EK Ryu, M MacCoss Journal of lipid research 20 (4), 561-563, 1979 | 145 | 1979 |
| Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 4: synthesis and structure–Activity relationships for 1-[N-(Methyl)-N-(phenylsulfonyl) amino]-2-(phenyl)-4-(4 … PE Finke, B Oates, SG Mills, M MacCoss, L Malkowitz, MS Springer, ... Bioorganic & medicinal chemistry letters 11 (18), 2475-2479, 2001 | 135 | 2001 |
