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Simone Bido
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Pharmacological inhibition of necroptosis protects from dopaminergic neuronal cell death in Parkinson’s disease models
A Iannielli, S Bido, L Folladori, A Segnali, C Cancellieri, A Maresca, ...
Cell reports 22 (8), 2066-2079, 2018
1882018
dCas9-based Scn1a gene activation restores inhibitory interneuron excitability and attenuates seizures in Dravet syndrome mice
G Colasante, G Lignani, S Brusco, C Di Berardino, J Carpenter, ...
Molecular Therapy 28 (1), 235-253, 2020
1682020
Nanoparticulate lipid dispersions for bromocriptine delivery: Characterization and in vivo study
E Esposito, P Mariani, L Ravani, C Contado, M Volta, S Bido, M Drechsler, ...
European journal of pharmaceutics and biopharmaceutics 80 (2), 306-314, 2012
1322012
Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression
M Bourdenx, S Dovero, M Engeln, S Bido, MF Bastide, N Dutheil, ...
Acta neuropathologica communications 3, 1-15, 2015
1202015
AAV-PHP. B-mediated global-scale expression in the mouse nervous system enables GBA1 gene therapy for wide protection from synucleinopathy
G Morabito, SG Giannelli, G Ordazzo, S Bido, V Castoldi, M Indrigo, ...
Molecular Therapy 25 (12), 2727-2742, 2017
1162017
Targeting β-arrestin2 in the treatment of l-DOPA–induced dyskinesia in Parkinson’s disease
NM Urs, S Bido, SM Peterson, TL Daigle, CE Bass, RR Gainetdinov, ...
Proceedings of the National Academy of Sciences 112 (19), E2517-E2526, 2015
1122015
Mitochondrial division inhibitor-1 is neuroprotective in the A53T-α-synuclein rat model of Parkinson’s disease
S Bido, FN Soria, RZ Fan, E Bezard, K Tieu
Scientific reports 7 (1), 7495, 2017
1082017
Amantadine attenuates levodopa‐induced dyskinesia in mice and rats preventing the accompanying rise in nigral GABA levels
S Bido, M Marti, M Morari
Journal of neurochemistry 118 (6), 1043-1055, 2011
1002011
Microglia-specific overexpression of α-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity
S Bido, S Muggeo, L Massimino, MJ Marzi, SG Giannelli, E Melacini, ...
Nature communications 12 (1), 6237, 2021
902021
In vivo evidence for a differential contribution of striatal and nigral D1 and D2 receptors to L-DOPA induced dyskinesia and the accompanying surge of nigral amino acid levels
F Mela, M Marti, S Bido, MA Cenci, M Morari
Neurobiology of disease 45 (1), 573-582, 2012
802012
Reconstitution of the human nigro-striatal pathway on-a-chip reveals OPA1-dependent mitochondrial defects and loss of dopaminergic synapses
A Iannielli, GS Ugolini, C Cordiglieri, S Bido, A Rubio, G Colasante, ...
Cell reports 29 (13), 4646-4656. e4, 2019
422019
Scn1a gene reactivation after symptom onset rescues pathological phenotypes in a mouse model of Dravet syndrome
N Valassina, S Brusco, A Salamone, L Serra, M Luoni, S Giannelli, S Bido, ...
Nature communications 13 (1), 161, 2022
392022
Further evidence for an involvement of nociceptin/orphanin FQ in the pathophysiology of Parkinson’s disease: a behavioral and neurochemical study in reserpinized mice
M Volta, OS Mabrouk, S Bido, M Marti, M Morari
Journal of neurochemistry 115 (6), 1543-1555, 2010
312010
Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson's disease
L Arcuri, R Viaro, S Bido, F Longo, M Calcagno, PO Fernagut, NT Zaveri, ...
Neurobiology of disease 89, 55-64, 2016
272016
Differential involvement of Ras‐GRF1 and Ras‐GRF2 in L‐DOPA‐induced dyskinesia
S Bido, N Solari, M Indrigo, A D'Antoni, R Brambilla, M Morari, S Fasano
Annals of Clinical and Translational Neurology 2 (6), 662-678, 2015
222015
Ablation of the tail of the ventral tegmental area compensates symptoms in an experimental model of Parkinson's disease
F Faivre, MJ Sánchez-Catalán, S Dovero, S Bido, A Joshi, E Bezard, ...
Neurobiology of Disease 139, 104818, 2020
162020
Selective homing of CAR-CIK cells to the bone marrow niche enhances control of the acute myeloid leukemia burden
M Biondi, S Tettamanti, S Galimberti, B Cerina, C Tomasoni, R Piazza, ...
Blood, The Journal of the American Society of Hematology 141 (21), 2587-2598, 2023
132023
Mol Ther. Dec. 6, 2017; 25 (12): 2727-2742
G Morabito, SG Giannelli, G Ordazzo, S Bido, V Castoldi, M Indrigo, ...
Epub Aug 10, 2017
112017
D1 dopamine receptor stimulation impairs striatal proteasome activity in Parkinsonism through 26S proteasome disassembly
P Barroso-Chinea, ML Thiolat, S Bido, A Martinez, E Doudnikoff, ...
Neurobiology of disease 78, 77-87, 2015
112015
A SOX2-engineered epigenetic silencer factor represses the glioblastoma genetic program and restrains tumor development
V Benedetti, F Banfi, M Zaghi, R Moll-Diaz, L Massimino, L Argelich, ...
Science advances 8 (31), eabn3986, 2022
92022
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