| Directed Evolution of Protein Catalysts C Zeymer, D Hilvert Annual Review of Biochemistry 87, 131-157, 2018 | 406 | 2018 |
| Efficient laboratory evolution of computationally designed enzymes with low starting activities using fluorescence-activated droplet sorting R Obexer, M Pott, C Zeymer, AD Griffiths, D Hilvert Protein Engineering, Design and Selection 29 (9), 355-366, 2016 | 90 | 2016 |
| Optimization of Enzyme Mechanism along the Evolutionary Trajectory of a Computationally Designed (Retro-) Aldolase C Zeymer, R Zschoche, D Hilvert Journal of the American Chemical Society 139 (36), 12541-12549, 2017 | 50 | 2017 |
| Lysine acylation using conjugating enzymes for site-specific modification and ubiquitination of recombinant proteins R Hofmann, G Akimoto, TG Wucherpfennig, C Zeymer, JW Bode Nature Chemistry 12 (11), 1008–1015, 2020 | 45 | 2020 |
| Emergence of a negative activation heat capacity during evolution of a designed enzyme HA Bunzel, H Kries, L Marchetti, C Zeymer, P Mittl, AJ Mulholland, ... Journal of the American Chemical Society 141 (30), 11745-11748, 2019 | 45 | 2019 |
| Bap (Sil1) regulates the molecular chaperone BiP by coupling release of nucleotide and substrate M Rosam, D Krader, C Nickels, J Hochmair, KC Back, G Agam, A Barth, ... Nature Structural & Molecular Biology 25 (1), 90-100, 2018 | 45 | 2018 |
| Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion SJ Caldwell, IC Haydon, N Piperidou, PS Huang, MJ Bick, HS Sjöström, ... Proceedings of the National Academy of Sciences 117 (48), 30362-30369, 2020 | 40 | 2020 |
| RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase Clp1 A Dikfidan, B Loll, C Zeymer, I Magler, T Clausen, A Meinhart Molecular Cell 54 (6), 975-986, 2014 | 34 | 2014 |
| trans-Acting arginine residues in the AAA+ chaperone ClpB allosterically regulate the activity through inter-and intradomain communication C Zeymer, S Fischer, J Reinstein Journal of Biological Chemistry 289 (47), 32965-32976, 2014 | 26 | 2014 |
| Elements in nucleotide sensing and hydrolysis of the AAA+ disaggregation machine ClpB: a structure-based mechanistic dissection of a molecular motor C Zeymer, TRM Barends, ND Werbeck, I Schlichting, J Reinstein Acta Crystallographica Section D: Biological Crystallography 70 (2), 582-595, 2014 | 26 | 2014 |
| Characterizing Active Site Conformational Heterogeneity along the Trajectory of an Enzymatic Phosphoryl Transfer Reaction C Zeymer, ND Werbeck, S Zimmermann, J Reinstein, DF Hansen Angewandte Chemie Int Ed Engl 55 (38), 11533-11537, 2016 | 23 | 2016 |
| Americium preferred: lanmodulin, a natural lanthanide-binding protein, favors an actinide over lanthanides H Singer, B Drobot, C Zeymer, R Steudtner, LJ Daumann Chemical Science 12, 15581-15587, 2021 | 21 | 2021 |
| The molecular mechanism of Hsp100 chaperone inhibition by the prion curing agent guanidinium chloride C Zeymer, ND Werbeck, I Schlichting, J Reinstein Journal of Biological Chemistry 288 (10), 7065-7076, 2013 | 21 | 2013 |
| A sterile α-motif domain in NafY targets apo-NifDK for iron-molybdenum cofactor delivery via a tethered domain JA Hernandez, AH Phillips, WK Erbil, D Zhao, M Demuez, C Zeymer, ... Journal of Biological Chemistry 286 (8), 6321-6328, 2011 | 21 | 2011 |
| Design and engineering of artificial metalloproteins: from de novo metal coordination to catalysis AS Klein, C Zeymer Protein Engineering, Design and Selection 34, gzab003, 2021 | 19 | 2021 |
| Coupling of oligomerization and nucleotide binding in the AAA+ chaperone ClpB ND Werbeck, C Zeymer, JN Kellner, J Reinstein Biochemistry 50 (5), 899-909, 2011 | 18 | 2011 |
| Minor Actinides Can Replace Essential Lanthanides in Bacterial Life H Singer, R Steudtner, AS Klein, C Rulofs, C Zeymer, B Drobot, A Pol, ... Angewandte Chemie International Edition 62, e202303669, 2023 | 6* | 2023 |
| Analysis of electrostatic coupling throughout the laboratory evolution of a designed retroaldolase TA Coulther, M Pott, C Zeymer, D Hilvert, MJ Ondrechen Protein Science 30, 1617-1627, 2021 | 5 | 2021 |
| Book Review: "Directed Evolution of Selective Enzymes: Catalysts for Organic Chemistry and Biotechnology" by Manfred T. Reetz C Zeymer ChemBioChem 20 (3), 415-416, 2019 | 3 | 2019 |
| A de novo metalloenzyme for cerium photoredox catalysis AS Klein, F Leiss-Maier, R Mühlhofer, B Boesen, G Mustafa, H Kugler, ... ChemRxiv, 2024 | | 2024 |
