Complete removal of extracellular IgG antibodies in a randomized dose-escalation phase I study with the bacterial enzyme IdeS–a novel therapeutic opportunity L Winstedt, S Järnum, EA Nordahl, A Olsson, A Runström, R Bockermann, ... PLoS One 10 (7), e0132011, 2015 | 158 | 2015 |
Antibody orientation at bacterial surfaces is related to invasive infection P Nordenfelt, S Waldemarson, A Linder, M Mörgelin, C Karlsson, ... Journal of Experimental Medicine 209 (13), 2367-2381, 2012 | 129 | 2012 |
Proteins of novel lactic acid bacteria from Apis mellifera mellifera: an insight into the production of known extra-cellular proteins during microbial stress È Butler, M Alsterfjord, TC Olofsson, C Karlsson, J Malmström, A Vásquez BMC microbiology 13, 1-12, 2013 | 102 | 2013 |
Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis T Mohanty, J Fisher, A Bakochi, A Neumann, JFP Cardoso, CAQ Karlsson, ... Nature communications 10 (1), 1667, 2019 | 90 | 2019 |
Proteome-wide selected reaction monitoring assays for the human pathogen Streptococcus pyogenes C Karlsson, L Malmström, R Aebersold, J Malmström Nature communications 3 (1), 1301, 2012 | 76 | 2012 |
Proteome profiling of recombinant DNase therapy in reducing NETs and aiding recovery in COVID-19 patients J Fisher, T Mohanty, CAQ Karlsson, SMH Khademi, E Malmström, ... Molecular & Cellular Proteomics 20, 2021 | 62 | 2021 |
SufA–a novel subtilisin-like serine proteinase of Finegoldia magna C Karlsson, ML Andersson, M Collin, A Schmidtchen, L Björck, IM Frick Microbiology 153 (12), 4208-4218, 2007 | 59 | 2007 |
A comprehensive analysis of the Streptococcus pyogenes and human plasma protein interaction network K Sjöholm, C Karlsson, A Linder, J Malmström Molecular BioSystems 10 (7), 1698-1708, 2014 | 54 | 2014 |
Streptococcus pyogenes in human plasma: adaptive mechanisms analyzed by mass spectrometry-based proteomics J Malmström, C Karlsson, P Nordenfelt, R Ossola, H Weisser, A Quandt, ... Journal of Biological Chemistry 287 (2), 1415-1425, 2012 | 51 | 2012 |
A quantitative Streptococcus pyogenes–human protein–protein interaction map reveals localization of opsonizing antibodies L Happonen, S Hauri, G Svensson Birkedal, C Karlsson, T de Neergaard, ... Nature communications 10 (1), 2727, 2019 | 49 | 2019 |
Identification of a novel protein promoting the colonization and survival of Finegoldia magna, a bacterial commensal and opportunistic pathogen IM Frick, C Karlsson, M Mörgelin, AI Olin, R Janjusevic, C Hammarström, ... Molecular microbiology 70 (3), 695-708, 2008 | 43 | 2008 |
Streptococcus pyogenes evades adaptive immunity through specific IgG glycan hydrolysis A Naegeli, E Bratanis, C Karlsson, O Shannon, R Kalluru, A Linder, ... Journal of Experimental Medicine 216 (7), 1615-1629, 2019 | 37 | 2019 |
Automated selected reaction monitoring software for accurate label-free protein quantification J Teleman, C Karlsson, S Waldemarson, K Hansson, P James, ... Journal of proteome research 11 (7), 3766-3773, 2012 | 37 | 2012 |
SufA of the opportunistic pathogen Finegoldia magna modulates actions of the antibacterial chemokine MIG/CXCL9, promoting bacterial survival during epithelial inflammation C Karlsson, M Eliasson, AI Olin, M Mörgelin, A Karlsson, M Malmsten, ... Journal of biological chemistry 284 (43), 29499-29508, 2009 | 37 | 2009 |
The TLR2 antagonist staphylococcal superantigen-like protein 3 acts as a virulence factor to promote bacterial pathogenicity in vivo KJ Koymans, O Goldmann, CAQ Karlsson, W Sital, R Thänert, A Bisschop, ... Journal of innate immunity 9 (6), 561-573, 2017 | 33 | 2017 |
Quantitative proteogenomics of human pathogens using DIA-MS L Malmström, A Bakochi, G Svensson, O Kilsgård, H Lantz, AC Petersson, ... Journal of proteomics 129, 98-107, 2015 | 30 | 2015 |
SufA–a bacterial enzyme that cleaves fibrinogen and blocks fibrin network formation C Karlsson, M Morgelin, M Collin, R Lood, ML Andersson, A Schmidtchen, ... Microbiology 155 (1), 238-248, 2009 | 28 | 2009 |
Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis in a murine lung fibrosis model L Tanner, AB Single, RKV Bhongir, M Heusel, T Mohanty, CAQ Karlsson, ... Nature communications 14 (1), 643, 2023 | 24 | 2023 |
Streptococcus pyogenes infection and the human proteome with a special focus on the immunoglobulin G-cleaving enzyme IdeS CAQ Karlsson, S Järnum, L Winstedt, C Kjellman, L Björck, A Linder, ... Molecular & Cellular Proteomics 17 (6), 1097-1111, 2018 | 24 | 2018 |
Streptococcal inhibitor of complement (SIC) modulates fibrinolysis and enhances bacterial survival within fibrin clots IM Frick, O Shannon, A Neumann, C Karlsson, M Wikström, L Björck Journal of Biological Chemistry 293 (35), 13578-13591, 2018 | 22 | 2018 |