A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation CK Kaufman, C Mosimann, ZP Fan, S Yang, AJ Thomas, J Ablain, JL Tan, ... Science 351 (6272), aad2197, 2016 | 382 | 2016 |
Stress from nucleotide depletion activates the transcriptional regulator HEXIM1 to suppress melanoma JL Tan, RD Fogley, RA Flynn, J Ablain, S Yang, V Saint-André, ZP Fan, ... Molecular cell 62 (1), 34-46, 2016 | 79 | 2016 |
Chemical screening in zebrafish for novel biological and therapeutic discovery JL Tan, LI Zon Methods in cell biology 105, 491-516, 2011 | 67 | 2011 |
New high-throughput screening identifies compounds that reduce viability specifically in liver cancer cells that express high levels of SALL4 by inhibiting oxidative … JL Tan, F Li, JZ Yeo, KJ Yong, MA Bassal, GH Ng, MY Lee, CY Leong, ... Gastroenterology 157 (6), 1615-1629. e17, 2019 | 46 | 2019 |
Monitoring structural modulation of redox-sensitive proteins in cells with MS-CETSA W Sun, L Dai, H Yu, B Puspita, T Zhao, F Li, JL Tan, YT Lim, MW Chen, ... Redox biology 24, 101168, 2019 | 41 | 2019 |
Metabolic alterations and vulnerabilities in hepatocellular carcinoma DG Tenen, L Chai, JL Tan Gastroenterology Report 9 (1), 1-13, 2021 | 37 | 2021 |
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation. Science 351: aad2197 CK Kaufman, C Mosimann, ZP Fan, S Yang, AJ Thomas, J Ablain, JL Tan, ... | 6 | 2016 |
Targeting transcription factors through an IMiD independent zinc finger domain BH Liu, M Liu, S Radhakrishnan, CK Jaladanki, C Gao, J Tang, K Kumari, ... bioRxiv, 2024.01. 03.574032, 2024 | | 2024 |
Targeting the Oncofetal Transcription Factor Protein SALL4 in Cancer By a Non-IMiD Degrader KAL Vu, K Kumari, BH Liu, C Gao, F Li, JP Tang, D Maddalo, X Tian, ... Blood 142, 7144, 2023 | | 2023 |
SALL4B, not targeted by IMiD, is important for SALL4-mediated tumorigenesis KAL Vu, K Kumari, BH Liu, C Gao, F Li, J Tang, D Maddalo, D Auld, ... bioRxiv, 2023.07. 07.548071, 2023 | | 2023 |
A high-throughput chemical genetic screen reveals SALL4-induced metabolic vulnerabilities in cancer JL Tan, F Li, JZ Yeo, KJ Yong, MA Bassal, GH Ng, MY Lee, CY Leong, ... Cancer Research 80 (16_Supplement), 1788-1788, 2020 | | 2020 |
Abstract PR06: The reemergence of neural crest progenitor identity is a key event in the initiation of melanoma from a field of cancer-prone melanocytes CK Kaufman, C Mosimann, A Thomas, ZP Fan, S Yang, J Tan, RD Fogley, ... Molecular Cancer Research 14 (4_Supplement), PR06-PR06, 2016 | | 2016 |
The Role of HEXIM1 in the Transcriptional Regulation of Neural Crest Differentiation and Melanoma JLH Tan | | 2014 |