DNA methylation signatures link prenatal famine exposure to growth and metabolism EW Tobi, JJ Goeman, R Monajemi, H Gu, H Putter, Y Zhang, RC Slieker, ... Nature communications 5 (1), 5592, 2014 | 624 | 2014 |
The power of genetic diversity in genome-wide association studies of lipids SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ... Nature 600 (7890), 675-679, 2021 | 510 | 2021 |
Disease variants alter transcription factor levels and methylation of their binding sites MJ Bonder, R Luijk, DV Zhernakova, M Moed, P Deelen, M Vermaat, ... Nature genetics 49 (1), 131-138, 2017 | 468 | 2017 |
Human-iPSC-derived cardiac stromal cells enhance maturation in 3D cardiac microtissues and reveal non-cardiomyocyte contributions to heart disease E Giacomelli, V Meraviglia, G Campostrini, A Cochrane, X Cao, ... Cell stem cell 26 (6), 862-879. e11, 2020 | 449 | 2020 |
A saturated map of common genetic variants associated with human height L Yengo, S Vedantam, E Marouli, J Sidorenko, E Bartell, S Sakaue, ... Nature 610 (7933), 704-712, 2022 | 419 | 2022 |
A reference map of potential determinants for the human serum metabolome N Bar, T Korem, O Weissbrod, D Zeevi, D Rothschild, S Leviatan, ... Nature 588 (7836), 135-140, 2020 | 324 | 2020 |
DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood EW Tobi, RC Slieker, R Luijk, KF Dekkers, AD Stein, KM Xu, ... Science advances 4 (1), eaao4364, 2018 | 284 | 2018 |
Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array RC Slieker, SD Bos, JJ Goeman, JVMG Bovée, RP Talens, ... Epigenetics & chromatin 6, 1-12, 2013 | 267 | 2013 |
Zebrafish as potential model for developmental neurotoxicity testing: a mini review C De Esch, R Slieker, A Wolterbeek, R Woutersen, D de Groot Neurotoxicology and teratology 34 (6), 545-553, 2012 | 229 | 2012 |
Blood lipids influence DNA methylation in circulating cells KF Dekkers, M van Iterson, RC Slieker, MH Moed, MJ Bonder, ... Genome biology 17, 1-12, 2016 | 195 | 2016 |
MethylAid: visual and interactive quality control of large Illumina 450k datasets M Van Iterson, EW Tobi, RC Slieker, W Den Hollander, R Luijk, ... Bioinformatics 30 (23), 3435-3437, 2014 | 176 | 2014 |
Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome EW Tobi, RC Slieker, AD Stein, HED Suchiman, PE Slagboom, ... International journal of epidemiology 44 (4), 1211-1223, 2015 | 173 | 2015 |
Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception RC Slieker, CL Relton, TR Gaunt, PE Slagboom, BT Heijmans Epigenetics & chromatin 11, 1-11, 2018 | 162 | 2018 |
Alternative routes to induce naive pluripotency in human embryonic stem cells G Duggal, S Warrier, S Ghimire, D Broekaert, M Van der Jeught, ... Stem cells 33 (9), 2686-2698, 2015 | 144 | 2015 |
Locomotor activity assay in zebrafish larvae: influence of age, strain and ethanol C de Esch, H van der Linde, R Slieker, R Willemsen, A Wolterbeek, ... Neurotoxicology and teratology 34 (4), 425-433, 2012 | 143 | 2012 |
Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms RC Slieker, M van Iterson, R Luijk, M Beekman, DV Zhernakova, ... Genome biology 17, 1-13, 2016 | 141 | 2016 |
DNA methylation landscapes of human fetal development RC Slieker, MS Roost, L van Iperen, HED Suchiman, EW Tobi, F Carlotti, ... PLoS genetics 11 (10), e1005583, 2015 | 99 | 2015 |
Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER HED Suchiman, RC Slieker, D Kremer, PE Slagboom, BT Heijmans, ... Frontiers in genetics 6, 287, 2015 | 97 | 2015 |
Early-and late-onset preeclampsia and the tissue-specific epigenome of the placenta and newborn EM Herzog, AJ Eggink, SP Willemsen, RC Slieker, KPJ Wijnands, JF Felix, ... Placenta 58, 122-132, 2017 | 80 | 2017 |
Systemic Age-Associated DNA Hypermethylation of ELOVL2 Gene: In Vivo and In Vitro Evidences of a Cell Replication Process MG Bacalini, J Deelen, C Pirazzini, M De Cecco, C Giuliani, C Lanzarini, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2017 | 78 | 2017 |