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Elizabeth S Silagi
Elizabeth S Silagi
Havard Medical School
Verified email at hms.harvard.edu
Title
Cited by
Cited by
Year
A novel mouse model of intervertebral disc degeneration shows altered cell fate and matrix homeostasis
H Choi, S Tessier, ES Silagi, R Kyada, F Yousefi, N Pleshko, IM Shapiro, ...
Matrix Biology 70, 102-122, 2018
1162018
Glycosaminoglycan synthesis in the nucleus pulposus: dysregulation and the pathogenesis of disc degeneration
ES Silagi, IM Shapiro, MV Risbud
Matrix Biology 71, 368-379, 2018
1112018
Hypoxic regulation of mitochondrial metabolism and mitophagy in nucleus pulposus cells is dependent on HIF‐1α–BNIP3 axis
V Madhu, PK Boneski, E Silagi, Y Qiu, I Kurland, AR Guntur, IM Shapiro, ...
Journal of Bone and Mineral Research 35 (8), 1504-1524, 2020
832020
Bicarbonate recycling by HIF‐1–dependent carbonic anhydrase isoforms 9 and 12 is critical in maintaining intracellular pH and viability of nucleus pulposus cells
ES Silagi, ZR Schoepflin, EL Seifert, C Merceron, E Schipani, IM Shapiro, ...
Journal of bone and Mineral Research 33 (2), 338-355, 2018
572018
Lactate efflux from intervertebral disc cells is required for maintenance of spine health
ES Silagi, EJ Novais, S Bisetto, AG Telonis, J Snuggs, CL Le Maitre, Y Qiu, ...
Journal of Bone and Mineral Research 35 (3), 550-570, 2020
562020
The role of HIF proteins in maintaining the metabolic health of the intervertebral disc
ES Silagi, E Schipani, IM Shapiro, MV Risbud
Nature Reviews Rheumatology 17 (7), 426-439, 2021
512021
Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival
Y Fukuda, MF Pazyra-Murphy, ES Silagi, OE Tasdemir-Yilmaz, Y Li, ...
Journal of Cell Biology 220 (1), e202005051, 2020
492020
Expression of carbonic anhydrase III, a nucleus pulposus phenotypic marker, is hypoxia-responsive and confers protection from oxidative stress-induced cell death
ES Silagi, P Batista, IM Shapiro, MV Risbud
Scientific Reports 8 (1), 4856, 2018
412018
Circadian factors BMAL1 and RORα control HIF-1α transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health
K Suyama, ES Silagi, H Choi, K Sakabe, J Mochida, IM Shapiro, ...
Oncotarget 7 (17), 23056, 2016
412016
PHD3 is a transcriptional coactivator of HIF-1α in nucleus pulposus cells independent of the PKM2-JMJD5 axis
ZR Schoepflin, ES Silagi, IM Shapiro, MV Risbud
The FASEB Journal 31 (9), 3831, 2017
262017
GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc
SN Johnston, ES Silagi, V Madhu, DH Nguyen, IM Shapiro, MV Risbud
JCI insight 8 (8), 2023
52023
Uncomfortably numb: how Nav1.7 mediates paclitaxel-induced peripheral neuropathy
ES Silagi, RA Segal
Brain 144 (6), 1621-1623, 2021
32021
Hypoxia and HIFs maintain the metabolic health of cells of the intervertebral disc
ES Silagi, E Schipani, IM Shapiro, MV Risbud
Nature reviews. Rheumatology 17 (7), 426, 2021
12021
Insights into Glycolytic Metabolism and pH Homeostasis in the Hypoxic Intervertebral Disc
ES Silagi
Thomas Jefferson University, 2019
2019
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