An externally tunable bacterial band-pass filter T Sohka, RA Heins, RM Phelan, JM Greisler, CA Townsend, M Ostermeier Proceedings of the National Academy of Sciences 106 (25), 10135-10140, 2009 | 206 | 2009 |
Engineering Terpene Biosynthesis in Streptomyces for Production of the Advanced Biofuel Precursor Bisabolene RM Phelan, ON Sekurova, JD Keasling, SB Zotchev ACS Synthetic Biology 4 (4), 393-399, 2015 | 78 | 2015 |
Development of Next Generation Synthetic Biology Tools for Use in Streptomyces venezuelae RM Phelan, D Sachs, SJ Petkiewicz, JF Barajas, JM Blake-Hedges, ... ACS synthetic biology 6 (1), 159-166, 2017 | 76 | 2017 |
Comprehensive structural and biochemical analysis of the terminal myxalamid reductase domain for the engineered production of primary alcohols JF Barajas, RM Phelan, AJ Schaub, JT Kliewer, PJ Kelly, DR Jackson, ... Chemistry & biology 22 (8), 1018-1029, 2015 | 62 | 2015 |
Production of Odd-Carbon Dicarboxylic Acids in Escherichia coli Using an Engineered Biotin–Fatty Acid Biosynthetic Pathway RW Haushalter, RM Phelan, KM Hoh, C Su, G Wang, EEK Baidoo, ... Journal of the American Chemical Society 139 (13), 4615-4618, 2017 | 40 | 2017 |
Mechanistic insights into the bifunctional non-heme iron oxygenase carbapenem synthase by active site saturation mutagenesis RM Phelan, CA Townsend Journal of the American Chemical Society 135 (20), 7496-7502, 2013 | 40 | 2013 |
Definition of the Common and Divergent Steps in Carbapenem β‐Lactam Antibiotic Biosynthesis MJ Bodner, R Li, RM Phelan, MF Freeman, KA Moshos, EP Lloyd, ... ChemBioChem 12 (14), 2159-2165, 2011 | 37 | 2011 |
Design and synthesis of a β-lactamase activated 5-fluorouracil prodrug RM Phelan, M Ostermeier, CA Townsend Bioorganic & medicinal chemistry letters 19 (4), 1261-1263, 2009 | 37 | 2009 |
Non-heme iron oxygenases generate natural structural diversity in carbapenem antibiotics MJ Bodner, RM Phelan, MF Freeman, R Li, CA Townsend Journal of the American Chemical Society 132 (1), 12-13, 2010 | 35 | 2010 |
In vitro Characterization of Phenylacetate Decarboxylase, a Novel Enzyme Catalyzing Toluene Biosynthesis in an Anaerobic Microbial Community K Zargar, R Saville, RM Phelan, SG Tringe, CJ Petzold, JD Keasling, ... Scientific reports 6 (1), 31362, 2016 | 34 | 2016 |
Divergent Mechanistic Routes for the Formation of gem‐Dimethyl Groups in the Biosynthesis of Complex Polyketides S Poust, RM Phelan, K Deng, L Katz, CJ Petzold, JD Keasling Angewandte Chemie International Edition 54 (8), 2370-2373, 2015 | 33 | 2015 |
A catalytic asymmetric route to carbapenems MJ Bodner, RM Phelan, CA Townsend Organic letters 11 (16), 3606-3609, 2009 | 32 | 2009 |
A high-throughput screen for the engineered production of β-lactam antibiotics RM Phelan, BJ DiPardo, CA Townsend ACS Chemical Biology 7 (5), 835-840, 2012 | 19 | 2012 |
Development of scalable processes with underutilized biocatalyst classes RM Phelan, MJ Abrahamson, JTC Brown, RK Zhang, CR Zwick III Organic Process Research & Development 26 (7), 1944-1959, 2022 | 4 | 2022 |
Solid, Noncovalent Formulation of Biocatalysts for Rapid and Accurate Submilligram Dosing to Microtiter Plates JTC Brown, NP Tu, RM Phelan Organic Process Research & Development 25 (2), 337-341, 2021 | 3 | 2021 |
Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds AL Ramos, ER Goedken, KE Frank, MA Argiriadi, S Bazzaz, Z Bian, ... Journal of Medicinal Chemistry, 2024 | | 2024 |
Comparison of Diverse Amine Donors for Use in the High-Throughput Screening of Amine Transaminases JTC Brown, RM Phelan Organic Process Research & Development 27 (7), 1293-1299, 2023 | | 2023 |
Characterization of an ECF56-family sigma factor from Streptomyces venezuelae reveals a highly conserved regulome MG Thompson, A Zargar, P Cruz-Morales, T De Rond, S Chang, ... bioRxiv, 2020.01. 30.927608, 2020 | | 2020 |
Method for late introduction of the (8R) hydroxyl group carbapenem β-lactam antibiotic synthesis CA Townsend, MJ Bodner, RM Phelan, MF Freeman US Patent 9,458,479, 2016 | | 2016 |
Method for late introduction of the (8R)-hydroxyl group carbapenem β-lactam antibiotic synthesis CA Townsend, MJ Bodner, RM Phelan, MF Freeman US Patent 9,139,588, 2015 | | 2015 |