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Chunlong Ma
Chunlong Ma
Research specialist
Verified email at pharmacy.arizona.edu
Title
Cited by
Cited by
Year
Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease
C Ma, MD Sacco, B Hurst, JA Townsend, Y Hu, T Szeto, X Zhang, ...
Cell research 30 (8), 678-692, 2020
7312020
Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against Mpro and cathepsin L
MD Sacco, C Ma, P Lagarias, A Gao, JA Townsend, X Meng, P Dube, ...
Science Advances 6 (50), eabe0751, 2020
3322020
Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus
J Wang, Y Wu, C Ma, G Fiorin, J Wang, LH Pinto, RA Lamb, ML Klein, ...
Proceedings of the National Academy of Sciences 110 (4), 1315-1320, 2013
2552013
Ebselen, disulfiram, carmofur, PX-12, tideglusib, and shikonin are nonspecific promiscuous SARS-CoV-2 main protease inhibitors
C Ma, Y Hu, JA Townsend, PI Lagarias, MT Marty, A Kolocouris, J Wang
ACS pharmacology & translational science 3 (6), 1265-1277, 2020
2152020
Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel
X Jing, C Ma, Y Ohigashi, FA Oliveira, TS Jardetzky, LH Pinto, RA Lamb
Proceedings of the National Academy of Sciences 105 (31), 10967-10972, 2008
2152008
Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19
B Boras, RM Jones, BJ Anson, D Arenson, L Aschenbrenner, ...
Nature communications 12 (1), 6055, 2021
1962021
Identification of the functional core of the influenza A virus A/M2 proton-selective ion channel
C Ma, AL Polishchuk, Y Ohigashi, AL Stouffer, A Schön, E Magavern, ...
Proceedings of the National Academy of Sciences 106 (30), 12283-12288, 2009
1842009
Molecular dynamics simulation directed rational design of inhibitors targeting drug-resistant mutants of influenza A virus M2
J Wang, C Ma, G Fiorin, V Carnevale, T Wang, F Hu, RA Lamb, LH Pinto, ...
Journal of the American Chemical Society 133 (32), 12834-12841, 2011
1622011
Discovery of SARS-CoV-2 papain-like protease inhibitors through a combination of high-throughput screening and a FlipGFP-based reporter assay
C Ma, MD Sacco, Z Xia, G Lambrinidis, JA Townsend, Y Hu, X Meng, ...
ACS central science 7 (7), 1245-1260, 2021
1202021
Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus
J Wang, C Ma, J Wang, H Jo, B Canturk, G Fiorin, LH Pinto, RA Lamb, ...
Journal of medicinal chemistry 56 (7), 2804-2812, 2013
1172013
Expedited approach toward the rational design of noncovalent SARS-CoV-2 main protease inhibitors
N Kitamura, MD Sacco, C Ma, Y Hu, JA Townsend, X Meng, F Zhang, ...
Journal of medicinal chemistry 65 (4), 2848-2865, 2021
1142021
Discovery of a novel inhibitor of coronavirus 3CL protease for the potential treatment of COVID-19
B Boras, RM Jones, BJ Anson, D Arenson, L Aschenbrenner, ...
BioRxiv, 2020.09. 12.293498, 2020
1102020
Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 …
Y Wu, B Canturk, H Jo, C Ma, E Gianti, ML Klein, LH Pinto, RA Lamb, ...
Journal of the American Chemical Society 136 (52), 17987-17995, 2014
962014
Discovery of di-and trihaloacetamides as covalent SARS-CoV-2 main protease inhibitors with high target specificity
C Ma, Z Xia, MD Sacco, Y Hu, JA Townsend, X Meng, J Choza, H Tan, ...
Journal of the American Chemical Society 143 (49), 20697-20709, 2021
952021
The amphipathic helix of influenza A virus M2 protein is required for filamentous bud formation and scission of filamentous and spherical particles
KL Roberts, GP Leser, C Ma, RA Lamb
Journal of virology 87 (18), 9973-9982, 2013
912013
Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus
MD Duque, C Ma, E Torres, J Wang, L Naesens, J Juárez-Jiménez, ...
Journal of medicinal chemistry 54 (8), 2646-2657, 2011
882011
pH-induced conformational change of the influenza M2 protein C-terminal domain
PA Nguyen, CS Soto, A Polishchuk, GA Caputo, CD Tatko, C Ma, ...
Biochemistry 47 (38), 9934-9936, 2008
842008
Boceprevir, calpain inhibitors II and XII, and GC-376 have broad-spectrum antiviral activity against coronaviruses
Y Hu, C Ma, T Szeto, B Hurst, B Tarbet, J Wang
ACS infectious diseases 7 (3), 586-597, 2021
772021
Rational design of hybrid SARS-CoV-2 main protease inhibitors guided by the superimposed cocrystal structures with the peptidomimetic inhibitors GC-376, telaprevir, and boceprevir
Z Xia, M Sacco, Y Hu, C Ma, X Meng, F Zhang, T Szeto, Y Xiang, Y Chen, ...
ACS Pharmacology & Translational Science 4 (4), 1408-1421, 2021
762021
Exploring organosilane amines as potent inhibitors and structural probes of influenza a virus M2 proton channel
J Wang, C Ma, Y Wu, RA Lamb, LH Pinto, WF DeGrado
Journal of the American Chemical Society 133 (35), 13844-13847, 2011
742011
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Articles 1–20