|Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018|
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
|p53-and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa|
A Villunger, EM Michalak, L Coultas, F Müllauer, G Böck, ...
Science 302 (5647), 1036-1038, 2003
|Essential versus accessory aspects of cell death: recommendations of the NCCD 2015|
L Galluzzi, JM Bravo-San Pedro, I Vitale, SA Aaronson, JM Abrams, ...
Cell Death & Differentiation 22 (1), 58-73, 2015
|Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis|
H Puthalakath, A Villunger, LA O'Reilly, JG Beaumont, L Coultas, ...
Science 293 (5536), 1829-1832, 2001
|LDHA-associated lactic acid production blunts tumor immunosurveillance by T and NK cells|
A Brand, K Singer, GE Koehl, M Kolitzus, G Schoenhammer, A Thiel, ...
Cell metabolism 24 (5), 657-671, 2016
|FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal|
H You, M Pellegrini, K Tsuchihara, K Yamamoto, G Hacker, M Erlacher, ...
The Journal of experimental medicine 203 (7), 1657-1663, 2006
|Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic|
J Kuroda, H Puthalakath, MS Cragg, PN Kelly, P Bouillet, DCS Huang, ...
Proceedings of the National Academy of Sciences 103 (40), 14907-14912, 2006
|Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-xL|
DCS Huang, M Hahne, M Schroeter, K Frei, A Fontana, A Villunger, ...
Proceedings of the National Academy of Sciences 96 (26), 14871-14876, 1999
|Bcl2 family proteins in carcinogenesis and the treatment of cancer|
A Frenzel, F Grespi, W Chmelewskij, A Villunger
Apoptosis 14 (4), 584-596, 2009
|BH3-only proteins Puma and Bim are rate-limiting for γ-radiation–and glucocorticoid-induced apoptosis of lymphoid cells in vivo|
M Erlacher, EM Michalak, PN Kelly, V Labi, H Niederegger, L Coultas, ...
Blood 106 (13), 4131-4138, 2005
|Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy|
TT Tan, K Degenhardt, DA Nelson, B Beaudoin, W Nieves-Neira, ...
Cancer cell 7 (3), 227-238, 2005
|Noxa: at the tip of the balance between life and death|
C Ploner, R Kofler, A Villunger
Oncogene 27 (1), S84-S92, 2008
|Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci|
E Melum, A Franke, C Schramm, TJ Weismüller, DN Gotthardt, FA Offner, ...
Nature genetics 43 (1), 17-19, 2011
|Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction|
M Erlacher, V Labi, C Manzl, G Böck, A Tzankov, G Häcker, E Michalak, ...
The Journal of experimental medicine 203 (13), 2939-2951, 2006
|p14–MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis|
D Teis, N Taub, R Kurzbauer, D Hilber, ME de Araujo, M Erlacher, ...
The Journal of cell biology 175 (6), 861-868, 2006
|How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression?|
A Olsson, C Manzl, A Strasser, A Villunger
Cell Death & Differentiation 14 (9), 1561-1575, 2007
|In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute|
EM Michalak, A Villunger, JM Adams, A Strasser
Cell Death & Differentiation 15 (6), 1019-1029, 2008
|Drug-induced apoptosis is associated with enhanced Fas (Apo-1/CD95) ligand expression but occurs independently of Fas (Apo-1/CD95) signaling in human T-acute lymphatic leukemia …|
A Villunger, A Egle, M Kos, BL Hartmann, S Geley, R Kofler, R Greil
Cancer Research 57 (16), 3331-3334, 1997
|BH3-only proteins in cell death initiation, malignant disease and anticancer therapy|
V Labi, M Erlacher, S Kiessling, A Villunger
Cell Death & Differentiation 13 (8), 1325-1338, 2006
|Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: a breakthrough in anticancer therapy?|
V Labi, F Grespi, F Baumgartner, A Villunger
Cell Death & Differentiation 15 (6), 977-987, 2008