Structure of the human κ-opioid receptor in complex with JDTic H Wu, D Wacker, M Mileni, V Katritch, GW Han, E Vardy, W Liu, ... Nature 485 (7398), 327-332, 2012 | 902 | 2012 |
Structural features for functional selectivity at serotonin receptors D Wacker, C Wang, V Katritch, GW Han, XP Huang, E Vardy, JD McCorvy, ... Science 340 (6132), 615-619, 2013 | 592 | 2013 |
Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography U Weierstall, D James, C Wang, TA White, D Wang, W Liu, JCH Spence, ... Nature communications 5 (1), 1-6, 2014 | 460 | 2014 |
Structural basis for molecular recognition at serotonin receptors C Wang, Y Jiang, J Ma, H Wu, D Wacker, V Katritch, GW Han, W Liu, ... Science 340 (6132), 610-614, 2013 | 446 | 2013 |
Serial femtosecond crystallography of G protein–coupled receptors W Liu, D Wacker, C Gati, GW Han, D James, D Wang, G Nelson, ... Science 342 (6165), 1521-1524, 2013 | 433 | 2013 |
Structure of the human glucagon class B G-protein-coupled receptor FY Siu, M He, C De Graaf, GW Han, D Yang, Z Zhang, C Zhou, Q Xu, ... Nature 499 (7459), 444-449, 2013 | 391 | 2013 |
Conserved Binding Mode of Human β2 Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography D Wacker, G Fenalti, MA Brown, V Katritch, R Abagyan, V Cherezov, ... Journal of the American Chemical Society 132 (33), 11443-11445, 2010 | 356 | 2010 |
How ligands illuminate GPCR molecular pharmacology D Wacker, RC Stevens, BL Roth Cell 170 (3), 414-427, 2017 | 265 | 2017 |
Crystal structure of an LSD-bound human serotonin receptor D Wacker, S Wang, JD McCorvy, RM Betz, AJ Venkatakrishnan, A Levit, ... Cell 168 (3), 377-389. e12, 2017 | 221 | 2017 |
Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone S Wang, T Che, A Levit, BK Shoichet, D Wacker, BL Roth Nature 555 (7695), 269-273, 2018 | 196 | 2018 |
Structure of the nanobody-stabilized active state of the kappa opioid receptor T Che, S Majumdar, SA Zaidi, P Ondachi, JD McCorvy, S Wang, ... Cell 172 (1-2), 55-67. e15, 2018 | 178 | 2018 |
D4 dopamine receptor high-resolution structures enable the discovery of selective agonists S Wang, D Wacker, A Levit, T Che, RM Betz, JD McCorvy, ... Science 358 (6361), 381-386, 2017 | 120 | 2017 |
5-HT2C receptor structures reveal the structural basis of GPCR polypharmacology Y Peng, JD McCorvy, K Harpsøe, K Lansu, S Yuan, P Popov, L Qu, M Pu, ... Cell 172 (4), 719-730. e14, 2018 | 108 | 2018 |
GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles AA Thompson, JJ Liu, E Chun, D Wacker, H Wu, V Cherezov, RC Stevens Methods 55 (4), 310-317, 2011 | 84 | 2011 |
Structural and functional analysis of Nup120 suggests ring formation of the Nup84 complex HS Seo, Y Ma, EW Debler, D Wacker, S Kutik, G Blobel, A Hoelz Proceedings of the National Academy of Sciences 106 (34), 14281-14286, 2009 | 79 | 2009 |
Agonists for 13 trace amine-associated receptors provide insight into the molecular basis of odor selectivity DM Ferrero, D Wacker, MA Roque, MW Baldwin, RC Stevens, SD Liberles ACS chemical biology 7 (7), 1184-1189, 2012 | 65 | 2012 |
Structural determinants of 5-HT 2B receptor activation and biased agonism JD McCorvy, D Wacker, S Wang, B Agegnehu, J Liu, K Lansu, AR Tribo, ... Nature structural & molecular biology 25 (9), 787-796, 2018 | 52 | 2018 |
Femtosecond crystallography of membrane proteins in the lipidic cubic phase W Liu, D Wacker, C Wang, E Abola, V Cherezov Philosophical Transactions of the Royal Society B: Biological Sciences 369 …, 2014 | 51 | 2014 |
Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody A Ishchenko, D Wacker, M Kapoor, A Zhang, GW Han, S Basu, N Patel, ... Proceedings of the National Academy of Sciences 114 (31), 8223-8228, 2017 | 37 | 2017 |
Structure of a hallucinogen-activated gq-coupled 5-ht2a serotonin receptor K Kim, T Che, O Panova, JF DiBerto, J Lyu, BE Krumm, D Wacker, ... Cell 182 (6), 1574-1588. e19, 2020 | 25 | 2020 |