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Lukas Chavez
Lukas Chavez
Assistant Professor, Department of Medicine, University of California, San Diego (UCSD)
Adresse e-mail validée de ucsd.edu - Page d'accueil
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Année
DNA methylation-based classification of central nervous system tumours
D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ...
Nature 555 (7697), 469-474, 2018
21882018
The landscape of genomic alterations across childhood cancers
SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ...
Nature 555 (7696), 321-327, 2018
12592018
The whole-genome landscape of medulloblastoma subtypes
PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ...
Nature 547 (7663), 311-317, 2017
9402017
DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis
F Sahm, D Schrimpf, D Stichel, DTW Jones, T Hielscher, S Schefzyk, ...
The lancet oncology 18 (5), 682-694, 2017
6972017
Atypical teratoid/rhabdoid tumors are comprised of three epigenetic subgroups with distinct enhancer landscapes
PD Johann, S Erkek, M Zapatka, K Kerl, I Buchhalter, V Hovestadt, ...
Cancer cell 29 (3), 379-393, 2016
5202016
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX
M Ko, J An, HS Bandukwala, L Chavez, T Äijö, WA Pastor, MF Segal, H Li, ...
Nature 497 (7447), 122-126, 2013
4352013
Active medulloblastoma enhancers reveal subgroup-specific cellular origins
CY Lin, S Erkek, Y Tong, L Yin, AJ Federation, M Zapatka, P Haldipur, ...
Nature 530 (7588), 57-62, 2016
3902016
PET-guided treatment in patients with advanced-stage Hodgkin's lymphoma (HD18): final results of an open-label, international, randomised phase 3 trial by the German Hodgkin …
P Borchmann, H Goergen, C Kobe, A Lohri, R Greil, DA Eichenauer, ...
The Lancet 390 (10114), 2790-2802, 2017
3582017
Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort
SM Waszak, PA Northcott, I Buchhalter, GW Robinson, C Sutter, ...
The Lancet Oncology 19 (6), 785-798, 2018
3482018
MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments
M Lienhard, C Grimm, M Morkel, R Herwig, L Chavez
Bioinformatics 30 (2), 284-286, 2014
3222014
Large conserved domains of low DNA methylation maintained by Dnmt3a
M Jeong, D Sun, M Luo, Y Huang, GA Challen, B Rodriguez, X Zhang, ...
Nature genetics 46 (1), 17-23, 2014
3172014
Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells
Y Huang, L Chavez, X Chang, X Wang, WA Pastor, J Kang, ...
Proceedings of the National Academy of Sciences 111 (4), 1361-1366, 2014
2932014
Innate-like functions of natural killer T cell subsets result from highly divergent gene programs
I Engel, G Seumois, L Chavez, D Samaniego-Castruita, B White, ...
Nature immunology 17 (6), 728-739, 2016
2852016
Dynamic changes in chromatin accessibility occur in CD8+ T cells responding to viral infection
JP Scott-Browne, IF López-Moyado, S Trifari, V Wong, L Chavez, A Rao, ...
Immunity 45 (6), 1327-1340, 2016
2742016
Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes
T Sharma, EC Schwalbe, D Williamson, M Sill, V Hovestadt, M Mynarek, ...
Acta neuropathologica 138, 309-326, 2019
2272019
Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas
KW Pajtler, J Wen, M Sill, T Lin, W Orisme, B Tang, JM Hübner, ...
Acta neuropathologica 136, 211-226, 2018
2262018
Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic …
JT Huse, M Snuderl, DTW Jones, CD Brathwaite, N Altman, E Lavi, ...
Acta neuropathologica 133, 417-429, 2017
2052017
Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility
G Seumois, L Chavez, A Gerasimova, M Lienhard, N Omran, L Kalinke, ...
Nature immunology 15 (8), 777-788, 2014
2012014
Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome
P Panwalkar, J Clark, V Ramaswamy, D Hawes, F Yang, C Dunham, ...
Acta neuropathologica 134, 705-714, 2017
1962017
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling
SC Mack, KW Pajtler, L Chavez, K Okonechnikov, KC Bertrand, X Wang, ...
Nature 553 (7686), 101-105, 2018
1952018
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