| Flavoprotein disulfide reductases: advances in chemistry and function. A Argyrou, JS Blanchard Progress in nucleic acid research and molecular biology 78, 89-142, 2004 | 241 | 2004 |
| Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid A Argyrou, MW Vetting, B Aladegbami, JS Blanchard Nature structural & molecular biology 13 (5), 408-413, 2006 | 183 | 2006 |
| EED-targeted PROTACs degrade EED, EZH2, and SUZ12 in the PRC2 complex JHR Hsu, T Rasmusson, J Robinson, F Pachl, J Read, S Kawatkar, ... Cell chemical biology 27 (1), 41-46. e17, 2020 | 163 | 2020 |
| Proteome-wide Profiling of Isoniazid Targets in Mycobacterium tuberculosis A Argyrou, L Jin, L Siconilfi-Baez, RH Angeletti, JS Blanchard Biochemistry 45 (47), 13947-13953, 2006 | 116 | 2006 |
| Enabling lead discovery for histone lysine demethylases by high-throughput RapidFire mass spectrometry SE Hutchinson, MV Leveridge, ML Heathcote, P Francis, L Williams, ... Journal of biomolecular screening 17 (1), 39-48, 2012 | 112 | 2012 |
| N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis T Warrier, K Kapilashrami, A Argyrou, TR Ioerger, D Little, KC Murphy, ... Proceedings of the National Academy of Sciences 113 (31), E4523-E4530, 2016 | 108 | 2016 |
| Kinetic and Chemical Mechanism of Mycobacterium tuberculosis 1-Deoxy-d-xylulose-5-phosphate Isomeroreductase A Argyrou, JS Blanchard Biochemistry 43 (14), 4375-4384, 2004 | 103 | 2004 |
| Identification of KasA as the cellular target of an anti-tubercular scaffold KA Abrahams, C Chung, S Ghidelli-Disse, J Rullas, MJ Rebollo-López, ... Nature communications 7 (1), 12581, 2016 | 91 | 2016 |
| Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase SM Batt, M Cacho Izquierdo, J Castro Pichel, CJ Stubbs, ... ACS Infectious Diseases 1 (12), 615-626, 2015 | 65 | 2015 |
| Mycobacterium tuberculosis Lipoamide Dehydrogenase Is Encoded by Rv0462 and Not by the lpdA or lpdB Genes A Argyrou, JS Blanchard Biochemistry 40 (38), 11353-11363, 2001 | 57 | 2001 |
| New Insight into the Mechanism of Action of and Resistance to Isoniazid: Interaction of Mycobacterium tuberculosis enoyl-ACP Reductase with INH-NADP A Argyrou, MW Vetting, JS Blanchard Journal of the American Chemical Society 129 (31), 9582-9583, 2007 | 55 | 2007 |
| Insight into the therapeutic selectivity of the irreversible EGFR tyrosine kinase inhibitor osimertinib through enzyme kinetic studies X Zhai, RA Ward, P Doig, A Argyrou Biochemistry 59 (14), 1428-1441, 2020 | 50 | 2020 |
| Demonstrating enhanced throughput of RapidFire mass spectrometry through multiplexing using the JmjD2d demethylase as a model system M Leveridge, R Buxton, A Argyrou, P Francis, B Leavens, A West, M Rees, ... Journal of Biomolecular Screening 19 (2), 278-286, 2014 | 50 | 2014 |
| Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1 A Richter, I Rudolph, U Möllmann, K Voigt, C Chung, OMP Singh, M Rees, ... Scientific reports 8 (1), 13473, 2018 | 49 | 2018 |
| Slow-onset Feedback Inhibition: Inhibition of Mycobacterium tuberculosis α-Isopropylmalate Synthase by l-Leucine LPS De Carvalho, A Argyrou, JS Blanchard Journal of the American Chemical Society 127 (28), 10004-10005, 2005 | 47 | 2005 |
| Lead discovery for human kynurenine 3-monooxygenase by high-throughput RapidFire mass spectrometry DM Lowe, M Gee, C Haslam, B Leavens, E Christodoulou, P Hissey, ... Journal of biomolecular screening 19 (4), 508-515, 2014 | 43 | 2014 |
| Catalysis of Diaphorase Reactions by Mycobacterium tuberculosis Lipoamide Dehydrogenase Occurs at the EH4 Level A Argyrou, G Sun, BA Palfey, JS Blanchard Biochemistry 42 (7), 2218-2228, 2003 | 43 | 2003 |
| Dihydroorotate Dehydrogenase from Clostridium oroticum Is a Class 1B Enzyme and Utilizes a Concerted Mechansim of Catalysis A Argyrou, MW Washabaugh, CM Pickart Biochemistry 39 (34), 10373-10384, 2000 | 43 | 2000 |
| Identification and profiling of hydantoins—A novel class of potent antimycobacterial DprE1 inhibitors MK Rogacki, E Pitta, O Balabon, S Huss, EM Lopez-Roman, A Argyrou, ... Journal of Medicinal Chemistry 61 (24), 11221-11249, 2018 | 38 | 2018 |
| The Lipoamide Dehydrogenase from Mycobacterium tuberculosis Permits the Direct Observation of Flavin Intermediates in Catalysis A Argyrou, JS Blanchard, BA Palfey Biochemistry 41 (49), 14580-14590, 2002 | 29 | 2002 |
