| Discovery of reactive microbiota-derived metabolites that inhibit host proteases CJ Guo, FY Chang, TP Wyche, KM Backus, TM Acker, M Funabashi, ... Cell 168 (3), 517-526. e18, 2017 | 214 | 2017 |
| Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators TM Acker, H Yuan, KB Hansen, KM Vance, KK Ogden, HS Jensen, ... Molecular pharmacology 80 (5), 782-795, 2011 | 117 | 2011 |
| Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-Selective N-Methyl-d-aspartate Receptor Antagonists CA Mosley, TM Acker, KB Hansen, P Mullasseril, KT Andersen, P Le, ... Journal of medicinal chemistry 53 (15), 5476-5490, 2010 | 110 | 2010 |
| Novel NMDA receptor modulators: an update RM Santangelo, TM Acker, SS Zimmerman, BM Katzman, KL Strong, ... Expert opinion on therapeutic patents 22 (11), 1337-1352, 2012 | 90 | 2012 |
| The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor–induced apoptosis SM Raja, S Chen, P Yue, TM Acker, B Lefkove, JL Arbiser, FR Khuri, ... Molecular cancer therapeutics 7 (7), 2212-2223, 2008 | 62 | 2008 |
| The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor–induced apoptosis SM Raja, S Chen, P Yue, TM Acker, B Lefkove, JL Arbiser, FR Khuri, ... Molecular cancer therapeutics 7 (7), 2212-2223, 2008 | 62 | 2008 |
| Structure–activity relationships and pharmacophore model of a noncompetitive pyrazoline containing class of GluN2C/GluN2D selective antagonists TM Acker, A Khatri, KM Vance, C Slabber, J Bacsa, JP Snyder, ... Journal of medicinal chemistry 56 (16), 6434-6456, 2013 | 59 | 2013 |
| A novel negative allosteric modulator selective for GluN2C/2D-containing NMDA receptors inhibits synaptic transmission in hippocampal interneurons SA Swanger, KM Vance, TM Acker, SS Zimmerman, JO DiRaddo, ... ACS chemical neuroscience 9 (2), 306-319, 2018 | 53 | 2018 |
| Current and potential treatments for ubiquitous but neglected herpesvirus infections JE Gable, TM Acker, CS Craik Chemical Reviews 114 (22), 11382-11412, 2014 | 30 | 2014 |
| Allosteric inhibitors, crystallography, and comparative analysis reveal network of coordinated movement across human herpesvirus proteases TM Acker, JE Gable, MF Bohn, P Jaishankar, MC Thompson, JS Fraser, ... Journal of the American Chemical Society 139 (34), 11650-11653, 2017 | 18 | 2017 |
| Fragment‐Based Protein–Protein Interaction Antagonists of a Viral Dimeric Protease JE Gable, GM Lee, TM Acker, KR Hulce, ER Gonzalez, P Schweigler, ... ChemMedChem 11 (8), 862-869, 2016 | 12 | 2016 |
| Triflic anhydride promoted intramolecular cyclization of N-aryl cinnamides: access to polysubstituted quinolin-2 (1H)-ones Q Zhang, J Yuan, M Yu, R Zhang, Y Liang, P Huang, D Dong Synthesis 49 (22), 4996-5002, 2017 | 9 | 2017 |
| Subunit selective nmda receptor antagonists for the treatment of neurological conditions SF Traynelis, DC Liotta, C Mosley, TM Acker, S Shelley | 3 | 2010 |
| Constructs specifically recognizing glypican 3 and uses thereof P Zhang, Y Xu, J Morales, Y Nakano, H Liu, J Xiang, T Acker US Patent App. 17/817,308, 2023 | 1 | 2023 |
| Constructs specifically recognizing glypican 3 and uses thereof P Zhang, Y Xu, J Morales, Y Nakano, H Liu, J Xiang, T Acker US Patent 11,447,564, 2022 | 1 | 2022 |
| Pyrazoline dihydroquinolones, pharmaceutical compositions, and uses TM Acker, DC Liotta, SF Traynelis, Y Jing US Patent 11,117,882, 2021 | 1 | 2021 |
| Pyrazoline Dihydroquinolones, Pharmaceutical Compositions, and Uses TM Acker, DC Liotta, SF Traynelis US Patent App. 14/901,628, 2016 | 1 | 2016 |
| Development of a Dihydroquinoline–Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor MP D’Erasmo, NS Akins, P Ma, Y Jing, SA Swanger, SK Sharma, ... ACS Chemical Neuroscience 14 (17), 3059-3076, 2023 | | 2023 |
| Pyrazoline Dihydroquinolones, Pharmaceutical Compositions, and Uses TM Acker, DC Liotta, SF Traynelis, Y Jing US Patent App. 17/404,579, 2021 | | 2021 |
| CONSTRUCTIONS SPECIFICALLY RECOGNIZING GLYPICANE 3 AND USES OF SUCH LATEST P Zhang, XU Yiyang, J Morales, Y Nakano, H Liu, J Xiang, T ACKER | | 2021 |
