The single-cell transcriptional landscape of mammalian organogenesis J Cao, M Spielmann, X Qiu, X Huang, DM Ibrahim, AJ Hill, F Zhang, ... Nature 566 (7745), 496-502, 2019 | 2940 | 2019 |
Formation of new chromatin domains determines pathogenicity of genomic duplications M Franke, DM Ibrahim, G Andrey, W Schwarzer, V Heinrich, R Schöpflin, ... Nature 538 (7624), 265-269, 2016 | 713 | 2016 |
Functional dissection of the Sox9–Kcnj2 locus identifies nonessential and instructive roles of TAD architecture A Despang, R Schöpflin, M Franke, S Ali, I Jerković, C Paliou, WL Chan, ... Nature genetics 51 (8), 1263-1271, 2019 | 303 | 2019 |
Deletions, inversions, duplications: engineering of structural variants using CRISPR/Cas in mice K Kraft, S Geuer, AJ Will, WL Chan, C Paliou, M Borschiwer, I Harabula, ... Cell reports 10 (5), 833-839, 2015 | 252 | 2015 |
Unblending of transcriptional condensates in human repeat expansion disease S Basu, SD Mackowiak, H Niskanen, D Knezevic, V Asimi, S Grosswendt, ... Cell 181 (5), 1062-1079. e30, 2020 | 155 | 2020 |
Characterization of hundreds of regulatory landscapes in developing limbs reveals two regimes of chromatin folding G Andrey, R Schöpflin, I Jerković, V Heinrich, DM Ibrahim, C Paliou, ... Genome research 27 (2), 223-233, 2017 | 144 | 2017 |
Homeotic arm-to-leg transformation associated with genomic rearrangements at the PITX1 locus M Spielmann, F Brancati, PM Krawitz, PN Robinson, DM Ibrahim, ... The American Journal of Human Genetics 91 (4), 629-635, 2012 | 140 | 2012 |
Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformations K Kraft, A Magg, V Heinrich, C Riemenschneider, R Schöpflin, ... Nature cell biology 21 (3), 305-310, 2019 | 132 | 2019 |
Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development P Vallecillo-García, M Orgeur, S vom Hofe-Schneider, J Stumm, V Kappert, ... Nature Communications 8 (1), 1218, 2017 | 112 | 2017 |
Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A P Kuss, K Kraft, J Stumm, D Ibrahim, P Vallecillo-Garcia, S Mundlos, ... Developmental biology 385 (1), 83-93, 2014 | 88 | 2014 |
The role of 3D chromatin domains in gene regulation: a multi-facetted view on genome organization DM Ibrahim, S Mundlos Current opinion in genetics & development 61, 1-8, 2020 | 71 | 2020 |
Three-dimensional chromatin in disease: what holds us together and what drives us apart? DM Ibrahim, S Mundlos Current Opinion in Cell Biology 64, 1-9, 2020 | 70 | 2020 |
Genome-wide binding of posterior HOXA/D transcription factors reveals subgrouping and association with CTCF I Jerković, DM Ibrahim, G Andrey, S Haas, P Hansen, C Janetzki, ... PLoS genetics 13 (1), e1006567, 2017 | 54 | 2017 |
Distinct global shifts in genomic binding profiles of limb malformation-associated HOXD13 mutations DM Ibrahim, P Hansen, C Rödelsperger, AC Stiege, SC Doelken, D Horn, ... Genome research 23 (12), 2091-2102, 2013 | 40 | 2013 |
Mutation in LBX1/Lbx1 precludes transcription factor cooperativity and causes congenital hypoventilation in humans and mice LR Hernandez-Miranda, DM Ibrahim, PL Ruffault, M Larrosa, K Balueva, ... Proceedings of the National Academy of Sciences 115 (51), 13021-13026, 2018 | 37 | 2018 |
Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes AR Ringel, Q Szabo, AM Chiariello, K Chudzik, R Schöpflin, P Rothe, ... Cell 185 (20), 3689-3704. e21, 2022 | 35 | 2022 |
Saturation analysis of ChIP-seq data for reproducible identification of binding peaks P Hansen, J Hecht, DM Ibrahim, A Krannich, M Truss, PN Robinson Genome research 25 (9), 1391-1400, 2015 | 34 | 2015 |
Microarray Comparison of Anterior and Posterior Drosophila Wing Imaginal Disc Cells Identifies Novel Wing Genes DM Ibrahim, B Biehs, TB Kornberg, A Klebes G3: Genes, Genomes, Genetics 3 (8), 1353-1362, 2013 | 24 | 2013 |
A homozygous HOXD13 missense mutation causes a severe form of synpolydactyly with metacarpal to carpal transformation DM Ibrahim, N Tayebi, A Knaus, AC Stiege, A Sahebzamani, J Hecht, ... American journal of medical genetics Part A 170 (3), 615-621, 2016 | 22 | 2016 |
Single-cell, whole-embryo phenotyping of mammalian developmental disorders X Huang, J Henck, C Qiu, VKA Sreenivasan, S Balachandran, OV Amarie, ... Nature 623 (7988), 772-781, 2023 | 8 | 2023 |