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G. Paul Savage
G. Paul Savage
Verified email at csiro.au
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Cubane: 50 years later
KF Biegasiewicz, JR Griffiths, GP Savage, J Tsanaktsidis, R Priefer
Chemical reviews 115 (14), 6719-6745, 2015
1772015
Validating Eaton's hypothesis: Cubane as a benzene bioisostere
BA Chalmers, H Xing, S Houston, C Clark, S Ghassabian, A Kuo, B Cao, ...
Angewandte Chemie International Edition 55 (11), 3580-3585, 2016
1512016
Cycloaddition reactions of nitrile oxides with alkenes
CJ Easton, CMM Hughes, GP Savage, GW Simpson
Advances in Heterocyclic Chemistry 60, 261-327, 1994
961994
Total synthesis of the potent anticancer Aglaia metabolites (−)-silvestrol and (−)-episilvestrol and the active analogue (−)-4′-desmethoxyepisilvestrol
TE Adams, M El Sous, BC Hawkins, S Hirner, G Holloway, ML Khoo, ...
Journal of the American Chemical Society 131 (4), 1607-1616, 2009
882009
A Concise Route to Dihydrobenzo[b]furans: Formal Total Synthesis of (+)-Lithospermic Acid
J Fischer, GP Savage, MJ Coster
Organic Letters 13 (13), 3376-3379, 2011
802011
Nonclassical phenyl bioisosteres as effective replacements in a series of novel open-source antimalarials
EG Tse, SD Houston, CM Williams, GP Savage, LM Rendina, ...
Journal of Medicinal Chemistry 63 (20), 11585-11601, 2020
752020
Methyllycaconitine analogues have mixed antagonist effects at nicotinic acetylcholine receptors
D Barker, DHS Lin, JE Carland, CPY Chu, M Chebib, MA Brimble, ...
Bioorganic & medicinal chemistry 13 (14), 4565-4575, 2005
712005
Synthesis of biotinylated episilvestrol: highly selective targeting of the translation factors eIF4AI/II
JM Chambers, LM Lindqvist, A Webb, DCS Huang, GP Savage, ...
Organic letters 15 (6), 1406-1409, 2013
692013
The direct α-C (sp 3)–H functionalisation of N-aryl tetrahydroisoquinolines via an iron-catalysed aerobic nitro-Mannich reaction and continuous flow processing
M Brzozowski, JA Forni, GP Savage, A Polyzos
Chemical communications 51 (2), 334-337, 2015
682015
Evolution of abiotic cubane chemistries in a nucleic acid aptamer allows selective recognition of a malaria biomarker
YW Cheung, P Röthlisberger, AE Mechaly, P Weber, F Levi-Acobas, Y Lo, ...
Proceedings of the National Academy of Sciences 117 (29), 16790-16798, 2020
662020
Reducing the cost, smell, and toxicity of the Barton reductive decarboxylation: Chloroform as the hydrogen atom source
EJ Ko, GP Savage, CM Williams, J Tsanaktsidis
Organic Letters 13 (8), 1944-1947, 2011
632011
The cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complement
SD Houston, T Fahrenhorst-Jones, H Xing, BA Chalmers, ML Sykes, ...
Organic & Biomolecular Chemistry 17 (28), 6790-6798, 2019
612019
Small molecule inhibitors of the LEDGF site of human immunodeficiency virus integrase identified by fragment screening and structure based design
TS Peat, DI Rhodes, N Vandegraaff, G Le, JA Smith, LJ Clark, ED Jones, ...
PloS one 7 (7), e40147, 2012
612012
Pilot-scale production of dimethyl 1, 4-cubanedicarboxylate
MJ Falkiner, SW Littler, KJ McRae, GP Savage, J Tsanaktsidis
Organic Process Research & Development 17 (12), 1503-1509, 2013
602013
Structural Basis for a New Mechanism of Inhibition of HI V-1 Integrase Identified by Fragment Screening and Structure-Based Design
DI Rhodes, TS Peat, N Vandegraaff, D Jeevarajah, G Le, ED Jones, ...
Antiviral Chemistry and Chemotherapy 21 (4), 155-168, 2011
572011
Spiro isoxazolines via nitrile oxide 1, 3-dipolar cycloaddition reactions
GP Savage
Curr. Org. Chem 14, 1478-1499, 2010
562010
Reversal of regiochemistry in the synthesis of isoxazoles by nitrile oxide cycloadditions
CJ Easton, CM Hughes, ERT Tiekink, CE Lubin, GP Savage, ...
Tetrahedron letters 35 (21), 3589-3592, 1994
481994
Chloroform as a hydrogen atom donor in Barton reductive decarboxylation reactions
J Ho, J Zheng, R Meana-Pañeda, DG Truhlar, EJ Ko, GP Savage, ...
The Journal of Organic Chemistry 78 (13), 6677-6687, 2013
452013
The cyclic structure of 2-iodosyl-and 2-iodyl-benzoic acid anions: a basicity and X-ray crystallographic study
G PauláSavage, H DupontáDurst
Journal of the Chemical Society, Perkin Transactions 2, 1657-1661, 1990
411990
An enantioselective total synthesis of the stilbenolignan (−)-aiphanol and the determination of its absolute stereochemistry
MG Banwell, S Chand, GP Savage
Tetrahedron: Asymmetry 16 (9), 1645-1654, 2005
392005
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