Yun Chen
Yun Chen
Department of Biology and Biological Engineering, Chalmers University of Technology
Verified email at
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Altered sterol composition renders yeast thermotolerant
L Caspeta, Y Chen, P Ghiaci, A Feizi, S Buskov, BM Hallström, ...
Science 346 (6205), 75-78, 2014
Establishing a platform cell factory through engineering of yeast acetyl-CoA metabolism
Y Chen, L Daviet, M Schalk, V Siewers, J Nielsen
Metabolic engineering 15, 48-54, 2013
Microbial acetyl-CoA metabolism and metabolic engineering
A Krivoruchko, Y Zhang, V Siewers, Y Chen, J Nielsen
Metabolic engineering 28, 28-42, 2015
Dynamic control of gene expression in Saccharomyces cerevisiae engineered for the production of plant sesquitepene α-santalene in a fed-batch mode
G Scalcinati, C Knuf, S Partow, Y Chen, J Maury, M Schalk, L Daviet, ...
Metabolic engineering 14 (2), 91-103, 2012
De novo production of resveratrol from glucose or ethanol by engineered Saccharomyces cerevisiae
M Li, KR Kildegaard, Y Chen, A Rodriguez, I Borodina, J Nielsen
Metabolic Engineering 32, 1-11, 2015
Diversion of Flux toward Sesquiterpene Production in Saccharomyces cerevisiae by Fusion of Host and Heterologous Enzymes
L Albertsen, Y Chen, LS Bach, S Rattleff, J Maury, S Brix, J Nielsen, ...
Applied and Environmental Microbiology 77 (3), 1033-1040, 2011
Improving production of malonyl coenzyme A-derived metabolites by abolishing Snf1-dependent regulation of Acc1
S Shi, Y Chen, V Siewers, J Nielsen
MBio 5 (3), e01130-14, 2014
Advances in metabolic pathway and strain engineering paving the way for sustainable production of chemical building blocks
Y Chen, J Nielsen
Current opinion in biotechnology 24 (6), 965-972, 2013
Biobased organic acids production by metabolically engineered microorganisms
Y Chen, J Nielsen
Current opinion in biotechnology 37, 165-172, 2016
Profiling of cytosolic and peroxisomal acetyl-CoA metabolism in Saccharomyces cerevisiae
Y Chen, V Siewers, J Nielsen
PloS one 7 (8), e42475, 2012
Coupled incremental precursor and co-factor supply improves 3-hydroxypropionic acid production in Saccharomyces cerevisiae
Y Chen, J Bao, IK Kim, V Siewers, J Nielsen
Metabolic engineering 22, 104-109, 2014
Improving biobutanol production in engineered Saccharomyces cerevisiae by manipulation of acetyl-CoA metabolism
A Krivoruchko, C Serrano-Amatriain, Y Chen, V Siewers, J Nielsen
Journal of Industrial Microbiology and Biotechnology 40 (9), 1051-1056, 2013
Lipid engineering combined with systematic metabolic engineering of Saccharomyces cerevisiae for high-yield production of lycopene
T Ma, B Shi, Z Ye, X Li, M Liu, Y Chen, J Xia, J Nielsen, Z Deng, T Liu
Metabolic engineering 52, 134-142, 2019
Genetic modulation of the overexpression of tailoring genes eryK and eryG leading to the improvement of erythromycin A purity and production in Saccharopolyspora erythraea …
Y Chen, W Deng, J Wu, J Qian, J Chu, Y Zhuang, S Zhang, W Liu
Applied and Environmental Microbiology 74 (6), 1820-1828, 2008
Engineering of acetyl-CoA metabolism for the improved production of polyhydroxybutyrate in Saccharomyces cerevisiae
K Kocharin, Y Chen, V Siewers, J Nielsen
Amb Express 2 (1), 1-11, 2012
Enhancing the copy number of episomal plasmids in Saccharomyces cerevisiae for improved protein production
Y Chen, S Partow, G Scalcinati, V Siewers, J Nielsen
FEMS yeast research 12 (5), 598-607, 2012
From flavors and pharmaceuticals to advanced biofuels: Production of isoprenoids in Saccharomyces cerevisiae
S Tippmann, Y Chen, V Siewers, J Nielsen
Biotechnology journal 8 (12), 1435-1444, 2013
Electrochemiluminescence imaging for parallel single-cell analysis of active membrane cholesterol
J Zhou, G Ma, Y Chen, D Fang, D Jiang, H Chen
Analytical chemistry 87 (16), 8138-8143, 2015
Engineering and systems-level analysis of Saccharomyces cerevisiae for production of 3-hydroxypropionic acid via malonyl-CoA reductase-dependent pathway
KR Kildegaard, NB Jensen, K Schneider, E Czarnotta, E Özdemir, T Klein, ...
Microbial cell factories 15 (1), 1-13, 2016
Rewiring carbon metabolism in yeast for high level production of aromatic chemicals
Q Liu, T Yu, X Li, Y Chen, K Campbell, J Nielsen, Y Chen
Nature communications 10 (1), 1-13, 2019
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