| Crystal structure of aspirin-acetylated human cyclooxygenase-2: insight into the formation of products with reversed stereochemistry MJ Lucido, BJ Orlando, AJ Vecchio, MG Malkowski Biochemistry 55 (8), 1226-1238, 2016 | 195 | 2016 |
| Structure and mechanism of the mitochondrial Ca2+ uniporter holocomplex M Fan, J Zhang, CW Tsai, BJ Orlando, M Rodriguez, Y Xu, M Liao, ... Nature 582 (7810), 129-133, 2020 | 185 | 2020 |
| Substrate-selective inhibition of cyclooxygeanse-2 by fenamic acid derivatives is dependent on peroxide tone BJ Orlando, MG Malkowski Journal of Biological Chemistry 291 (29), 15069-15081, 2016 | 166 | 2016 |
| The structure of ibuprofen bound to cyclooxygenase-2 BJ Orlando, MJ Lucido, MG Malkowski Journal of structural biology 189 (1), 62-66, 2015 | 156 | 2015 |
| ABCG2 transports anticancer drugs via a closed-to-open switch BJ Orlando, M Liao Nature communications 11 (1), 2264, 2020 | 151 | 2020 |
| Structural basis of lipopolysaccharide extraction by the LptB2FGC complex Y Li, BJ Orlando, M Liao Nature 567 (7749), 486-490, 2019 | 146 | 2019 |
| Crystal structure of rofecoxib bound to human cyclooxygenase-2 BJ Orlando, MG Malkowski Acta Crystallographica Section F: Structural Biology Communications 72 (10 …, 2016 | 139 | 2016 |
| X-ray and cryo-EM structures of the mitochondrial calcium uniporter C Fan, M Fan, BJ Orlando, NM Fastman, J Zhang, Y Xu, MG Chambers, ... Nature 559 (7715), 575-579, 2018 | 127 | 2018 |
| Large protein organelles form a new iron sequestration system with high storage capacity TW Giessen, BJ Orlando, AA Verdegaal, MG Chambers, J Gardener, ... Elife 8, e46070, 2019 | 109 | 2019 |
| Structure and mechanism of the cation–chloride cotransporter NKCC1 TA Chew, BJ Orlando, J Zhang, NR Latorraca, A Wang, SA Hollingsworth, ... Nature 572 (7770), 488-492, 2019 | 101 | 2019 |
| Investigating substrate promiscuity in cyclooxygenase-2: the role of Arg-120 and residues lining the hydrophobic groove AJ Vecchio, BJ Orlando, R Nandagiri, MG Malkowski Journal of Biological Chemistry 287 (29), 24619-24630, 2012 | 52 | 2012 |
| Fatty acid binding to the allosteric subunit of cyclooxygenase-2 relieves a tonic inhibition of the catalytic subunit L Dong, C Yuan, BJ Orlando, MG Malkowski, WL Smith Journal of Biological Chemistry 291 (49), 25641-25655, 2016 | 28 | 2016 |
| Cyclooxygenase-2 catalysis and inhibition in lipid bilayer nanodiscs BJ Orlando, DR McDougle, MJ Lucido, ET Eng, LA Graham, C Schneider, ... Archives of biochemistry and biophysics 546, 33-40, 2014 | 24 | 2014 |
| Architecture of a complete Bce-type antimicrobial peptide resistance module NL George, BJ Orlando Nature Communications 14 (1), 3896, 2023 | 13 | 2023 |
| Pulsed dipolar spectroscopy reveals that tyrosyl radicals are generated in both monomers of the cyclooxygenase-2 dimer BJ Orlando, PP Borbat, ER Georgieva, JH Freed, MG Malkowski Biochemistry 54 (50), 7309-7312, 2015 | 12 | 2015 |
| Conformational snapshots of the bacitracin sensing and resistance transporter BceAB NL George, AL Schilmiller, BJ Orlando Proceedings of the National Academy of Sciences 119 (14), e2123268119, 2022 | 11 | 2022 |
| High-resolution views of lipopolysaccharide translocation driven by ABC transporters MsbA and LptB2FGC F Thélot, BJ Orlando, Y Li, M Liao Current opinion in structural biology 63, 26-33, 2020 | 10 | 2020 |
| Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes BJ Orlando, PK Dominik, S Roy, CP Ogbu, SK Erramilli, AA Kossiakoff, ... Journal of Biological Chemistry 298 (9), 2022 | 4 | 2022 |
| Perception and protection: The role of Bce-modules in antimicrobial peptide resistance BJ Orlando Biochimica et Biophysica Acta (BBA)-Biomembranes, 184309, 2024 | | 2024 |
| Cryo-EM structures of human claudin-4 in complex with its bacterial toxin antagonist enabled by synthetic antibody fragments reveal targeting mechanisms and therapeutic potential BJ Orlando, PK Dominik, S Roy, C Ogbu, SK Erramilli, AA Kossiakoff, ... Biophysical Journal 121 (3), 167a-168a, 2022 | | 2022 |
