Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas Cancer Genome Atlas Research Network New England Journal of Medicine 372 (26), 2481-2498, 2015 | 2523 | 2015 |
Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma M Ceccarelli, FP Barthel, TM Malta, TS Sabedot, SR Salama, BA Murray, ... Cell 164 (3), 550-563, 2016 | 1710 | 2016 |
Predicting cancer outcomes from histology and genomics using convolutional networks P Mobadersany, S Yousefi, M Amgad, DA Gutman, JS Barnholtz-Sloan, ... Proceedings of the National Academy of Sciences 115 (13), E2970-E2979, 2018 | 675 | 2018 |
Comprehensive and integrated genomic characterization of adult soft tissue sarcomas AJ Lazar, MD McLellan, MH Bailey, CA Miller, EL Appelbaum, MG Cordes, ... Cell 171 (4), 950-965, 2017 | 643 | 2017 |
MR imaging predictors of molecular profile and survival: multi-institutional study of the TCGA glioblastoma data set DA Gutman, LAD Cooper, SN Hwang, CA Holder, JJ Gao, TD Aurora, ... Radiology 267 (2), 560-569, 2013 | 412 | 2013 |
T2–FLAIR Mismatch, an Imaging Biomarker for IDH and 1p/19q Status in Lower-grade Gliomas: A TCGA/TCIA ProjectT2–FLAIR Mismatch Predicts Low-Grade Glioma Molecular Class SH Patel, LM Poisson, DJ Brat, Y Zhou, L Cooper, M Snuderl, C Thomas, ... Clinical Cancer Research 23 (20), 6078-6085, 2017 | 244 | 2017 |
The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma LAD Cooper, DA Gutman, C Chisolm, C Appin, J Kong, Y Rong, T Kurc, ... The American journal of pathology 180 (5), 2108-2119, 2012 | 223 | 2012 |
Deep learning enables robust assessment and selection of human blastocysts after in vitro fertilization P Khosravi, E Kazemi, Q Zhan, JE Malmsten, M Toschi, P Zisimopoulos, ... NPJ digital medicine 2 (1), 21, 2019 | 218 | 2019 |
Predicting clinical outcomes from large scale cancer genomic profiles with deep survival models S Yousefi, F Amrollahi, M Amgad, C Dong, JE Lewis, C Song, DA Gutman, ... Scientific reports 7 (1), 11707, 2017 | 182 | 2017 |
Tumor-Infiltrating Lymphocytes in Glioblastoma Are Associated with Specific Genomic Alterations and Related to Transcriptional ClassTumor-Infiltrating Lymphocytes in Glioblastoma WC Rutledge, J Kong, J Gao, DA Gutman, LAD Cooper, C Appin, Y Park, ... Clinical Cancer Research 19 (18), 4951-4960, 2013 | 180 | 2013 |
The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies Z Li, AA Ivanov, R Su, V Gonzalez-Pecchi, Q Qi, S Liu, P Webber, ... Nature communications 8 (1), 14356, 2017 | 170 | 2017 |
The proneural molecular signature is enriched in oligodendrogliomas and predicts improved survival among diffuse gliomas LAD Cooper, DA Gutman, Q Long, BA Johnson, SR Cholleti, T Kurc, ... PloS one 5 (9), e12548, 2010 | 158 | 2010 |
Cancer Digital Slide Archive: an informatics resource to support integrated in silico analysis of TCGA pathology data DA Gutman, J Cobb, D Somanna, Y Park, F Wang, T Kurc, JH Saltz, ... Journal of the American Medical Informatics Association 20 (6), 1091-1098, 2013 | 152 | 2013 |
PanCancer insights from The Cancer Genome Atlas: the pathologist's perspective LA Cooper, EG Demicco, JH Saltz, RT Powell, A Rao, AJ Lazar The Journal of pathology 244 (5), 512-524, 2018 | 141 | 2018 |
Structured crowdsourcing enables convolutional segmentation of histology images M Amgad, H Elfandy, H Hussein, LA Atteya, MAT Elsebaie, LS Abo Elnasr, ... Bioinformatics 35 (18), 3461-3467, 2019 | 116 | 2019 |
Machine-based morphologic analysis of glioblastoma using whole-slide pathology images uncovers clinically relevant molecular correlates J Kong, LAD Cooper, F Wang, J Gao, G Teodoro, L Scarpace, ... PloS one 8 (11), e81049, 2013 | 114 | 2013 |
Integrated morphologic analysis for the identification and characterization of disease subtypes LAD Cooper, J Kong, DA Gutman, F Wang, J Gao, C Appin, S Cholleti, ... Journal of the American Medical Informatics Association 19 (2), 317-323, 2012 | 112 | 2012 |
An expanded universe of cancer targets WC Hahn, JS Bader, TP Braun, A Califano, PA Clemons, BJ Druker, ... Cell 184 (5), 1142-1155, 2021 | 107 | 2021 |
The digital slide archive: A software platform for management, integration, and analysis of histology for cancer research DA Gutman, M Khalilia, S Lee, M Nalisnik, Z Mullen, J Beezley, ... Cancer research 77 (21), e75-e78, 2017 | 107 | 2017 |
Somatic mutations associated with MRI-derived volumetric features in glioblastoma DA Gutman, WD Dunn, P Grossmann, LAD Cooper, CA Holder, KL Ligon, ... Neuroradiology 57, 1227-1237, 2015 | 100 | 2015 |