Conserved motifs reveal details of ancestry and structure in the small TIM chaperones of the mitochondrial intermembrane space IE Gentle, AJ Perry, FH Alcock, VA Likić, P Dolezal, ET Ng, AW Purcell, ... Molecular biology and evolution 24 (5), 1149-1160, 2007 | 109 | 2007 |
Live cell imaging shows reversible assembly of the TatA component of the twin-arginine protein transport system F Alcock, MAB Baker, NP Greene, T Palmer, MI Wallace, BC Berks Proceedings of the National Academy of Sciences 110 (38), E3650-E3659, 2013 | 83 | 2013 |
Minor modifications and major adaptations: the evolution of molecular machines driving mitochondrial protein import V Hewitt, F Alcock, T Lithgow Biochimica et Biophysica Acta (BBA)-Biomembranes 1808 (3), 947-954, 2011 | 82 | 2011 |
The structural basis of the TIM10 chaperone assembly H Lu, AP Golovanov, F Alcock, JG Grossmann, S Allen, LY Lian, ... Journal of Biological Chemistry 279 (18), 18959-18966, 2004 | 76 | 2004 |
Assembling the Tat protein translocase F Alcock, PJ Stansfeld, H Basit, J Habersetzer, MAB Baker, T Palmer, ... elife 5, e20718, 2016 | 64 | 2016 |
Mammalian OS-9 is upregulated in response to endoplasmic reticulum stress and facilitates ubiquitination of misfolded glycoproteins F Alcock, E Swanton Journal of molecular biology 385 (4), 1032-1042, 2009 | 60 | 2009 |
Structure and mechanism of the proton-driven motor that powers type 9 secretion and gliding motility R Hennell James, JC Deme, A Kjӕr, F Alcock, A Silale, F Lauber, ... Nature microbiology 6 (2), 221-233, 2021 | 53 | 2021 |
Distinct domains of small Tims involved in subunit interaction and substrate recognition MAS Vergnolle, C Baud, AP Golovanov, F Alcock, P Luciano, LY Lian, ... Journal of molecular biology 351 (4), 839-849, 2005 | 53 | 2005 |
Commensal Escherichiacoli are a reservoir for the transfer of XDR plasmids into epidemic fluoroquinolone-resistant Shigella sonnei P Thanh Duy, TN Thi Nguyen, D Vu Thuy, H Chung The, F Alcock, ... Nature microbiology 5 (2), 256-264, 2020 | 50 | 2020 |
Tinkering inside the organelle F Alcock, A Clements, C Webb, T Lithgow Science 327 (5966), 649-650, 2010 | 48 | 2010 |
Conserved substrate binding by chaperones in the bacterial periplasm and the mitochondrial intermembrane space FH Alcock, JG Grossmann, IE Gentle, VA Likić, T Lithgow, K Tokatlidis Biochemical Journal 409 (2), 377-387, 2008 | 42 | 2008 |
The TatC component of the twin‐arginine protein translocase functions as an obligate oligomer F Cléon, J Habersetzer, F Alcock, H Kneuper, PJ Stansfeld, H Basit, ... Molecular microbiology 98 (1), 111-129, 2015 | 33 | 2015 |
A signal sequence suppressor mutant that stabilizes an assembled state of the twin arginine translocase Q Huang, F Alcock, H Kneuper, JC Deme, SE Rollauer, SM Lea, BC Berks, ... Proceedings of the National Academy of Sciences 114 (10), E1958-E1967, 2017 | 31 | 2017 |
A Small Tim Homohexamer in the Relict Mitochondrion of Cryptosporidium F Alcock, CT Webb, P Dolezal, V Hewitt, M Shingu-Vasquez, VA Likić, ... Molecular biology and evolution 29 (1), 113-122, 2012 | 27 | 2012 |
Evolution of mitochondrial TAT translocases illustrates the loss of bacterial protein transport machines in mitochondria M Petrů, J Wideman, K Moore, F Alcock, T Palmer, P Doležal BMC biology 16, 1-14, 2018 | 24 | 2018 |
Mitochondrial ATP‐independent chaperones N Petrakis, F Alcock, K Tokatlidis IUBMB life 61 (9), 909-914, 2009 | 17 | 2009 |
Mutation of conserved charged residues in mitochondrial TIM10 subunits precludes TIM10 complex assembly, but does not abolish growth of yeast cells MAS Vergnolle, FH Alcock, N Petrakis, K Tokatlidis Journal of molecular biology 371 (5), 1315-1324, 2007 | 17 | 2007 |
Complementing structural information of modular proteins with small angle neutron scattering and contrast variation JG Grossmann, AJ Callaghan, MJ Marcaida, BF Luisi, FH Alcock, ... European Biophysics Journal 37, 603-611, 2008 | 12 | 2008 |
In vivo experiments do not support the charge zipper model for Tat translocase assembly F Alcock, MPM Damen, J Levring, BC Berks Elife 6, e30127, 2017 | 10 | 2017 |
Three small partner proteins facilitate the type VII-dependent secretion of an antibacterial nuclease Y Yang, E Boardman, J Deme, F Alcock, S Lea, T Palmer Mbio 14 (5), e02100-23, 2023 | 7* | 2023 |