| Catalytic amination of 2-substituted pyridines with hydrazine derivatives JB Arterburn, KV Rao, R Ramdas, BR Dible Organic letters 3 (9), 1351-1354, 2001 | 112 | 2001 |
| Characterization of the potency, selectivity, and pharmacokinetic profile for six adenosine A2A receptor antagonists M Yang, D Soohoo, S Soelaiman, R Kalla, J Zablocki, N Chu, K Leung, ... Naunyn-Schmiedeberg's archives of pharmacology 375, 133-144, 2007 | 91 | 2007 |
| Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets RM Cox, JD Wolf, CM Lieber, J Sourimant, MJ Lin, D Babusis, V DuPont, ... Nature Communications 12 (1), 6415, 2021 | 81 | 2021 |
| Novel 1,3-Disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) Xanthines: High Affinity and Selective A2B Adenosine Receptor Antagonists RV Kalla, E Elzein, T Perry, X Li, V Palle, V Varkhedkar, A Gimbel, T Maa, ... Journal of medicinal chemistry 49 (12), 3682-3692, 2006 | 81 | 2006 |
| A2B adenosine receptor antagonists R Kalla, T Perry, E Elzein, V Varkhedkar, X Li, P Ibrahim, V Palle, D Xiao, ... US Patent 6,825,349, 2004 | 80 | 2004 |
| Discovery of a Novel A2B Adenosine Receptor Antagonist as a Clinical Candidate for Chronic Inflammatory Airway Diseases E Elzein, RV Kalla, X Li, T Perry, A Gimbel, D Zeng, D Lustig, K Leung, ... Journal of medicinal chemistry 51 (7), 2267-2278, 2008 | 77 | 2008 |
| The discovery of a selective, high affinity A2B adenosine receptor antagonist for the potential treatment of asthma J Zablocki, R Kalla, T Perry, V Palle, V Varkhedkar, D Xiao, A Piscopio, ... Bioorganic & medicinal chemistry letters 15 (3), 609-612, 2005 | 72 | 2005 |
| A2B adenosine receptor antagonists R Kalla, T Perry, E Elzein, V Varkhedkar, X Li, P Ibrahim, V Palle, D Xiao, ... US Patent 6,977,300, 2005 | 70 | 2005 |
| A2B adenosine receptor antagonists R Kalla, T Perry, E Elzein, V Varkhedkar, X Li, P Ibrahim, V Palle, D Xiao, ... US Patent 6,977,300, 2005 | 69 | 2005 |
| Synthesis of 17-α-Substituted Estradiol-Pyridin-2-yl Hydrazine Conjugates as Effective Ligands for Labeling with Alberto's Complex fac-[Re(OH2)3(CO)3]+ in … JB Arterburn, C Corona, KV Rao, KE Carlson, JA Katzenellenbogen The Journal of Organic Chemistry 68 (18), 7063-7070, 2003 | 69 | 2003 |
| Progress in the discovery of selective, high affinity A2B adenosine receptor antagonists as clinical candidates RV Kalla, J Zablocki Purinergic signalling 5, 21-29, 2009 | 59 | 2009 |
| Fused heterocyclic compounds as ion channel modulators B Corkey, E Elzein, R Jiang, R Kalla, T Kobayashi, D Koltun, X Li, G Notte, ... US Patent 8,952,034, 2015 | 56 | 2015 |
| Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice A Schäfer, DR Martinez, JJ Won, RM Meganck, FR Moreira, AJ Brown, ... Science Translational Medicine 14 (643), eabm3410, 2022 | 54 | 2022 |
| Novel 1, 3-dipropyl-8-(1-heteroarylmethyl-1H-pyrazol-4-yl)-xanthine derivatives as high affinity and selective A2B adenosine receptor antagonists E Elzein, R Kalla, X Li, T Perry, E Parkhill, V Palle, V Varkhedkar, ... Bioorganic & medicinal chemistry letters 16 (2), 302-306, 2006 | 54 | 2006 |
| A2B adenosine receptor antagonists E Elzein, R Kalla, T Marquart, J Zablocki, X Li US Patent 7,125,993, 2006 | 48 | 2006 |
| Selective, high affinity A2B adenosine receptor antagonists: N-1 monosubstituted 8-(pyrazol-4-yl) xanthines RV Kalla, E Elzein, T Perry, X Li, A Gimbel, M Yang, D Zeng, J Zablocki Bioorganic & medicinal chemistry letters 18 (4), 1397-1401, 2008 | 47 | 2008 |
| Recent Developments in A2B Adenosine Receptor Ligands RV Kalla, J Zablocki, MA Tabrizi, PG Baraldi Adenosine Receptors in Health and Disease, 99-122, 2009 | 42 | 2009 |
| Functionalized rhenium (V) organoimido complexes as potential radiopharmaceuticals. 2. Synthesis, structural characterization, and reactivity of N-succinimidyl ester … JB Arterburn, KV Rao, DM Goreham, MV Valenzuela, MS Holguin, ... Organometallics 19 (9), 1789-1795, 2000 | 41 | 2000 |
| Fused heterocyclic compounds as ion channel modulators B Corkey, E Elzein, R Jiang, R Kalla, T Kobayashi, D Koltun, X Li, G Notte, ... US Patent 8,952,034, 2015 | 38 | 2015 |
| Prodrugs of A2B adenosine receptor antagonists R Kalla, D Koltun, J Zablocki, E Elzein US Patent 7,625,881, 2009 | 38 | 2009 |
