Lihua Julie Zhu
Lihua Julie Zhu
Professor and Head of Bioinformatics Core, MCCB, University of Massachusetts Medical School
Verified email at umassmed.edu - Homepage
TitleCited byYear
Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases
X Meng, MB Noyes, LJ Zhu, ND Lawson, SA Wolfe
Nature biotechnology 26 (6), 695, 2008
8202008
ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data
LJ Zhu, C Gazin, ND Lawson, H Pagès, SM Lin, DS Lapointe, MR Green
BMC bioinformatics 11 (1), 237, 2010
4342010
Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
H Yin, CQ Song, JR Dorkin, LJ Zhu, Y Li, Q Wu, A Park, J Yang, S Suresh, ...
Nature biotechnology 34 (3), 328, 2016
3982016
Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome
CM Oslowski, T Hara, B O'Sullivan-Murphy, K Kanekura, S Lu, M Hara, ...
Cell metabolism 16 (2), 265-273, 2012
3972012
Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum strain ATCC 25586
V Kapatral, I Anderson, N Ivanova, G Reznik, T Los, A Lykidis, ...
Journal of bacteriology 184 (7), 2005-2018, 2002
3342002
Annotating the human genome with Disease Ontology
JD Osborne, J Flatow, M Holko, SM Lin, WA Kibbe, LJ Zhu, MI Danila, ...
BMC genomics 10 (1), S6, 2009
2572009
The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation
MA Umbarger, E Toro, MA Wright, GJ Porreca, D Bau, SH Hong, MJ Fero, ...
Molecular cell 44 (2), 252-264, 2011
2102011
FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system
LJ Zhu, RG Christensen, M Kazemian, CJ Hull, MS Enuameh, ...
Nucleic acids research 39 (suppl_1), D111-D117, 2010
1702010
Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants
A Bansal, LJ Zhu, K Yen, HA Tissenbaum
Proceedings of the National Academy of Sciences 112 (3), E277-E286, 2015
1482015
Diet-induced developmental acceleration independent of TOR and insulin in C. elegans
LT MacNeil, E Watson, HE Arda, LJ Zhu, AJM Walhout
Cell 153 (1), 240-252, 2013
1332013
A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications
Z Sheng, L Li, LJ Zhu, TW Smith, A Demers, AH Ross, RP Moser, ...
Nature medicine 16 (6), 671, 2010
1322010
miR-221 is required for endothelial tip cell behaviors during vascular development
S Nicoli, CP Knyphausen, LJ Zhu, A Lakshmanan, ND Lawson
Developmental cell 22 (2), 418-429, 2012
1292012
Zinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleases
A Gupta, X Meng, LJ Zhu, ND Lawson, SA Wolfe
Nucleic acids research 39 (1), 381-392, 2010
1162010
Nuclear factor-κB-mediated transforming growth factor-β-induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy
Q Zhang, BT Helfand, TL Jang, LJ Zhu, L Chen, XJ Yang, J Kozlowski, ...
Clinical cancer research 15 (10), 3557-3567, 2009
1002009
CRISPRseek: a bioconductor package to identify target-specific guide RNAs for CRISPR-Cas9 genome-editing systems
LJ Zhu, BR Holmes, N Aronin, MH Brodsky
PloS one 9 (9), e108424, 2014
982014
BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription
Z Sheng, L Ma, JE Sun, LJ Zhu, MR Green
Blood 118 (10), 2840-2848, 2011
932011
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing
H Yin, CQ Song, S Suresh, Q Wu, S Walsh, LH Rhym, E Mintzer, ...
Nature biotechnology 35 (12), 1179, 2017
922017
The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis
M Rajurkar, WE De Jesus-Monge, DR Driscoll, VA Appleman, H Huang, ...
Proceedings of the National Academy of Sciences 109 (17), E1038-E1047, 2012
922012
Histone acetyltransferase Rtt109 is required for Candida albicans pathogenesis
JL da Rosa, VL Boyartchuk, LJ Zhu, PD Kaufman
Proceedings of the National Academy of Sciences 107 (4), 1594-1599, 2010
882010
DNA-binding-domain fusions enhance the targeting range and precision of Cas9
MF Bolukbasi, A Gupta, S Oikemus, AG Derr, M Garber, MH Brodsky, ...
Nature methods 12 (12), 1150, 2015
832015
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