| DAOSTORM: an algorithm for high-density super-resolution microscopy SJ Holden, S Uphoff, AN Kapanidis Nature methods 8 (4), 279-280, 2011 | 508 | 2011 |
| Live-cell superresolution microscopy reveals the organization of RNA polymerase in the bacterial nucleoid M Stracy, C Lesterlin, F Garza de Leon, S Uphoff, P Zawadzki, ... Proceedings of the National Academy of Sciences 112 (32), E4390-E4399, 2015 | 264 | 2015 |
| In vivo architecture and action of bacterial structural maintenance of chromosome proteins A Badrinarayanan, R Reyes-Lamothe, S Uphoff, MC Leake, DJ Sherratt Science 338 (6106), 528-531, 2012 | 259 | 2012 |
| Defining the limits of single-molecule FRET resolution in TIRF microscopy SJ Holden, S Uphoff, J Hohlbein, D Yadin, L Le Reste, OJ Britton, ... Biophysical journal 99 (9), 3102-3111, 2010 | 226 | 2010 |
| Imaging cellular structures in super-resolution with SIM, STED and Localisation Microscopy: A practical comparison E Wegel, A Göhler, BC Lagerholm, A Wainman, S Uphoff, R Kaufmann, ... Scientific reports 6 (1), 27290, 2016 | 222 | 2016 |
| Single-molecule DNA repair in live bacteria S Uphoff, R Reyes-Lamothe, F Garza de Leon, DJ Sherratt, AN Kapanidis Proceedings of the National Academy of Sciences 110 (20), 8063-8068, 2013 | 209 | 2013 |
| Stochastic activation of a DNA damage response causes cell-to-cell mutation rate variation S Uphoff, ND Lord, B Okumus, L Potvin-Trottier, DJ Sherratt, J Paulsson Science 351 (6277), 1094-1097, 2016 | 161 | 2016 |
| Frequent exchange of the DNA polymerase during bacterial chromosome replication TR Beattie, N Kapadia, E Nicolas, S Uphoff, AJM Wollman, MC Leake, ... Elife 6, e21763, 2017 | 132 | 2017 |
| Monitoring multiple distances within a single molecule using switchable FRET S Uphoff, SJ Holden, L Le Reste, J Periz, S Van De Linde, M Heilemann, ... Nature methods 7 (10), 831-836, 2010 | 126 | 2010 |
| Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli M Stracy, M Jaciuk, S Uphoff, AN Kapanidis, M Nowotny, DJ Sherratt, ... Nature communications 7 (1), 12568, 2016 | 115 | 2016 |
| Scc2/Nipbl hops between chromosomal cohesin rings after loading J Rhodes, D Mazza, K Nasmyth, S Uphoff Elife 6, e30000, 2017 | 99 | 2017 |
| Long-lived intracellular single-molecule fluorescence using electroporated molecules R Crawford, JP Torella, L Aigrain, A Plochowietz, K Gryte, S Uphoff, ... Biophysical journal 105 (11), 2439-2450, 2013 | 99 | 2013 |
| In vivo single-molecule imaging of bacterial DNA replication, transcription, and repair M Stracy, S Uphoff, FG de Leon, AN Kapanidis FEBS letters 588 (19), 3585-3594, 2014 | 85 | 2014 |
| The SMC complex MukBEF recruits topoisomerase IV to the origin of replication region in live Escherichia coli E Nicolas, AL Upton, S Uphoff, O Henry, A Badrinarayanan, D Sherratt MBio 5 (1), 10.1128/mbio. 01001-13, 2014 | 72 | 2014 |
| Choosing the right label for single-molecule tracking in live bacteria: side-by-side comparison of photoactivatable fluorescent protein and Halo tag dyes N Banaz, J Mäkelä, S Uphoff Journal of physics D: Applied physics 52 (6), 064002, 2018 | 65 | 2018 |
| Transient non-specific DNA binding dominates the target search of bacterial DNA-binding proteins M Stracy, J Schweizer, DJ Sherratt, AN Kapanidis, S Uphoff, C Lesterlin Molecular cell 81 (7), 1499-1514. e6, 2021 | 63 | 2021 |
| Real-time dynamics of mutagenesis reveal the chronology of DNA repair and damage tolerance responses in single cells S Uphoff Proceedings of the National Academy of Sciences 115 (28), E6516-E6525, 2018 | 63 | 2018 |
| Understanding protein mobility in bacteria by tracking single molecules AN Kapanidis, S Uphoff, M Stracy Journal of molecular biology 430 (22), 4443-4455, 2018 | 61 | 2018 |
| Single-molecule imaging of LexA degradation in Escherichia coli elucidates regulatory mechanisms and heterogeneity of the SOS response EC Jones, S Uphoff Nature microbiology 6 (8), 981-990, 2021 | 47 | 2021 |
| DNA ADP-ribosylation stalls replication and is reversed by RecF-mediated homologous recombination and nucleotide excision repair E Lawarée, G Jankevicius, C Cooper, I Ahel, S Uphoff, CM Tang Cell reports 30 (5), 1373-1384. e4, 2020 | 41 | 2020 |
Achillefs KapanidisProfessor in Biological Physics, University of OxfordVerified email at physics.ox.ac.uk
