Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence L Gordon, JE Joo, JE Powell, M Ollikainen, B Novakovic, X Li, ... Genome research 22 (8), 1395-1406, 2012 | 308 | 2012 |
Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of … D Martino, YJ Loke, L Gordon, M Ollikainen, MN Cruickshank, R Saffery, ... Genome biology 14, 1-14, 2013 | 214 | 2013 |
Analysis of epigenetic changes in survivors of preterm birth reveals the effect of gestational age and evidence for a long term legacy MN Cruickshank, A Oshlack, C Theda, PG Davis, D Martino, P Sheehan, ... Genome medicine 5, 1-12, 2013 | 121 | 2013 |
A critical assessment of the factors affecting reporter gene assays for promoter SNP function: a reassessment of− 308 TNF polymorphism function using a novel integrated … M Karimi, LC Goldie, MN Cruickshank, EK Moses, LJ Abraham European journal of human genetics 17 (11), 1454-1462, 2009 | 90 | 2009 |
Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers E Wang, A Sorolla, PT Cunningham, HM Bogdawa, S Beck, E Golden, ... Oncogene 38 (1), 140-150, 2019 | 68 | 2019 |
The impact of histone post-translational modifications on developmental gene regulation MN Cruickshank, P Besant, D Ulgiati Amino acids 39, 1087-1105, 2010 | 34 | 2010 |
Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin MN Cruickshank, J Ford, LC Cheung, J Heng, S Singh, J Wells, TW Failes, ... Leukemia 31 (1), 40-50, 2017 | 33 | 2017 |
The role of notch signaling in the development of a normal B‐cell repertoire MN Cruickshank, D Ulgiati Immunology and cell biology 88 (2), 117-124, 2010 | 33 | 2010 |
Human active X-specific DNA methylation events showing stability across time and tissues JE Joo, B Novakovic, M Cruickshank, LW Doyle, JM Craig, R Saffery European Journal of Human Genetics 22 (12), 1376-1381, 2014 | 27 | 2014 |
Quantitative differences in chromatin accessibility across regulatory regions can be directly compared in distinct cell-types M Cruickshank, E Fenwick, LJ Abraham, D Ulgiati Biochemical and biophysical research communications 367 (2), 349-355, 2008 | 27 | 2008 |
Promoter polymorphisms in two overlapping 6p25 genes implicate mitochondrial proteins in cognitive deficit in schizophrenia A Jablensky, D Angelicheva, GJ Donohoe, M Cruickshank, DN Azmanov, ... Molecular psychiatry 17 (12), 1328-1339, 2012 | 24 | 2012 |
Going back to the future with Guthrie-powered epigenome-wide association studies MN Cruickshank, J Pitt, JM Craig Genome medicine 4, 1-4, 2012 | 21 | 2012 |
Acquired resistance during adoptive cell therapy by transcriptional silencing of immunogenic antigens B Wylie, J Chee, CA Forbes, M Booth, SR Stone, A Buzzai, A Abad, ... Oncoimmunology, 2019 | 20 | 2019 |
Transcriptional effects of a lupus-associated polymorphism in the 5′ untranslated region (UTR) of human complement receptor 2 (CR2/CD21) MN Cruickshank, M Karimi, RL Mason, E Fenwick, T Mercer, BP Tsao, ... Molecular immunology 52 (3-4), 165-173, 2012 | 17 | 2012 |
Preclinical efficacy of azacitidine and venetoclax for infant KMT2A-rearranged acute lymphoblastic leukemia reveals a new therapeutic strategy LC Cheung, C Aya-Bonilla, MN Cruickshank, SK Chiu, V Kuek, ... Leukemia 37 (1), 61-71, 2023 | 15 | 2023 |
Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia T Isobe, M Takagi, A Sato-Otsubo, A Nishimura, G Nagae, C Yamagishi, ... Nature communications 13 (1), 4501, 2022 | 15 | 2022 |
Cell-and stage-specific chromatin structure across the complement receptor 2 (CR2/CD21) promoter coincide with CBF1 and C/EBP-β binding in B cells MN Cruickshank, E Fenwick, M Karimi, LJ Abraham, D Ulgiati Molecular immunology 46 (13), 2613-2622, 2009 | 15 | 2009 |
CD8+XCR1neg Dendritic Cells Express High Levels of Toll-Like Receptor 5 and a Unique Complement of Endocytic Receptors B Wylie, J Read, AC Buzzai, T Wagner, N Troy, G Syn, SR Stone, B Foley, ... Frontiers in Immunology 9, 2990, 2019 | 13 | 2019 |
IFNβ is a potent adjuvant for cancer vaccination strategies KM Audsley, T Wagner, C Ta, HV Newnes, AC Buzzai, SA Barnes, ... Frontiers in Immunology 12, 735133, 2021 | 12 | 2021 |
Impaired T cell proliferation by ex vivo BET-inhibition impedes adoptive immunotherapy in a murine melanoma model J Chee, C Wilson, A Buzzai, B Wylie, CA Forbes, M Booth, N Principe, ... Epigenetics 15 (1-2), 134-144, 2020 | 11 | 2020 |