SARS‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells S Lukassen, RL Chua, T Trefzer, NC Kahn, MA Schneider, T Muley, ... The EMBO journal 39 (10), e105114, 2020 | 1211 | 2020 |
COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis RL Chua, S Lukassen, S Trump, BP Hennig, D Wendisch, F Pott, ... Nature biotechnology 38 (8), 970-979, 2020 | 1063 | 2020 |
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics C Muus, MD Luecken, G Eraslan, L Sikkema, A Waghray, G Heimberg, ... Nature medicine 27 (3), 546-559, 2021 | 315 | 2021 |
Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children J Loske, J Röhmel, S Lukassen, S Stricker, VG Magalhães, J Liebig, ... Nature biotechnology 40 (3), 319-324, 2022 | 313 | 2022 |
Impaired humoral and cellular immunity after SARS-CoV-2 BNT162b2 (tozinameran) prime-boost vaccination in kidney transplant recipients A Sattler, E Schrezenmeier, UA Weber, A Potekhin, F Bachmann, ... The Journal of clinical investigation 131 (14), 2021 | 255 | 2021 |
Hobit- and Blimp-1-driven CD4+ tissue-resident memory T cells control chronic intestinal inflammation S Zundler, E Becker, M Spocinska, M Slawik, L Parga-Vidal, R Stark, ... Nature immunology 20 (3), 288-300, 2019 | 204 | 2019 |
Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19 S Trump, S Lukassen, MS Anker, RL Chua, J Liebig, L Thürmann, ... Nature biotechnology 39 (6), 705-716, 2021 | 172 | 2021 |
Single-nucleus and in situ RNA–sequencing reveal cell topographies in the human pancreas L Tosti, Y Hang, O Debnath, S Tiesmeyer, T Trefzer, K Steiger, FW Ten, ... Gastroenterology 160 (4), 1330-1344. e11, 2021 | 139 | 2021 |
Genome‐wide cooperation of EMT transcription factor ZEB 1 with YAP and AP‐1 in breast cancer N Feldker, F Ferrazzi, H Schuhwerk, SA Widholz, K Guenther, I Frisch, ... The EMBO journal 39 (17), e103209, 2020 | 130 | 2020 |
Inflammation-induced glycolytic switch controls suppressivity of mesenchymal stem cells via STAT1 glycosylation R Jitschin, M Böttcher, D Saul, S Lukassen, H Bruns, R Loschinski, ... Leukemia 33 (7), 1783-1796, 2019 | 74 | 2019 |
Characterization of germ cell differentiation in the male mouse through single-cell RNA sequencing S Lukassen, E Bosch, AB Ekici, A Winterpacht Scientific reports 8 (1), 6521, 2018 | 72 | 2018 |
Single-cell RNA sequencing of adult mouse testes S Lukassen, E Bosch, AB Ekici, A Winterpacht Scientific data 5 (1), 1-7, 2018 | 58 | 2018 |
Arginase impedes the resolution of colitis by altering the microbiome and metabolome J Baier, M Gänsbauer, C Giessler, H Arnold, M Muske, U Schleicher, ... The Journal of clinical investigation 130 (11), 2020 | 56 | 2020 |
Robust methylation‐based classification of brain tumours using nanopore sequencing LP Kuschel, J Hench, S Frank, IB Hench, E Girard, M Blanluet, ... Neuropathology and Applied Neurobiology 49 (1), e12856, 2023 | 44 | 2023 |
In vivo protein complementation demonstrates presynaptic α-synuclein oligomerization and age-dependent accumulation of 8–16-mer oligomer species M Kiechle, B von Einem, L Höfs, P Voehringer, V Grozdanov, D Markx, ... Cell reports 29 (9), 2862-2874. e9, 2019 | 32 | 2019 |
Chromatin-remodeling factor SPOC1 acts as a cellular restriction factor against human cytomegalovirus by repressing the major immediate early promoter A Reichel, AC Stilp, M Scherer, N Reuter, S Lukassen, B Kasmapour, ... Journal of Virology 92 (14), 10.1128/jvi. 00342-18, 2018 | 22 | 2018 |
ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19 M Pietzner, RL Chua, E Wheeler, K Jechow, JDS Willett, H Radbruch, ... Nature Communications 13 (1), 4484, 2022 | 17 | 2022 |
A method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization B Schultz, A Zaliani, C Ebeling, J Reinshagen, D Bojkova, ... Scientific reports 11 (1), 11049, 2021 | 17* | 2021 |
Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early-and late-phase COVID-19 J Radke, J Meinhardt, T Aschman, RL Chua, V Farztdinov, S Lukassen, ... Nature Neuroscience 27 (3), 409-420, 2024 | 12 | 2024 |
A targetable ‘rogue’neutrophil-subset,[CD11b+ DEspR+] immunotype, is associated with severity and mortality in acute respiratory distress syndrome (ARDS) and COVID-19-ARDS VLM Herrera, AJ Walkey, MQ Nguyen, CM Gromisch, JZ Mosaddhegi, ... Scientific Reports 12 (1), 5583, 2022 | 12* | 2022 |