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Trastuzumab deruxtecan in previously treated HER2-positive breast cancer
S Modi, C Saura, T Yamashita, YH Park, SB Kim, K Tamura, F Andre, ...
New England Journal of Medicine 382 (7), 610-621, 2020
15262020
Trastuzumab deruxtecan in previously treated HER2-low advanced breast cancer
S Modi, W Jacot, T Yamashita, J Sohn, M Vidal, E Tokunaga, J Tsurutani, ...
New England Journal of Medicine 387 (1), 9-20, 2022
11282022
The genomic landscape of endocrine-resistant advanced breast cancers
P Razavi, MT Chang, G Xu, C Bandlamudi, DS Ross, N Vasan, Y Cai, ...
Cancer cell 34 (3), 427-438. e6, 2018
7972018
Phase I study of trastuzumab-DM1, an HER2 antibody-drug conjugate, given every 3 weeks to patients with HER2-positive metastatic breast cancer
IE Krop, M Beeram, S Modi, SF Jones, SN Holden, W Yu, S Girish, ...
J Clin Oncol 28 (16), 2698-2704, 2010
6762010
Unlocking the potential of antibody–drug conjugates for cancer therapy
JZ Drago, S Modi, S Chandarlapaty
Nature Reviews Clinical Oncology 18 (6), 327-344, 2021
6042021
Antitumor activity and safety of trastuzumab deruxtecan in patients with HER2-low–expressing advanced breast cancer: results from a phase Ib study
S Modi, H Park, RK Murthy, H Iwata, K Tamura, J Tsurutani, ...
Journal of Clinical Oncology 38 (17), 1887, 2020
5862020
Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers
K Jhaveri, T Taldone, S Modi, G Chiosis
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (3), 742-755, 2012
5092012
HSP90 inhibition is effective in breast cancer: a phase II trial of tanespimycin (17-AAG) plus trastuzumab in patients with HER2-positive metastatic breast cancer progressing …
S Modi, A Stopeck, H Linden, D Solit, S Chandarlapaty, N Rosen, ...
Clinical Cancer Research 17 (15), 5132-5139, 2011
4922011
Systemic therapy for patients with advanced human epidermal growth factor receptor 2–positive breast cancer: American Society of Clinical Oncology clinical practice guideline
SH Giordano, S Temin, JJ Kirshner, S Chandarlapaty, JR Crews, ...
Journal of clinical oncology 32 (19), 2078, 2014
4562014
Combination of trastuzumab and tanespimycin (17-AAG, KOS-953) is safe and active in trastuzumab-refractory HER-2–overexpressing breast cancer: a phase I dose-escalation study
S Modi, AT Stopeck, MS Gordon, D Mendelson, DB Solit, R Bagatell, ...
Journal of clinical oncology 25 (34), 5410-5417, 2007
4122007
A phase II study of trastuzumab emtansine in patients with human epidermal growth factor receptor 2–positive metastatic breast cancer who were previously treated with …
IE Krop, P LoRusso, KD Miller, S Modi, D Yardley, G Rodriguez, ...
Journal of clinical oncology 30 (26), 3234-3241, 2012
4022012
Trastuzumab deruxtecan (DS-8201a) in patients with advanced HER2-positive breast cancer previously treated with trastuzumab emtansine: a dose-expansion, phase 1 study
K Tamura, J Tsurutani, S Takahashi, H Iwata, IE Krop, C Redfern, ...
The Lancet Oncology 20 (6), 816-826, 2019
3302019
A phase I trial of regional mesothelin-targeted CAR T-cell therapy in patients with malignant pleural disease, in combination with the anti–PD-1 agent pembrolizumab
PS Adusumilli, MG Zauderer, I Rivière, SB Solomon, VW Rusch, ...
Cancer discovery 11 (11), 2748-2763, 2021
2652021
Incidence of chemotherapy‐induced, long‐term amenorrhea in patients with breast carcinoma age 40 years and younger after adjuvant anthracycline and taxane
MN Fornier, S Modi, KS Panageas, L Norton, C Hudis
Cancer 104 (8), 1575-1579, 2005
2552005
The epichaperome is an integrated chaperome network that facilitates tumour survival
A Rodina, T Wang, P Yan, EDG Gomes, MPS Dunphy, N Pillarsetty, ...
Nature 538 (7625), 397-401, 2016
2472016
Frequent mutational activation of the PI3K-AKT pathway in trastuzumab-resistant breast cancer
S Chandarlapaty, RA Sakr, D Giri, S Patil, A Heguy, M Morrow, S Modi, ...
Clinical Cancer Research 18 (24), 6784-6791, 2012
2192012
Systemic therapy for patients with advanced human epidermal growth factor receptor 2-positive breast cancer: ASCO clinical practice guideline update
SH Giordano, S Temin, S Chandarlapaty, JR Crews, FJ Esteva, ...
J Clin Oncol 36 (26), 2736-2740, 2018
2182018
Recommendations on disease management for patients with advanced human epidermal growth factor receptor 2–positive breast cancer and brain metastases: American Society of …
N Ramakrishna, S Temin, S Chandarlapaty, JR Crews, NE Davidson, ...
Journal of clinical oncology 32 (19), 2100, 2014
2112014
Trastuzumab deruxtecan (DS-8201a) in patients with advanced HER2-positive gastric cancer: a dose-expansion, phase 1 study
K Shitara, H Iwata, S Takahashi, K Tamura, H Park, S Modi, J Tsurutani, ...
The Lancet Oncology 20 (6), 827-836, 2019
1922019
Heat shock protein 90 inhibitors in the treatment of cancer: current status and future directions
K Jhaveri, SO Ochiana, MPS Dunphy, JF Gerecitano, AD Corben, RI Peter, ...
Expert opinion on investigational drugs 23 (5), 611-628, 2014
1852014
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