Suivre
Hong Ling
Hong Ling
Professor of Biochemistry, University of Western Ontario, London, Canada
Adresse e-mail validée de uwo.ca - Page d'accueil
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Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands
PI Kitov, JM Sadowska, G Mulvey, GD Armstrong, H Ling, NS Pannu, ...
Nature 403 (6770), 669-672, 2000
11202000
Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication
H Ling, F Boudsocq, R Woodgate, W Yang
Cell 107 (1), 91-102, 2001
7472001
Structure of the Shiga-like Toxin I B-Pentamer Complexed with an Analogue of Its Receptor Gb3,
H Ling, A Boodhoo, B Hazes, MD Cummings, GD Armstrong, JL Brunton, ...
Biochemistry 37 (7), 1777-1788, 1998
5631998
Structure of a two‐domain fragment of HIV‐1 integrase: implications for domain organization in the intact protein
JY Wang, H Ling, W Yang, R Craigie
The EMBO journal, 2001
4432001
Replication of a cissyn thymine dimer at atomic resolution
H Ling, F Boudsocq, BS Plosky, R Woodgate, W Yang
Nature 424 (6952), 1083-1087, 2003
2562003
Snapshots of replication through an abasic lesion: structural basis for base substitutions and frameshifts
H Ling, F Boudsocq, R Woodgate, W Yang
Molecular cell 13 (5), 751-762, 2004
2332004
Crystal structure of a benzo [a] pyrene diol epoxide adduct in a ternary complex with a DNA polymerase
H Ling, JM Sayer, BS Plosky, H Yagi, F Boudsocq, R Woodgate, ...
Proceedings of the National Academy of Sciences 101 (8), 2265-2269, 2004
2182004
Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis
A Vaisman, H Ling, R Woodgate, W Yang
The EMBO journal 24 (17), 2957-2967, 2005
2152005
Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication
F Boudsocq, RJ Kokoska, BS Plosky, A Vaisman, H Ling, TA Kunkel, ...
Journal of Biological Chemistry 279 (31), 32932-32940, 2004
1802004
Snapshots of a Y-family DNA polymerase in replication: substrate-induced conformational transitions and implications for fidelity of Dpo4
JH Wong, KA Fiala, Z Suo, H Ling
Journal of molecular biology 379 (2), 317-330, 2008
1022008
A structural gap in Dpo4 supports mutagenic bypass of a major benzo [a] pyrene dG adduct in DNA through template misalignment
J Bauer, G Xing, H Yagi, JM Sayer, DM Jerina, H Ling
Proceedings of the National Academy of Sciences 104 (38), 14905-14910, 2007
942007
Structure-based interpretation of missense mutations in Y-family DNA polymerases and their implications for polymerase function and lesion bypass
F Boudsocq, H Ling, W Yang, R Woodgate
DNA repair 1 (5), 343-358, 2002
862002
Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA
G Xing, K Kirouac, YJ Shin, SD Bell, H Ling
Molecular microbiology 71 (3), 678-691, 2009
842009
Structural basis of error‐prone replication and stalling at a thymine base by human DNA polymerase ι
KN Kirouac, H Ling
The EMBO journal 28 (11), 1644-1654, 2009
802009
Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota
KN Kirouac, H Ling
Proceedings of the National Academy of Sciences 108 (8), 3210-3215, 2011
782011
Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase
KA Fiala, JA Brown, H Ling, AK Kshetry, J Zhang, JS Taylor, W Yang, ...
Journal of molecular biology 365 (3), 590-602, 2007
762007
Mutations in the P3 Protein of Soybean mosaic virus G2 Isolates Determine Virulence on Rsv4-Genotype Soybean
RV Chowda-Reddy, H Sun, H Chen, V Poysa, H Ling, M Gijzen, A Wang
Molecular plant-microbe interactions 24 (1), 37-43, 2011
662011
A mutant Shiga-like toxin IIe bound to its receptor Gb3: structure of a group II Shiga-like toxin with altered binding specificity
H Ling, NS Pannu, A Boodhoo, GD Armstrong, CG Clark, JL Brunton, ...
Structure 8 (3), 253-264, 2000
642000
Structure and mechanism of error-free replication past the major benzo [a] pyrene adduct by human DNA polymerase κ
V Jha, C Bian, G Xing, H Ling
Nucleic acids research 44 (10), 4957-4967, 2016
542016
Structural insight into dynamic bypass of the major cisplatin‐DNA adduct by Y‐family polymerase Dpo4
JHY Wong, JA Brown, Z Suo, P Blum, T Nohmi, H Ling
The EMBO Journal 29 (12), 2059-2069, 2010
452010
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