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Hans Renata
Hans Renata
Bestätigte E-Mail-Adresse bei rice.edu
Titel
Zitiert von
Zitiert von
Jahr
Expanding the enzyme universe: accessing non‐natural reactions by mechanism‐guided directed evolution
H Renata, ZJ Wang, FH Arnold
Angewandte Chemie International Edition 54 (11), 3351-3367, 2015
5272015
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
RK Zhang, K Chen, X Huang, L Wohlschlager, H Renata, FH Arnold
Nature 565 (7737), 67-72, 2019
2642019
Improved cyclopropanation activity of histidine‐ligated cytochrome P450 enables the enantioselective formal synthesis of levomilnacipran
ZJ Wang, H Renata, NE Peck, CC Farwell, PS Coelho, FH Arnold
Angewandte Chemie 126 (26), 6928-6931, 2014
2162014
Cytochrome P450-catalyzed insertion of carbenoids into N–H bonds
Z JaneáWang
Chemical science 5 (2), 598-601, 2014
1862014
Strategic redox relay enables a scalable synthesis of ouabagenin, a bioactive cardenolide
H Renata, Q Zhou, PS Baran
Science 339 (6115), 59-63, 2013
1702013
Development of a concise synthesis of ouabagenin and hydroxylated corticosteroid analogues
H Renata, Q Zhou, G Dunstl, J Felding, RR Merchant, CH Yeh, PS Baran
Journal of the American Chemical Society 137 (3), 1330-1340, 2015
1252015
Remote C–H hydroxylation by an α-ketoglutarate-dependent dioxygenase enables efficient chemoenzymatic synthesis of manzacidin C and proline analogs
CR Zwick III, H Renata
Journal of the American Chemical Society 140 (3), 1165-1169, 2018
1032018
Divergent synthesis of complex diterpenes through a hybrid oxidative approach
X Zhang, E King-Smith, LB Dong, LC Yang, JD Rudolf, B Shen, H Renata
Science 369 (6505), 799-806, 2020
942020
Highly stereoselective biocatalytic synthesis of key cyclopropane intermediate to ticagrelor
KE Hernandez, H Renata, RD Lewis, SBJ Kan, C Zhang, J Forte, ...
ACS catalysis 6 (11), 7810-7813, 2016
852016
Total synthesis of tambromycin by combining chemocatalytic and biocatalytic C− H functionalization
X Zhang, E King‐Smith, H Renata
Angewandte Chemie International Edition 57 (18), 5037-5041, 2018
782018
Merging chemoenzymatic and radical-based retrosynthetic logic for rapid and modular synthesis of oxidized meroterpenoids
J Li, F Li, E King-Smith, H Renata
Nature chemistry 12 (2), 173-179, 2020
732020
Identification of mechanism-based inactivation in P450-catalyzed cyclopropanation facilitates engineering of improved enzymes
H Renata, RD Lewis, MJ Sweredoski, A Moradian, S Hess, ZJ Wang, ...
Journal of the American Chemical Society 138 (38), 12527-12533, 2016
712016
Directed evolution of a bright near-infrared fluorescent rhodopsin using a synthetic chromophore
L Herwig, AJ Rice, CN Bedbrook, RK Zhang, A Lignell, JKB Cahn, ...
Cell chemical biology 24 (3), 415-425, 2017
662017
P450-catalyzed asymmetric cyclopropanation of electron-deficient olefins under aerobic conditions
Z JaneáWang
Catalysis science & technology 4 (10), 3640-3643, 2014
642014
Asymmetric chemoenzymatic synthesis of (−)‐podophyllotoxin and related aryltetralin lignans
J Li, X Zhang, H Renata
Angewandte Chemie International Edition 58 (34), 11657-11660, 2019
622019
Ausdehnung des Enzym‐Universums: Zugang zu nicht‐natürlichen Reaktionen durch mechanismusgeleitete, gerichtete Evolution
H Renata, ZJ Wang, FH Arnold
Angewandte Chemie 127 (11), 3408-3426, 2015
622015
Recent advances in the chemoenzymatic synthesis of bioactive natural products
J Li, A Amatuni, H Renata
Current opinion in chemical biology 55, 111-118, 2020
532020
Harnessing the biocatalytic potential of iron-and α-ketoglutarate-dependent dioxygenases in natural product total synthesis
CR Zwick, H Renata
Natural Product Reports 37 (8), 1065-1079, 2020
522020
Applications of oxygenases in the chemoenzymatic total synthesis of complex natural products
E King-Smith, CR Zwick III, H Renata
Biochemistry 57 (4), 403-412, 2018
492018
Enzymatic CH functionalizations for natural product synthesis
F Li, X Zhang, H Renata
Current opinion in chemical biology 49, 25-32, 2019
482019
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